Dissecting the role of Amerindian genetic ancestry and the ApoE ε4 allele on Alzheimer disease in an admixed Peruvian population.

Autor: Marca-Ysabel MV; Neurogenetics Research Center, Instituto Nacional de Ciencias Neurológicas, Lima, Peru., Rajabli F; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA., Cornejo-Olivas M; Neurogenetics Research Center, Instituto Nacional de Ciencias Neurológicas, Lima, Peru; Center for Global Health, Universidad Peruana Cayetano Heredia, Lima, Peru., Whitehead PG; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA., Hofmann NK; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA., Illanes Manrique MZ; Neurogenetics Research Center, Instituto Nacional de Ciencias Neurológicas, Lima, Peru., Veliz Otani DM; Neurogenetics Research Center, Instituto Nacional de Ciencias Neurológicas, Lima, Peru; Fogarty Northern Pacific Global Health Fellows Program, Lima, Peru; Fogarty Interdisciplinary Cerebrovascular Diseases Training Program in South America, Lima, Peru., Milla Neyra AK; Neurogenetics Research Center, Instituto Nacional de Ciencias Neurológicas, Lima, Peru., Castro Suarez S; CBI en Demencias y Enfermedades Desmielinizantes del Sistema Nervioso, Instituto Nacional de Ciencias Neurológicas, Lima, Peru; Atlantic Fellow of Global Brain Health Institute, San Francisco, CA, USA., Meza Vega M; CBI en Demencias y Enfermedades Desmielinizantes del Sistema Nervioso, Instituto Nacional de Ciencias Neurológicas, Lima, Peru; School of Medicine, Universidad Nacional Mayor de San Marcos, Lima, Peru., Adams LD; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA., Mena PR; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA., Rosario I; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA; Dr. John Macdonald Foundation Department of Human Genetics, University of Miami Miller School of Medicine, Miami, FL, USA., Cuccaro ML; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA; Dr. John Macdonald Foundation Department of Human Genetics, University of Miami Miller School of Medicine, Miami, FL, USA., Vance JM; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA; Dr. John Macdonald Foundation Department of Human Genetics, University of Miami Miller School of Medicine, Miami, FL, USA., Beecham GW; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA; Dr. John Macdonald Foundation Department of Human Genetics, University of Miami Miller School of Medicine, Miami, FL, USA., Custodio N; Instituto Peruano de Neurociencias, Lima, Peru., Montesinos R; Instituto Peruano de Neurociencias, Lima, Peru., Mazzetti Soler PE; Neurogenetics Research Center, Instituto Nacional de Ciencias Neurológicas, Lima, Peru; School of Medicine, Universidad Nacional Mayor de San Marcos, Lima, Peru., Pericak-Vance MA; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA; Dr. John Macdonald Foundation Department of Human Genetics, University of Miami Miller School of Medicine, Miami, FL, USA. Electronic address: mpericak@med.miami.edu.

Publikováno v: Neurobiology of aging [Neurobiol Aging] 2021 May; Vol. 101, pp. 298.e11-298.e15. Date of Electronic Publication: 2020 Dec 10.