Výsledky vyhledávání - "Milko Radicioni"

Comparative Bioavailability Study of a New Vitamin D3 Orodispersible Film Versus a Marketed Oral Solution in Healthy Volunteers

Autor: Milko Radicioni, Carol Caverzasio, Stefano Rovati, Andrea Maria Giori, Irma Cupone, Fabio Marra, Giuseppe Mautone

Publikováno v: Clinical Drug Investigation

Background and Objective An orally disintegrating film (ODF) formulation of vitamin D3 that dissolves rapidly in the mouth without drinking or chewing may be a worthwhile alternative to currently available drug products for therapeutic vitamin D supp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d8238907a41e014faefde7b5ab1c7ca
https://doi.org/10.1007/s40261-021-01113-7

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Effect of 3 Single Doses of Trazodone on QTc Interval in Healthy Subjects

Autor: Maria Teresa Rosignoli, Rossella Picollo, Alessandra Del Vecchio, Milko Radicioni, Alessandro Comandini, Valeria Tellone, Patrizia Dragone, Chiara Leuratti, Fabrizio Calisti

Publikováno v: Journal of Clinical Pharmacology

This study evaluated the effect of 3 doses of a trazodone hydrochloride 6% oral drops solution on the QT interval of healthy volunteers. Subjects were randomly assigned to receive a single dose of trazodone 20 mg, 60 mg, and 140 mg, moxifloxacin 400

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e248e1520c574e896bf4c2fd945594dc
http://europepmc.org/articles/PMC7586935

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Randomized Pharmacokinetic Study of a Highly Purified Human Chorionic Gonadotropin and of a Recombinant Human Chorionic Gonadotropin Following Single Subcutaneous Administration in Healthy Women

Autor: Milko Radicioni, Chiara Leuratti, Barbara Cometti

Publikováno v: Clinical drug investigation. 42(3)

Exogenous human chorionic gonadotropin (hCG) acts on the final phase of the follicle maturation. ChoriomonIn this randomized, two-way cross-over study, 26 healthy women received a single dose of ChoriomonSerum hCG concentrations increased rapidly wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7745ce007da3ed89c66e896f5b7a25a1
https://pubmed.ncbi.nlm.nih.gov/35137345

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Pharmacokinetics and Safety of a Diclofenac Sodium 75 mg/1 mL Solution (Akis®/Dicloin®) Administered as a Single Intravenous Bolus Injection in Healthy Men and Women

Autor: Chiara Leuratti, Matteo Rossini, Valeria Frangione, Stefano Rovati, Milko Radicioni, Luca Loprete

Publikováno v: European Journal of Drug Metabolism and Pharmacokinetics. 44:681-689

A 1-mL aqueous solution for parenteral injection containing diclofenac sodium and hydroxypropyl-β-cyclodextrin, presently on the market for intramuscular and subcutaneous administration (Akis®/Dicloin®), was further developed for intravenous (i.v.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8d5274e388b2e9ca6b8b893d69a8486c
https://doi.org/10.1007/s13318-019-00558-8

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Survival of L. casei DG® (Lactobacillus paracasei CNCMI1572) in the gastrointestinal tract of a healthy paediatric population

Autor: Simone Guglielmetti, Walter Fiore, Milko Radicioni, Ranjan Koirala, Chiara Leuratti, Stefania Arioli

Publikováno v: European Journal of Nutrition. 58:3161-3170

Ability to survive the digestive process is a major factor in determining the effectiveness of a probiotic. In this study, the ability of the probiotic L. casei DG® (Lactobacillus paracasei CNCMI1572) to survive gastrointestinal transit in healthy c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d2e95ff37e566d747171aaf1663c880c
https://doi.org/10.1007/s00394-018-1860-5

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Pharmacokinetics and Safety of Rifamycin SV after Single and Multiple Doses of MMX® Modified Release Tablets in Healthy Male and Female Volunteers

Autor: Angelo Vaccani, Alessandro Mazzetti, Milko Radicioni, Andrea F. D. Di Stefano, Luigi Maria Longo, Luigi Moro

Publikováno v: Antibiotics, Vol 10, Iss 167, p 167 (2021)
Antibiotics
Volume 10
Issue 2

The primary objective of this single- and multiple-dose pharmacokinetic study was the investigation of rifamycin SV’s pharmacokinetic profile in plasma and urine. All the 18 enrolled healthy men and post-menopausal women received modified release t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b9ef4534110ca1827e0a433c33c0ba3
https://www.mdpi.com/2079-6382/10/2/167

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Pharmacokinetics and Safety of Single and Multiple Doses of Oral N-Acetylcysteine in Healthy Chinese and Caucasian Volunteers: An Open-Label, Phase I Clinical Study

Autor: Alberto Papi, Milko Radicioni, Andrea F. D. Di Stefano

Publikováno v: Advances in Therapy

Introduction Few studies have evaluated whether the pharmacokinetics of N-acetyl-cysteine (NAC) are different in Chinese and Caucasian individuals. Methods This single- and multiple-dose, single-centre, open-label, phase I clinical study was conducte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab3af25b45c530960452c472fd64f2c1
https://pubmed.ncbi.nlm.nih.gov/33146843

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Phase I Study in Healthy Women of a Novel Antimycotic Vaginal Ovule Combining Econazole and Benzydamine

Autor: A. Vaccani, R Picollo, A F D Di Stefano, Enrica Salvatori, M T Rosignoli, S Olivieri, F Pelacchi, A Comandini, G Bovi, Milko Radicioni, Francesca Focanti, Giorgio Caccia

Publikováno v: Infectious Diseases in Obstetrics and Gynecology, Vol 2020 (2020)
Infectious Diseases in Obstetrics and Gynecology

Purpose. A novel fixed-dose combination of 150 mg of econazole with 6 mg of benzydamine formulated in vaginal ovules was investigated in a randomised, double-blind, four-parallel group, tolerability, and pharmacokinetic Phase I study in healthy women

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17e3537e9cbc5fb20edff108c51eb8e4
https://doaj.org/article/3c1c68baad9749f29151aebdaa2ba5fa

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Pharmacokinetics of a Novel Sildenafil Orodispersible Film Administered by the Supralingual and the Sublingual Route to Healthy Men

Autor: Valeria Frangione, Chiara Leuratti, Luca Loprete, Milko Radicioni

Publikováno v: Clinical Drug Investigation

Background Sildenafil was the first selective drug available on the market as oral therapy for erectile dysfunction (ED). A novel sildenafil orodispersible film (ODF) for ED treatment, containing sildenafil citrate, has recently been marketed. Object

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9c8a3f74a105480cf310d19dd875b4a
https://doi.org/10.1007/s40261-018-0665-x

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Bioequivalence study of a new sildenafil 100 mg orodispersible film compared to the conventional film-coated 100 mg tablet administered to healthy male volunteers

Autor: Valeria Frangione, Milko Radicioni, Irma Elisa Cupone, Stefano Rovati, Chiara Castiglioni, Andrea Giori

Publikováno v: Drug Design, Development and Therapy

Milko Radicioni,1 Chiara Castiglioni,1 Andrea Giori,2 Irma Cupone,3 Valeria Frangione,4 Stefano Rovati4 1CROSS Research S.A., Phase I Unit, Arzo, Switzerland; 2IBSA Farmaceutici Italia, Lodi, Italy; 3Bouty S.p.A., Strada Padana Superiore, Cassina De�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f711e9906e43311a14d6c158eef8a035
https://doi.org/10.2147/dddt.s124034

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