Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Millar Whalley"'
Autor:
Michael D. Macklin, Darrilyn G. Fraser, George P. Allen, William F. Swain, D. Paul Lunn, J. Millar Whalley, Gisela Soboll, Mathew T. Koen
Publikováno v:
Journal of General Virology. 84:2625-2634
Equine herpesvirus-1 (EHV-1) causes serious disease in horses throughout the world, despite the frequent use of vaccines. CTLs are thought to be critical for protection from primary and reactivating latent EHV-1 infections. However, the antigen-speci
Publikováno v:
Virus Research. 79:125-135
Equine herpesvirus 1 glycoprotein D (EHV-1 gD) has been shown in mouse models and in the natural host to have potential as a subunit vaccine, using various expression systems that included Escherichia coli , baculovirus and plasmid DNA. With the aim
Publikováno v:
Veterinary Microbiology. 76:211-220
DNA-mediated immunization was assessed in a murine model of equine herpesvirus 1 (EHV-1) abortion. Whilst there are differences between the model and natural infection in the horse, literature suggests that EHV-1 infection of pregnant mice can be use
Publikováno v:
Veterinary Microbiology. 76:117-127
We have shown previously that equine herpesvirus 1 (EHV-1) glycoprotein D (gD) DNA elicited protective immune responses against EHV-1 challenge in murine respiratory and abortion models of EHV-1 disease. In this study, 20 horses, all with pre-existin
Publikováno v:
Veterinary Microbiology. 61:261-278
Baculovirus-expressed glycoproteins of EHV-1 gB, gC and gD alone or in combination evoked antibody responses and protected vaccinated mice against a challenge with EHV-1. gB, gD, gB + gC, gB + gD and gC + gD elicited very high levels of ELISA antibod
Autor:
J. Millar Whalley, D. Paul Lunn, Katharine F. Lunn, Stephen B. Hussey, Gisela Soboll, Cormac C. Breathnach, Rodney Clark
Publikováno v:
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc. 18(4)
Equine herpesvirus-1 (EHV-1) infection is common in young horses throughout the world, resulting in respiratory disease, epidemic abortion, sporadic myelitis, or latent infections. To improve on conventional diagnostic tests for EHV-1, a real-time po
Publikováno v:
Australian veterinary journal. 81(5)
Objective To examine the prevalence of equine herpesvirus 1 antibody in mares and foals on a large Hunter Valley Thoroughbred stud farm in New South Wales before and after the introduction of an inactivated whole virus vaccine. Design Cross-sectional
Autor:
J. Millar Whalley, Christopher W. Bell
Publikováno v:
Virus genes. 7(3)
The genome of equine herpesvirus-1 (EHV-1) contained three open reading frames (ORFs) in a 3.9 kbp BamHI-SmaI fragment at 0.38-0.41 map units in the long unique region. The most 5' ORF encoded the carboxy terminus of a protein with 45-55 percent amin
Autor:
Duncan Craven, Martin Elphinstone, Lisa Wiley, Graham Robertson, Millar Whalley, Christopher W. Bell, Daria N. Love
Publikováno v:
Virus genes. 5(4)
A homologue of the herpes simplex virus (HSV) glycoprotein D gene has been identified in the genome of equine herpesvirus-1 (EHV-1, equine abortion virus). An open reading frame in the middle of the short unique (US) region is capable of encoding a p
Publikováno v:
Veterinary Microbiology. 56:159