Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Milind M. Muley"'
Publikováno v:
Arthritis Research & Therapy, Vol 19, Iss 1, Pp 1-9 (2017)
Abstract Background The endocannabinoid system has been shown to reduce inflammatory flares and pain in rodent models of arthritis. A limitation of endocannabinoids is that they are rapidly denatured by hydrolysing enzymes such as fatty acid amide hy
Externí odkaz:
https://doaj.org/article/a265ad12921b4757aaa752994e7bf3f6
Autor:
Josiane C.S. Mapplebeck, Louis-Etienne Lorenzo, Kwan Yeop Lee, Cédric Gauthier, Milind M. Muley, Yves De Koninck, Steven A. Prescott, Michael W. Salter
Publikováno v:
Cell Reports, Vol 28, Iss 3, Pp 590-596.e4 (2019)
Summary: The behavioral features of neuropathic pain are not sexually dimorphic despite sex differences in the underlying neuroimmune signaling. This raises questions about whether neural processing is comparably altered. Here, we test whether the K+
Externí odkaz:
https://doaj.org/article/aa631a09ebdc4dbaa0b457019ff02ac8
Publikováno v:
Annual Review of Pharmacology and Toxicology. 63:565-583
The study of chronic pain continues to generate ever-increasing numbers of publications, but safe and efficacious treatments for chronic pain remain elusive. Recognition of sex-specific mechanisms underlying chronic pain has resulted in a surge of st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c68b1c4b7083e3267a108dcfaeee3a97
https://doi.org/10.1146/annurev-pharmtox-051421-112259
https://doi.org/10.1146/annurev-pharmtox-051421-112259
Publikováno v:
Pain. 163:e1129-e1144
The dominant view in the field of pain is that peripheral neuropathic pain is driven by microglia in the somatosensory processing region of the spinal dorsal horn. Here, to the contrary, we discovered a form of neuropathic pain that is independent of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::855913ccc097a40fc4ae52b73b7d9e04
https://doi.org/10.1097/j.pain.0000000000002643
https://doi.org/10.1097/j.pain.0000000000002643
Autor:
Shahrzad Ghazisaeidi, Milind M. Muley, YuShan Tu, Mahshad Kolahdouzan, Ameet S. Sengar, Arun K. Ramani, Michael Brudno, Michael W. Salter
Background and Purpose: Chronic pain is a devastating problem affecting 1 in 5 individuals around the globe, with neuropathic pain the most debilitating and poorly treated type of chronic pain. Advances in transcriptomics and data mining have contrib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8511be5eea8a215fde7606cfe1231016
https://doi.org/10.22541/au.166325658.84625800/v1
https://doi.org/10.22541/au.166325658.84625800/v1
Autor:
Milind M. Muley, Patricia R. Souza, Jason J. McDougall, Eugene Krustev, Mauro Perretti, Magdalena Kaneva, Francesco Dell'Accio, Allison Reid
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 35(5)
While new treatments have been developed to control joint disease in rheumatoid arthritis, they are partially effective and do not promote structural repair of cartilage. Following an initial identification of α-1-Antitrypsin (AAT) during the resolu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::297506af45205f3669b7288631c3256a
https://pubmed.ncbi.nlm.nih.gov/33788977
https://pubmed.ncbi.nlm.nih.gov/33788977
Publikováno v:
Neuropeptides. 64:131-135
Neurogenic inflammation is a local inflammatory response that is driven by the peripheral release of neuropeptides from small diameter afferents which occurs in many organs including joints. The knee joint has a rich endocannabinoid system which has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8bd4c161b9c24a06395c2ccf62151a0
https://doi.org/10.1016/j.npep.2016.08.007
https://doi.org/10.1016/j.npep.2016.08.007
Autor:
Shahrzad Ghazisaeidi, Ameet S. Sengar, Michael W. Salter, Rosanna Weksberg, Katherine Halievski, Milind M. Muley, David P. Finn, Sofia Assi, Amy Tu, Parisa Shooshtari, Vivian Wang, Michael Brudno, Arun K. Ramani
Publikováno v:
Canadian Journal of Pain, Vol 0, Iss 0 (2019)
Introduction/Aim: Chronic pain affects 1 in 5 Canadians and costs over $43B annually, yet effective and safe treatment options remain elusive. Recent discoveries have brought to the forefront sex differences in mechanisms of pain as a potential expla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52857980bfa6c5ad51cf2c737d94820b
https://doaj.org/article/6db73026970f4312bb259d80a4c80c5c
https://doaj.org/article/6db73026970f4312bb259d80a4c80c5c
Autor:
Milind M. Muley, Michael W. Salter, Kwan Yeop Lee, Steven A. Prescott, Cédric Gauthier, Louis-Etienne Lorenzo, Yves De Koninck, Josiane C.S. Mapplebeck
Publikováno v:
Cell Reports, Vol 28, Iss 3, Pp 590-596.e4 (2019)
Summary: The behavioral features of neuropathic pain are not sexually dimorphic despite sex differences in the underlying neuroimmune signaling. This raises questions about whether neural processing is comparably altered. Here, we test whether the K+
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed94bcdaecd09719b533c99fcf772b46
https://pubmed.ncbi.nlm.nih.gov/31315039
https://pubmed.ncbi.nlm.nih.gov/31315039
Autor:
Milind M. Muley, Bálint Botz, Allison Reid, Kata Bölcskei, Zsuzsanna Helyes, Jason J. McDougall
Publikováno v:
British Journal of Pharmacology. 173:766-777
Background and Purpose Neutrophil elastase plays a crucial role in arthritis. Here, its potential in triggering joint inflammation and pain was assessed, and whether these effects were mediated by proteinase-activated receptor-2 (PAR2). Experimental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09d465c359ddbcf81baa4a8d6ab0917d
https://doi.org/10.1111/bph.13237
https://doi.org/10.1111/bph.13237