Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Milica Tesic Mark"'
Autor:
Mohsan Saeed, Sebastian Kapell, Nicholas T Hertz, Xianfang Wu, Kierstin Bell, Alison W Ashbrook, Milica Tesic Mark, Henry A Zebroski, Maxwell L Neal, Malin Flodström-Tullberg, Margaret R MacDonald, John D Aitchison, Henrik Molina, Charles M Rice
Publikováno v:
PLoS Pathogens, Vol 16, Iss 9, p e1008927 (2020)
Viruses cleave cellular proteins to remodel the host proteome. The study of these cleavages has revealed mechanisms of immune evasion, resource exploitation, and pathogenesis. However, the full extent of virus-induced proteolysis in infected cells is
Externí odkaz:
https://doaj.org/article/a0af98e83ecb4080aebefd1e79bfc91f
Autor:
Jing Zhou, Alberto Benito-Martin, Jason Mighty, Lynne Chang, Shima Ghoroghi, Hao Wu, Madeline Wong, Sara Guariglia, Petr Baranov, Michael Young, Rajendra Gharbaran, Mark Emerson, Milica Tesic Mark, Henrik Molina, M. Valeria Canto-Soler, Hector Peinado Selgas, Stephen Redenti
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-1 (2018)
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
Externí odkaz:
https://doaj.org/article/13de735e88744d6dbcf461a4f3983b27
Autor:
Etienne Meylan, David R. Jones, Navneet Narula, Jinxiang Dai, Shahin Rafii, Yuan Liu, Henrik Molina, Irene Casanova-Salas, Han Sang Kim, Irina Matei, David J. Pisapia, Alberto Benito-Martin, Quincey LaPlant, Joshua K. Sabari, Milica Tesic Mark, David Lyden, Candia M. Kenific, Daniela Freitas, Sandra J. Shin, Xinran Jiang, Nasser K. Altorki, Yonathan Ararso, Katharine Offer, Paula S. Ginter, Brian D. Dill, Loïc Steiner, Vinagolu K. Rajasekhar, Brunilde Gril, Huajuan Wang, Maria de Sousa, Gonçalo Rodrigues, Chaitanya R. Badwe, Héctor Peinado, Shizhen Emily Wang, Tyler M. Lu, Bruno Costa-Silva, Haiying Zhang, Patricia S. Steeg, Cyrus M. Ghajar, Ayuko Hoshino, Weston Buehring, John H. Healey, Charles M. Rudin, Peter R. Oxley, Linda Bojmar, Ilana Scandariato, Jacqueline Bromberg
Publikováno v:
Nature cell biology, vol 21, iss 11
Nat Cell Biol
Nat Cell Biol
The development of effective therapies against brain metastasis is currently hindered by limitations in our understanding of the molecular mechanisms driving it. Here we define the contributions of tumour-secreted exosomes to brain metastatic coloniz
Autor:
Margaret R. MacDonald, Kierstin L. Bell, Xianfang Wu, John D. Aitchison, Charles M. Rice, Alison W. Ashbrook, Milica Tesic Mark, Henry Zebroski, Malin Flodström-Tullberg, Nicholas T. Hertz, Maxwell Lewis Neal, Mohsan Saeed, Sebastian Kapell, Henrik Molina
Publikováno v:
PLoS Pathogens, Vol 16, Iss 9, p e1008927 (2020)
PLoS Pathogens
PLoS Pathogens
Viruses cleave cellular proteins to remodel the host proteome. The study of these cleavages has revealed mechanisms of immune evasion, resource exploitation, and pathogenesis. However, the full extent of virus-induced proteolysis in infected cells is
Autor:
Lynne Chang, Jing Zhou, Madeline Wong, Michael J. Young, Petr Baranov, Milica Tesic Mark, Shima Ghoroghi, Hector Peinado Selgas, M. Valeria Canto-Soler, Stephen Redenti, Henrik Molina, Hao Wu, Rajendra Gharbaran, Alberto Benito-Martin, Jason Mighty, Mark M. Emerson, Sara R. Guariglia
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-1 (2018)
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
Autor:
Miho Nakajima, Maša Alečković, Linda Bojmar, Avigdor Scherz, Benjamin A. Garcia, Jacqueline Bromberg, Irit Sagi, Pernille Lauritzen, Yuan Liu, Michael F. Berger, Kayleen A. Bailey, Kofi Ennu Gyan, Moshe Oren, Kei Sugiura, Charles M. Rudin, Zoe Posner, Shakeel Modak, Milica Tesic Mark, Joshua S. Jolissant, Irina Matei, Henrik Molina, Constantinos P. Zambirinis, Mark A. LaBarge, G. Praveen Raju, Srikanth R. Ambati, Jeanine Baisch, Mariel Marrano, Tanya M. Trippett, Caitlin Williams, Alexander J. Chou, Ayako Hashimoto, David J. Pisapia, Michele Cioffi, Stephanie Vitolano, Norman J. Lacayo, Yves A. DeClerck, Geraldine P. Wright, Michael A. Hollingsworth, Joe DeStefano, Vinod P. Balachandran, Michael H.A. Roehrl, Mary Petriccione, Mary S. Brady, Kim Kramer, Héctor Peinado, Guillermo García-Santos, David R. Jones, Haiying Zhang, Mina J. Bissell, Jonathan M. Hernandez, Naoko Takahashi, Yonathan Ararso, L. Miles Schaeffer, Daniela Freitas, Enrico Danzer, David P. Kelsen, Ben Z. Stanger, Paul A. Meyers, Stephen S. Roberts, Cyrus