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pro vyhledávání: '"Miljan Stupar"'
Autor:
Miljan Stupar, Lendl Tan, Edward D. Kerr, Christopher J. De Voss, Brian M. Forde, Benjamin L. Schulz, Nicholas P. West
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract The ability of Mycobacterium tuberculosis (Mtb) to persist in the host complicates and prolongs tuberculosis (TB) patient chemotherapy. Here we demonstrate that a neglected two-component system (TCS) of Mtb, TcrXY, is an autoregulated acid-s
Externí odkaz:
https://doaj.org/article/54acaefe3dc54bb8a1d52f6454f667e1
Autor:
Miljan Stupar, Lendl Tan, Edward Kerr, Christopher De Voss, Brian Forde, Benjamin Schulz, Nicholas P. West
The ability of Mycobacterium tuberculosis (Mtb) to persist in the host complicates and prolongs tuberculosis (TB) patient chemotherapy. Here we demonstrate that a neglected two-component system (TCS) of Mtb, TcrXY, is an autoregulated acid-sensing TC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f1c3f06dfae1682986490426443ffbe
https://doi.org/10.21203/rs.3.rs-2847166/v1
https://doi.org/10.21203/rs.3.rs-2847166/v1
Publikováno v:
Molecular Microbiology. 117:973-985
Intracellular bacterial pathogens such as Mycobacterium tuberculosis are remarkably adept at surviving within a host, employing a variety of mechanisms to counteract host defenses and establish a protected niche. Constant surveying of the environment