Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Milind Saudi"'
Autor:
Arthur van Aerschot, Milind Saudi
Publikováno v:
Molecules, Vol 18, Iss 7, Pp 8524-8534 (2013)
Benzhydryl protection of primary and secondary alcohols has been reported previously via reaction with metal alcoholates. Our aim was to find generally useful and very mild conditions for the alcoholic protection and deprotection of nucleosides with
Externí odkaz:
https://doaj.org/article/7a3cb855e1964b21a42a8f36483e3b69
Autor:
Suzanne J.F. Kaptein, Jef Rozenski, Johan Neyts, Mathy Froeyen, Arthur Van Aerschot, Milind Saudi, Akkaladevi Venkatesham
Publikováno v:
European journal of medicinal chemistry. 126
Previous efforts led to dicarboxamide derivatives like 1.3, comprising either an imidazole, pyrazine or fenyl ring as the central scaffold, with many congeners displaying strong inhibitory effects against dengue virus (DENV) in cell-based assays. Fol
Autor:
Suzanne J.F. Kaptein, Arthur Van Aerschot, Johan Neyts, Jef Rozenski, Milind Saudi, Joanna Zmurko
Publikováno v:
European Journal of Medicinal Chemistry; Vol 76
HEALTH FP7 Publications Database
Lirias
HEALTH FP7 Publications Database
Lirias
Several flaviviruses, such as the yellow fever virus and the dengue virus cause severe and potentially lethal infection in man. Following up on our initial hit 3',5'-bistritylated uridine 1, a series of alkylated nucleoside analogues were synthesized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dba22963776f5ded024092a0ecdf0de
https://lirias.kuleuven.be/handle/123456789/443764
https://lirias.kuleuven.be/handle/123456789/443764
Autor:
Tine De Burghgraeve, Grégory Chatelain, Milind Saudi, Jef Rozenski, Johan Neyts, Arthur Van Aerschot, Joanna Zmurko, Yannick Debing
Publikováno v:
European Journal of Medicinal Chemistry; Vol 65
HEALTH FP7 Publications Database
Lirias
HEALTH FP7 Publications Database
Lirias
Following up on a hit that was identified in a large scale cell-based antiviral screening effort, a series of triphenylmethyl alkylated nucleoside analogues were synthesized and evaluated for their in vitro antiviral activities against the dengue vir
Autor:
Suzanne J.F. Kaptein, Jef Rozenski, Patrick Chaltin, Milind Saudi, Johan Neyts, Arnaud Marchand, Bharat Gadakh, Joanna Zmurko, Arthur Van Aerschot
Publikováno v:
European Journal of Medicinal Chemistry
High-throughput screening of a subset of the CD3 chemical library (Centre for Drug Design and Discovery; KU Leuven) provided us with a lead compound 1, displaying low micromolar potency against dengue virus and yellow fever virus. Within a project ai
Autor:
Jef Rozenski, Arthur Van Aerschot, Suzanne J.F. Kaptein, Joanna Zmurko, Johan Neyts, Milind Saudi
Publikováno v:
European Journal of Medicinal Chemistry
BASE (Open Access Aggregator)
Lirias
PubMed Central
BASE (Open Access Aggregator)
Lirias
PubMed Central
The results of a high-throughput screening assay using the dengue virus-2 replicon showed that the imidazole 4,5-dicarboxamide (I45DC) derivative (15a) has a high dengue virus inhibitory activity. Based on 15a as a lead compound, a novel class of bot
Autor:
Saudi, Milind1 milind.saudi@rega.kuleuven.be, van Aerschot, Arthur1 athur.vanaerschot@rega.kuleuven.be
Publikováno v:
Molecules. Jul2013, Vol. 18 Issue 7, p8524-8534. 11p. 3 Diagrams, 4 Charts, 14 Graphs.