A 6-month inhalation toxicology study in Apoe ^-/- mice demonstrates substantially lower effects of e-vapor aerosol compared with cigarette smoke in the respiratory tract.

Autor: Wong ET; PMI R&D, Philip Morris International Research Laboratories Pte. Ltd, Science Park II, Singapore, 117406, Singapore., Szostak J; PMI R&D, Philip Morris Products S.A, Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland. Justyna.Szostak@pmi.com., Titz B; PMI R&D, Philip Morris Products S.A, Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland., Lee T; PMI R&D, Philip Morris International Research Laboratories Pte. Ltd, Science Park II, Singapore, 117406, Singapore., Wong SK; PMI R&D, Philip Morris International Research Laboratories Pte. Ltd, Science Park II, Singapore, 117406, Singapore., Lavrynenko O; PMI R&D, Philip Morris Products S.A, Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland., Merg C; PMI R&D, Philip Morris Products S.A, Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland., Corciulo M; PMI R&D, Philip Morris Products S.A, Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland., Simicevic J; PMI R&D, Philip Morris Products S.A, Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland., Auberson M; PMI R&D, Philip Morris Products S.A, Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland., Peric D; PMI R&D, Philip Morris Products S.A, Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland., Dulize R; PMI R&D, Philip Morris Products S.A, Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland., Bornand D; PMI R&D, Philip Morris Products S.A, Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland., Loh GJ; PMI R&D, Philip Morris International Research Laboratories Pte. Ltd, Science Park II, Singapore, 117406, Singapore., Lee KM; Altria Client Services LLC, 601 East Jackson Street, Richmond, VA, 23219, USA., Zhang J; Altria Client Services LLC, 601 East Jackson Street, Richmond, VA, 23219, USA., Miller JH 4th; Altria Client Services LLC, 601 East Jackson Street, Richmond, VA, 23219, USA., Schlage WK; Max-Baermann-Str. 21, 51429, Bergisch Gladbach, Germany., Guedj E; PMI R&D, Philip Morris Products S.A, Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland., Schneider T; PMI R&D, Philip Morris Products S.A, Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland., Phillips B; PMI R&D, Philip Morris International Research Laboratories Pte. Ltd, Science Park II, Singapore, 117406, Singapore., Leroy P; PMI R&D, Philip Morris Products S.A, Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland., Choukrallah MA; PMI R&D, Philip Morris Products S.A, Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland., Sierro N; PMI R&D, Philip Morris Products S.A, Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland., Buettner A; Histovia GmbH, Schöne Aussicht 5, 51491, Overath, Germany., Xiang Y; PMI R&D, Philip Morris Products S.A, Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland., Kuczaj A; PMI R&D, Philip Morris Products S.A, Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland., Ivanov NV; PMI R&D, Philip Morris Products S.A, Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland., Luettich K; PMI R&D, Philip Morris Products S.A, Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland., Vanscheeuwijck P; PMI R&D, Philip Morris Products S.A, Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland., Peitsch MC; PMI R&D, Philip Morris Products S.A, Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland., Hoeng J; PMI R&D, Philip Morris Products S.A, Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland.

Publikováno v: Archives of toxicology [Arch Toxicol] 2021 May; Vol. 95 (5), pp. 1805-1829. Date of Electronic Publication: 2021 May 07.

Direct analysis of dried blood spots by in-line desorption combined with high-resolution chromatography and mass spectrometry for quantification of maple syrup urine disease biomarkers leucine and isoleucine.

Autor: Miller JH 4th; Department of Pharmaceutics, Virginia Commonwealth University Medical Center, PO Box 980533, Richmond, VA 23298-0533, USA. millerjh@vcu.edu, Poston PA, Karnes HT

Publikováno v: Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2011 Apr; Vol. 400 (1), pp. 237-44. Date of Electronic Publication: 2011 Feb 18.