Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Milinda E. James"'
Autor:
Nyles W. Charon, Michael R. Miller, Kai Zhang, Michael J. Lynch, Milinda E. James, Chunhao Li, Sheng Zhang, Brian R. Crane
Publikováno v:
Nature chemical biology
The flagellar hook protein FlgE from spirochaete bacteria self-catalyzes the formation of an unusual inter-subunit lysinoalanine (Lal) crosslink that is critical for cell motility. Unlike other known examples of Lal biosynthesis, conserved cysteine a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1acb1a864db6ff29f66337cfd39c953
https://doi.org/10.1038/s41589-019-0341-3
https://doi.org/10.1038/s41589-019-0341-3
Autor:
Bo Hu, Jun Liu, Nyles W. Charon, Steven J. Norris, Kai Zhang, Kelly A. Miller, Chunhao Li, Milinda E. James, Tristan Boquoi, Xiaowei Zhao, Md. A. Motaleb, Michael D. Manson
Publikováno v:
Proceedings of the National Academy of Sciences. 110:14390-14395
Periplasmic flagella are essential for the distinctive morphology, motility, and infectious life cycle of the Lyme disease spirochete Borrelia burgdorferi . In this study, we genetically trapped intermediates in flagellar assembly and determined the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d98537ed0b79cf4e6fb12733adcfbfd6
https://doi.org/10.1073/pnas.1308306110
https://doi.org/10.1073/pnas.1308306110
Autor:
Jun Liu, Andrew Cockburn, Michael J. Lynch, Brian R. Crane, Jiang Bian, Nyles W. Charon, Chunhao Li, Justin M. Hettick, Patrick S. Callery, Kelly A. Miller, Sheng Zhang, Milinda E. James, Michael R. Miller
Publikováno v:
Nature microbiology
Spirochaetes are bacteria responsible for several serious diseases, including Lyme disease (Borrelia burgdorferi), syphilis (Treponema pallidum) and leptospirosis (Leptospira interrogans), and contribute to periodontal diseases (Treponema denticola)(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4824036316798a95d22ceee2e5ec60a6
https://pubmed.ncbi.nlm.nih.gov/27670124
https://pubmed.ncbi.nlm.nih.gov/27670124
Autor:
Stephanie J. Frisbee, Adam G. Goodwill, Phoebe A. Stapleton, Jefferson C. Frisbee, Milinda E. James
Publikováno v:
Microcirculation. 16:667-684
Objective: The obese Zucker rat (OZR) model of the metabolic syndrome is partly characterized by moderate hypercholesterolemia, in addition to other contributing comorbidities. Previous results suggest that vascular dysfunction in OZR is associated w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87cafe923393c8bd886874f65f729e08
https://doi.org/10.3109/10739680903133722
https://doi.org/10.3109/10739680903133722
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 295:H1522-H1528
This study determined if altered vascular prostacyclin (PGI2) and/or thromboxane A2 (TxA2) production with reduced Po2 contributes to impaired hypoxic dilation of skeletal muscle resistance arterioles of obese Zucker rats (OZRs) versus lean Zucker ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2054b7f582a262e527db72b8564e483
https://doi.org/10.1152/ajpheart.00596.2008
https://doi.org/10.1152/ajpheart.00596.2008
Publikováno v:
Pathophysiology. 15:79-89
One of the most profound challenges facing public health and public health policy in Western society is the increased incidence and prevalence of both overweight and obesity. While this condition can have significant consequences for patient mortalit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4b9a5b0ae243ed07228efd837fa00b4
https://doi.org/10.1016/j.pathophys.2008.04.007
https://doi.org/10.1016/j.pathophys.2008.04.007
Autor:
Phoebe A. Stapleton, Jefferson C. Frisbee, Milinda E. James, Adam G. Goodwill, Robert W. Brock
Publikováno v:
Journal of Inflammation, Vol 7, Iss 1, p 54 (2010)
Journal of Inflammation (London, England)
Journal of Inflammation (London, England)
Hypercholesterolemia is defined as excessively high plasma cholesterol levels, and is a strong risk factor for many negative cardiovascular events. Total cholesterol levels above 200 mg/dl have repeatedly been correlated as an independent risk factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::473e58ccacd22ee07f243a72e7301c9e
https://doi.org/10.1186/1476-9255-7-54
https://doi.org/10.1186/1476-9255-7-54
Autor:
Milinda E. James, Stephanie J. Frisbee, Adam G Goodwill, Jefferson C. Frisbee, Phoebe A. Stapleton
Publikováno v:
The FASEB Journal. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a3be283dc478190277d526151dcaead
https://doi.org/10.1096/fasebj.24.1_supplement.774.19
https://doi.org/10.1096/fasebj.24.1_supplement.774.19
Autor:
Jordan A.L. Beckett, Jefferson C. Frisbee, Phoebe A. Stapleton, Adam G. Goodwill, Milinda E. James, Alexandre d'Audiffret
Publikováno v:
ResearcherID
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c33889ee9c230aa8804683a6dc625648
https://doi.org/10.1096/fasebj.24.1_supplement.1044.3
https://doi.org/10.1096/fasebj.24.1_supplement.1044.3
Autor:
Phoebe A. Stapleton, Adam G. Goodwill, Milinda E. James, Alexandre d'Audiffret, Jefferson C. Frisbee
Genetic familial hypercholesterolemia (FH) and combined hyperlipidemia (FCH) are characterized by elevated plasma low-density lipoprotein (LDL) (FH) and LDL/triglycerides (FCH), with mouse models represented by LDL receptor (LDLR) and apolipoprotein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6df87da33530989d9ec925402ba07fc
https://europepmc.org/articles/PMC2952832/
https://europepmc.org/articles/PMC2952832/
