Increased prevalence of hybrid epithelial/mesenchymal state and enhanced phenotypic heterogeneity in basal breast cancer

Autor: Sahoo, Sarthak, Ramu, Soundharya, Nair, Madhumathy G., Pillai, Maalavika, San Juan, Beatriz P., Milioli, Heloisa Zaccaron, Mandal, Susmita, Naidu, Chandrakala M., Mavatkar, Apoorva D., Subramaniam, Harini, Neogi, Arpita G., Chaffer, Christine L., Prabhu, Jyothi S., Somarelli, Jason A., Jolly, Mohit Kumar

Publikováno v: In iScience 19 July 2024 27(7)

Multi-modal transcriptomic analysis unravels enrichment of hybrid epithelial/mesenchymal state and enhanced phenotypic heterogeneity in basal breast cancer.

Autor: Sahoo S; Department of Bioengineering, Indian Institute of Science, Bangalore, 560012, India., Ramu S; Department of Bioengineering, Indian Institute of Science, Bangalore, 560012, India., Nair MG; Division of Molecular Medicine, St. John's Research Institute, St. John's Medical College, Bangalore, 560012, India., Pillai M; Department of Bioengineering, Indian Institute of Science, Bangalore, 560012, India.; Current affiliation: Feinberg School of Medicine, Northwestern University, Chicago, 60611, USA., San Juan BP; Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia., Milioli HZ; Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia., Mandal S; Department of Bioengineering, Indian Institute of Science, Bangalore, 560012, India., Naidu CM; Division of Molecular Medicine, St. John's Research Institute, St. John's Medical College, Bangalore, 560012, India., Mavatkar AD; Division of Molecular Medicine, St. John's Research Institute, St. John's Medical College, Bangalore, 560012, India., Subramaniam H; Department of Bioengineering, Indian Institute of Science, Bangalore, 560012, India., Neogi AG; Department of Bioengineering, Indian Institute of Science, Bangalore, 560012, India., Chaffer CL; Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia.; University of New South Wales, UNSW Medicine, UNSW Sydney, NSW, 2052, Australia., Prabhu JS; Division of Molecular Medicine, St. John's Research Institute, St. John's Medical College, Bangalore, 560012, India., Somarelli JA; Department of Medicine, Duke University, Durham, NC 27708, USA., Jolly MK; Department of Bioengineering, Indian Institute of Science, Bangalore, 560012, India.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Oct 02. Date of Electronic Publication: 2023 Oct 02.