Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Mille Kolind"'
Autor:
Nikita Deo, David G. Little, Jad El-Hoss, Aaron Schindeler, Lauren Peacock, Mille Kolind, Kathy Mikulec
Publikováno v:
Journal of Applied Biomedicine. 16:350-357
Tibial pseudarthrosis often features deficient bone formation, excessive bone resorption, and extensive pathological fibrosis, particularly in individuals with Neurofibromatosis type I (NF1). It was hypothesized that overactive NF1-Ras-JNK signalling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::301440ed6a962364113f9b1f9f01d54b
https://doi.org/10.1016/j.jab.2018.01.006
https://doi.org/10.1016/j.jab.2018.01.006
Autor:
Brya G. Matthews, Aaron Schindeler, Kathy Mikulec, Alastair Aiken, Mille Kolind, David G. Little, Ivo Kalajzic, Justin D. Bobyn
Publikováno v:
Bone. 81:53-59
To better understand the relative contributions of mesenchymal and endothelial progenitor cells to rhBMP-2 induced bone formation, we examined the distribution of lineage-labeled cells in Tie2-Cre:Ai9 and αSMA-creERT2:Col2.3-GFP:Ai9 reporter mice. E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11f645db48cefeaeb233217230426b3a
https://doi.org/10.1016/j.bone.2015.06.023
https://doi.org/10.1016/j.bone.2015.06.023
Autor:
Christopher J. Jackson, Meilang Xue, Mille Kolind, Aaron Schindeler, Tegan L. Cheng, Kaitlin Shen, Ciara M. Murphy, David G. Little, Kathy Mikulec, Lauren Peacock, Sang-Youel Park, Ben Chan
Publikováno v:
Journal of Orthopaedic Research. 32:1549-1556
Activated Protein C (APC) is an anticoagulant with strong cytoprotective properties that has been shown to promote wound healing. In this study APC was investigated for its potential orthopedic application using a Bone Morphogenetic Protein 2 (rhBMP-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2479114b2d26de72b0c31776231471c0
https://doi.org/10.1002/jor.22726
https://doi.org/10.1002/jor.22726
Autor:
Christopher B. Little, Aaron Schindeler, David G. Little, Nikita Deo, Kathy Mikulec, Michelle M. McDonald, Mille Kolind, Miriam T. Jackson, Jad El-Hoss
Publikováno v:
Bone. 59:151-161
MEK inhibitors (MEKi) PD0325901 and AZD6244 (Selumetinib) are drugs currently under clinical investigation for cancer treatment, however the Ras-MAPK pathway is also an important mediator of normal bone cell differentiation and function. In this stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a508389756df756769d4bb9f9d417f16
https://doi.org/10.1016/j.bone.2013.11.013
https://doi.org/10.1016/j.bone.2013.11.013
Publikováno v:
Cellular Reprogramming. 15:101-106
Epithelial-to-mesenchymal transition (EMT) and endothelial-to-mesenchymal transition (EndMT) describe complex changes in progenitor lineage, cell morphology, and gene expression. Stimulated by environmental cues, these cellular transitions are essent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22082597f16b08cd9e3fbab8b4189d89
https://doi.org/10.1089/cell.2012.0054
https://doi.org/10.1089/cell.2012.0054
Publikováno v:
Journal of Biotechnology. 151:357-362
In vivo, clotting Factor VIII (FVIII) circulates in plasma bound to von Willebrand factor (vWF), and the vWF:FVIII complex prevents binding of FVIII to phosphatidylserine (PS). Activation of FVIII by thrombin releases FVIII from vWF, and subsequently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::457a61a7d855cbd443a61ac5ea9d25d1
https://doi.org/10.1016/j.jbiotec.2010.12.019
https://doi.org/10.1016/j.jbiotec.2010.12.019
Autor:
Kathy Mikulec, Laurence C. Cantrill, Matthew A. Summers, David G. Little, Till Seime, Mille Kolind, Aaron Schindeler
Publikováno v:
Development, growthdifferentiation. 57(1)
Mouse models incorporating inducible Cre-ERT2/LoxP recombination coupled with sensitive fluorescent reporter lines are being increasingly used to track cell lineages in vivo. In this study we use two inducible reporter strains, Ai9iCol2a1 (Ai9×Col2a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de0c689b6ef51d79329190451eb45cc6
https://pubmed.ncbi.nlm.nih.gov/25389084
https://pubmed.ncbi.nlm.nih.gov/25389084
Autor:
Kaitlin, Shen, Ciara M, Murphy, Ben, Chan, Mille, Kolind, Tegan L, Cheng, Kathy, Mikulec, Lauren, Peacock, Meilang, Xue, Sang-Youel, Park, David G, Little, Chris J, Jackson, Aaron, Schindeler
Publikováno v:
Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 32(12)
Activated Protein C (APC) is an anticoagulant with strong cytoprotective properties that has been shown to promote wound healing. In this study APC was investigated for its potential orthopedic application using a Bone Morphogenetic Protein 2 (rhBMP-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e1876c4c0500a946e5047e7e4f1de9c9
https://pubmed.ncbi.nlm.nih.gov/25224138
https://pubmed.ncbi.nlm.nih.gov/25224138
Autor:
Mille Kolind, Peder Lisby Nørby, Laust Bruun Johnsen, Thomas Veje Flintegaard, Martin W. Berchtold
Publikováno v:
Journal of biotechnology. 147(3-4)
Factor VIII (FVIII) is an important protein in the blood coagulation cascade and dysfunction or deficiency of FVIII causes haemophilia A. Replacement therapy with exogenous recombinant FVIII (rFVIII) works as a substitute for the missing or non-funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99587549f0a28786839076afbc9ce178
https://pubmed.ncbi.nlm.nih.gov/20438774
https://pubmed.ncbi.nlm.nih.gov/20438774