Structure-Property Optimization of a Series of Imidazopyridines for Visceral Leishmaniasis.

Autor: Dichiara M; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States., Simpson QJ; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States., Quotadamo A; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States., Jalani HB; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States., Huang AX; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States., Millard CC; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States., Klug DM; School of Pharmacy, University College London, London WC1N 1AX, U.K., Tse EG; School of Pharmacy, University College London, London WC1N 1AX, U.K., Todd MH; School of Pharmacy, University College London, London WC1N 1AX, U.K., Silva DG; School of Pharmacy, University College London, London WC1N 1AX, U.K.; School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo 14040-903, Brazil., da Silva Emery F; School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo 14040-903, Brazil., Carlson JE; Rilas Technologies, Inc, 150-W New Boston Street, Woburn, Massachusetts 01801, United States., Zheng SL; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, United States., Vleminckx M; Laboratory of Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, 2610 Wilrijk, Belgium., Matheeussen A; Laboratory of Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, 2610 Wilrijk, Belgium., Caljon G; Laboratory of Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, 2610 Wilrijk, Belgium., Pollastri MP; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States., Sjö P; Drugs for Neglected Diseases Initiative, 15 Chemin Camille Vidart, Geneva 1202, Switzerland., Perry B; Drugs for Neglected Diseases Initiative, 15 Chemin Camille Vidart, Geneva 1202, Switzerland., Ferrins L; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States.

Publikováno v: ACS infectious diseases [ACS Infect Dis] 2023 Aug 11; Vol. 9 (8), pp. 1470-1487. Date of Electronic Publication: 2023 Jul 07.