Výsledky vyhledávání - "Miljana Nenkov"

Fatty acid metabolism and acyl-CoA synthetases in the liver-gut axis

Autor: Yunxia Ma, Elke Kaemmerer, Nikolaus Gassler, Adrian T. Press, Miljana Nenkov, Yuan Chen

Publikováno v: World Journal of Hepatology

Fatty acids are energy substrates and cell components which participate in regulating signal transduction, transcription factor activity and secretion of bioactive lipid mediators. The acyl-CoA synthetases (ACSs) family containing 26 family members e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0534640b4d287f35cd24b297a4841ba
http://europepmc.org/articles/PMC8637682

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Tumor-Intrinsic PD-L1 Exerts an Oncogenic Function through the Activation of the Wnt/β-Catenin Pathway in Human Non-Small Cell Lung Cancer

Autor: Chen, Yunxia Ma, Rumyana Marinkova, Miljana Nenkov, Lai Jin, Otmar Huber, Jürgen Sonnemann, Natália Peca, Nikolaus Gaßler, Yuan

Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 19; Pages: 11031

Programmed death ligand 1 (PD-L1) strongly inhibits T cell activation, thereby aiding tumors in escaping the immune response. PD-L1 inhibitors have proven to be effective in the treatment of different types of cancer, including non-small cell lung ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=multidiscipl::6b49039a055c23cd481b8453c257de3e

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Tumor-Intrinsic PD-L1 Exerts an Oncogenic Function through the Activation of the Wnt/β-Catenin Pathway in Human Non-Small Cell Lung Cancer

Autor: Yunxia, Ma, Rumyana, Marinkova, Miljana, Nenkov, Lai, Jin, Otmar, Huber, Jürgen, Sonnemann, Natália, Peca, Nikolaus, Gaßler, Yuan, Chen

Publikováno v: International journal of molecular sciences. 23(19)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d7bb5a16014cbee9463c71ba2d9de02b
https://pubmed.ncbi.nlm.nih.gov/36232331

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Tumor-derived exosomes: Key players in non-small cell lung cancer metastasis and their implication for targeted therapy

Autor: Maryam Noor Rizwan, Yunxia Ma, Miljana Nenkov, Lai Jin, Desiree Charlotte Schröder, Martin Westermann, Nikolaus Gaßler, Yuan Chen

Publikováno v: Molecular carcinogenesisREFERENCES. 61(3)

Exosomes represent extracellular vesicles of endocytic origin ranging from 30 to 100 nm that are released by most of eukaryotic cells and can be found in body fluids. These vesicles in carrying DNA, RNA, microRNA (miRNA), Long noncoding RNA, proteins

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4454d3a77f72fff2b0626c27349c8ab3
https://pubmed.ncbi.nlm.nih.gov/34897815

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Metabolic Reprogramming of Colorectal Cancer Cells and the Microenvironment: Implication for Therapy

Autor: Miljana, Nenkov, Yunxia, Ma, Nikolaus, Gaßler, Yuan, Chen

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 6262, p 6262 (2021)
International Journal of Molecular Sciences

Colorectal carcinoma (CRC) is one of the most frequently diagnosed carcinomas and one of the leading causes of cancer-related death worldwide. Metabolic reprogramming, a hallmark of cancer, is closely related to the initiation and progression of carc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::1ebaf3744d0b0012387ce2749c01c0d2
https://www.mdpi.com/1422-0067/22/12/6262

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Epithelial Membrane Protein 2 Suppresses Non-Small Cell Lung Cancer Cell Growth by Inhibition of MAPK Pathway

Autor: Yunxia Ma, Desiree Charlotte Schröder, Miljana Nenkov, Maryam Noor Rizwan, Mohamed Abubrig, Jürgen Sonnemann, José M. Murrieta-Coxca, Diana M. Morales-Prieto, Martin Westermann, Nikolaus Gaßler, Yuan Chen

Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 6
International Journal of Molecular Sciences, Vol 22, Iss 2944, p 2944 (2021)

Epithelial membrane proteins (EMP1-3) are involved in epithelial differentiation and carcinogenesis. Dysregulated expression of EMP2 was observed in various cancers, but its role in human lung cancer is not yet clarified. In this study, we analyzed t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d394fb4cb90f906273488802aaee92e4
http://europepmc.org/articles/PMC7999101

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Growth inhibitory role of the p53 activator SCH 529074 in non‑small cell lung cancer cells expressing mutant p53

Autor: Iver Petersen, Daniela Haase, Yong Li, Yunxia Ma, Yuan Chen, Miljana Nenkov, Zhong-Wei Zhou, Guanghua Lu

Publikováno v: Oncology reports. 43(6)

Mutations of p53 occur in approximately 50% of advanced non‑small cell lung cancer (NSCLC) cases, leading to loss of tumor suppressive function and/or gain of p53 oncogenic activity. Reactivation of mutant p53 and consequently induction of apoptosi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::128687fb3c8591a4299dc78616891cc7
https://pubmed.ncbi.nlm.nih.gov/32186773

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The Clinical Influence of Autophagy-Associated Proteins on Human Lung Cancer

Autor: Kai Leonie Schnitzler, Yunxia Ma, Bernhard Theis, Yuan Chen, Miljana Nenkov, Iver Petersen

Publikováno v: Disease Markers
Disease Markers, Vol 2018 (2018)

Exploitation of autophagy might potentially improve therapeutic strategy. Here, we analyzed the protein expression of autophagy-associated genes including LC3A, LC3B, Beclin-1, p62, and Atg5 in 88–131 primary lung tumors by immunohistochemistry (IH

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c350ddfcd3672e48f7473448e9ce86f
https://pubmed.ncbi.nlm.nih.gov/29545906

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