Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Miller O. Scott"'
Autor:
Miller O. Scott, Dean E. McNulty, Michael L. Doyle, John R. White, Stephen D. Burrows, Peter R. Young, Preston Hensley, Jay R. Knutson, Samuel G. Franklin, Ian Brooks, Denise Porter, Kenneth P. Murphy
Publikováno v:
Biochemistry. 33:12741-12745
Interleukin-8 has been shown by X-ray crystallography and NMR to be a homodimer, suggesting that this is the form which binds to its receptor. Here we measure, for the first time, the monomer-dimer equilibrium of interleukin-8 using analytical ultrac
Autor:
Miller O. Scott, Christopher M. Wiethoff, Anthony P. Green, C. Russell Middaugh, Jason Rexroad, Timothy D. Kierstead
Publikováno v:
Journal of pharmaceutical sciences. 92(3)
Thermally induced structural changes in adenovirus type 5 (Ad) in the presence of either 2 or 10% sucrose were investigated using a variety of biophysical techniques. In solutions containing 2% sucrose, a highly cooperative transition in the structur
Autor:
Timothy D. Kierstead, Irene Beaupré, Miller O. Scott, James Huang, Anthony P. Green, James M. Wilson, Guangping Gao
Publikováno v:
Human gene therapy. 13(16)
Recombinant adenovirus vectors continue to be the preferred vectors for many types of gene therapy. However, issues regarding production and safety as well as the development of a scalable process for these vectors remain a challenge. Additionally, a
Autor:
James J. Foley, Pieter H.E. Groot, Theresa J. Brawner, Jayneeta Makwana, Jane Matthews, Miller O. Scott, John R. White, Appelbaum Edward Robert, Christine Imburgia, Daniel J. O'Shannessy, Dulcie B. Schmidt, Henry M. Sarau, Colin H. Macphee, Theo A. Berkhout, Kevin O'Donnell, Kitty Moores, Nabil Elshourbagy, Mary Reape, Dean E. McNulty
Publikováno v:
The Journal of biological chemistry. 272(26)
Here we describe the characterization of a novel human CC chemokine, tentatively named monocyte chemotactic protein (MCP-4). This chemokine was detected by random sequencing of expressed sequence tags in cDNA libraries. The full-length cDNA revealed