Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Milla R. McLean"'
Autor:
Janice Z. Jia, Carolyn A. Cohen, Haogao Gu, Milla R. McLean, Raghavan Varadarajan, Nisha Bhandari, Malik Peiris, Gabriel M. Leung, Leo L. M. Poon, Tim Tsang, Amy W. Chung, Benjamin J. Cowling, Nancy H. L. Leung, Sophie A. Valkenburg
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Cross-reactive antibodies with Fc receptor (FcR) effector functions may mitigate pandemic virus impact in the absence of neutralizing antibodies. In this exploratory study, we use serum from a randomized placebo-controlled trial of seasonal
Externí odkaz:
https://doaj.org/article/c15b260c86f84dffa03009a6bb0b59de
Autor:
Janice Z. Jia, Carolyn A. Cohen, Haogao Gu, Milla R. McLean, Raghavan Varadarajan, Nisha Bhandari, Malik Peiris, Gabriel M. Leung, Leo L. M. Poon, Tim Tsang, Amy W. Chung, Benjamin J. Cowling, Nancy H. L. Leung, Sophie A. Valkenburg
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/dbcc812df33143d0a5c9724faf5629b8
Autor:
Melissa M. Lemke, Robert M. Theisen, Emily R. Bozich, Milla R. McLean, Christina Y. Lee, Ester Lopez, Supachai Rerks-Ngarm, Punnee Pitisuttithum, Sorachai Nitayaphan, Sven Kratochvil, Bruce D. Wines, P. Mark Hogarth, Stephen J. Kent, Amy W. Chung, Kelly B. Arnold
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Fc-mediated immune functions have been correlated with protection in the RV144 HIV vaccine trial and are important for immunity to a range of pathogens. IgG antibodies (Abs) that form complexes with Fc receptors (FcRs) on innate immune cells can acti
Externí odkaz:
https://doaj.org/article/35b3306aabcb40c09ff91806b53e7bb8
Autor:
Melissa M. Lemke, Milla R. McLean, Christina Y. Lee, Ester Lopez, Emily R. Bozich, Supachai Rerks-Ngarm, Punnee Pitisuttithum, Sorachai Nitayaphan, Sven Kratochvil, Bruce D. Wines, P. Mark Hogarth, Stephen J. Kent, Amy W. Chung, Kelly B. Arnold
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 9, Pp 100386- (2021)
Summary: Immunoglobulin G (IgG) antibodies that activate Fc-mediated immune functions have been correlated with vaccine efficacy, but it is difficult to unravel the relative roles of multiple IgG and Fc receptor (FcR) features that have the capacity
Externí odkaz:
https://doaj.org/article/7ab01d1112034192a941db86e300e132
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Mycobacterium tuberculosis (Mtb) resides in a quarter of the world's population and is the causative agent for tuberculosis (TB), the most common infectious reason of death in humans today. Although cellular immunity has been firmly established in th
Externí odkaz:
https://doaj.org/article/8f000461cea2412b89a46efc34cb65b7
Autor:
Melissa M. Lemke, Robert M. Theisen, Emily R. Bozich, Milla R. McLean, Christina Y. Lee, Ester Lopez, Supachai Rerks-Ngarm, Punnee Pitisuttithum, Sorachai Nitayaphan, Sven Kratochvil, Bruce D. Wines, P. Mark Hogarth, Stephen J. Kent, Amy W. Chung, Kelly B. Arnold
Publikováno v:
Frontiers in immunology. 13
Fc-mediated immune functions have been correlated with protection in the RV144 HIV vaccine trial and are important for immunity to a range of pathogens. IgG antibodies (Abs) that form complexes with Fc receptors (FcRs) on innate immune cells can acti
Autor:
Bruce D. Wines, Kelly B. Arnold, P. Mark Hogarth, Stephen J. Kent, Emily R. Bozich, Punnee Pitisuttithum, Supachai Rerks-Ngarm, Sven Kratochvil, Milla R. McLean, Sorachai Nitayaphan, Christina Lee, Amy W. Chung, Ester Lopez, Melissa M. Lemke
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 9, Pp 100386-(2021)
Cell Reports Medicine
Cell Reports Medicine
Summary Immunoglobulin G (IgG) antibodies that activate Fc-mediated immune functions have been correlated with vaccine efficacy, but it is difficult to unravel the relative roles of multiple IgG and Fc receptor (FcR) features that have the capacity t
Serological and cellular inflammatory signatures in end‐stage kidney disease and latent tuberculosis
Autor:
Joe Bueti, Sandra Kiazyk, Terry B. Ball, Milla R. McLean, Stephen J. Kent, Kathleen M. Wragg, Ester Lopez, Jennifer A Juno, Amy W. Chung
Publikováno v:
Clinical & Translational Immunology
Clinical & Translational Immunology, Vol 10, Iss 11, Pp n/a-n/a (2021)
Clinical & Translational Immunology, Vol 10, Iss 11, Pp n/a-n/a (2021)
Objectives Tuberculosis comorbidity with chronic diseases including diabetes, HIV and chronic kidney disease is of rising concern. In particular, latent tuberculosis infection (LTBI) comorbidity with end‐stage kidney disease (ESKD) is associated wi
Autor:
David A. Cooper, Bruce D. Wines, P.M. Hogarth, Janaki Amin, Sean Emery, Vijaya Madhavi, Matthew S. Parsons, Milla R. McLean, Stephen J. Kent, Ashwini Shete, Anthony D. Kelleher, Manisha Ghate, Archana Kulkarni, Wen Shi Lee, Madhuri Thakar, Anne B. Kristensen
Publikováno v:
JAIDS Journal of Acquired Immune Deficiency Syndromes. 75:345-353
There is growing interest in immune therapies to clear the latent HIV-1 after combination antiretroviral therapy (cART). There is limited information on the effect of cART on antibody-dependent cellular cytotoxicity (ADCC), and no studies have direct
Publikováno v:
Current HIV Research
Background: There is now intense interest in the role of HIV-specific antibodies and the engagement of FcγR functions in the control and prevention of HIV infection. The analyses of the RV144 vaccine trial, natural progression cohorts, and macaque m