M. Ghajar, Angela Di Giannatale, Jack D. Bui, William R. Jarnagin, Virginia Pascual, Eileen M. O'Reilly, Todd E. Heaton, David Lyden, Amber L. Simpson, Michael P. La Quaglia, Arti Shukla, Serena Lucotti, Vinagolu K. Rajasekhar, Amina Ahmed, John H. Healey, Robert E. Schwartz, Candia M. Kenific, Emily K. Slotkin, Laura Nogués, Kristy A. Brown, Søren Heissel, Daniel Diolaiti, Loïc Steiner, Ruth Scherz-Shouval, Yosef Yarden, Theresa C. Vincent, Martin R. Weiser, Fatima Cardoso, Han Sang Kim, Ayuko Hoshino, Huajuan Wang, Sujit Sheth, Fanny A. Pelissier Vatter, Yibin Kang, Maria Donzelli, Laurence Blavier, Benjamin A. Krantz, Alexander E. Davies, Thomas C. Caffrey, Yusuke Ogitani, Cheryl Fischer, Maria de Sousa, Gonçalo Rodrigues, Ellen M. Basu, Weston Buehring, Surinder K. Batra, Maneesh Jain, Diane M. Simeone, Leonard H. Wexler, Alberto Benito-Martin, Yasmin Khakoo, Lee Ganshaw, Katharine Offer, Paul M. Grandgenett, Bruno Costa-Silva, Kevin C. De Braganca, Mahathi Malladi, Ashton Harris
Publikováno v:
Signal Transduction and Targeted Therapy
Cell
Cell
Summary There is an unmet clinical need for improved tissue and liquid biopsy tools for cancer detection. We investigated the proteomic profile of extracellular vesicles and particles (EVPs) in 426 human samples from tissue explants (TEs), plasma, an
Autor:
Hao Wu, Lynne Chang, Henrik Molina, Milica Tesic Mark, Michael J. Young, M. Valeria Canto-Soler, Shima Ghoroghi, Petr Baranov, Rajendra Gharbaran, Jason Mighty, Alberto Benito-Martin, Madeline Wong, Sara R. Guariglia, Jing Zhou, Hector Peinado Selgas, Stephen Redenti, Mark M. Emerson
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Repisalud
Instituto de Salud Carlos III (ISCIII)
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Repisalud
Instituto de Salud Carlos III (ISCIII)
A range of cell types, including embryonic stem cells, neurons and astrocytes have been shown to release extracellular vesicles (EVs) containing molecular cargo. Across cell types, EVs facilitate transfer of mRNA, microRNA and proteins between cells.
Autor:
Mithat Gonen, Milica Tesic Mark, Ronald P. DeMatteo, Michael I. D’Angelica, Gokce Askan, T. Peter Kingham, Olca Basturk, Henrik Molina, Bruno Costa-Silva, Constantinos P. Zambirinis, Jonathan M. Hernandez, William R. Jarnagin, Linda Bojmar, David Lyden, Peter J. Allen, Elke J. A. H. van Beek, Alexandre Doussot, Jian Zheng
Background Exosomes are nanovesicles that have been shown to mediate carcinogenesis in pancreatic ductal adenocarcinoma (PDAC). Given the direct communication of pancreatic duct fluid with the tumor and its relative accessibility, we aimed to determi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::008f77154cb09a219404989d7ef9bd99
https://europepmc.org/articles/PMC6779041/
https://europepmc.org/articles/PMC6779041/
Autor:
Gregg G. Gundersen, Koji Nakanishi, Doina M. Mihai, Francesca Bartolini, Akira Kawamura, Ilyas Washington, Milica Tesic Mark
Ginkgolides are terpene trilactones in Ginkgo biloba, a popular medicinal herb for memory disorders. Although ginkgolides are known for various neurobiological effects, their macromolecular target in brain is unknown. In this work, we employed benzop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93bbe4500cf9b0aa723c4f35e45ac6a4
https://europepmc.org/articles/PMC5378617/
https://europepmc.org/articles/PMC5378617/
Autor:
Mary Sue Brady, Han Sang Kim, Miho Nakajima, Ayuko Hoshino, Navid Paknejad, Linda Bojmar, Milica Tesic Mark, Kristina I. Fabijanic, Celso A. Reis, Justin Fang, David Lyden, André M. N. Silva, Alberto Benito Martin, Robert E. Schwartz, Hugo Osório, Haiying Zhang, Ashish Massey, Jacqueline Bromberg, Héctor Peinado, Sham Rampersaud, Anders P. Mutvei, Juan Pablo Jimenez, Zhong Li, Giuseppe Galletti, Haiyan Chen, Huajuan Wang, John Blenis, Katia Manova-Todorova, Irina Matei, Ana Magalhães, Weston Buehring, José Alexandre Ferreira, Matthew Brendel, Candia M. Kenific, Pasquale Sansone, Leona Cohen-Gould, Juan R. Cubillos-Ruiz, Henrik Molina, Hiroshi Matsui, Ana Maria Cuervo, Paraskevi Giannakakou, Daniela Freitas
Publikováno v:
Nature cell biology. 20(3)
The heterogeneity of exosomal populations has hindered our understanding of their biogenesis, molecular composition, biodistribution and functions. By employing asymmetric flow field-flow fractionation (AF4), we identified two exosome subpopulations