Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Milestone in Physiology"'
Autor:
Baron Chanda, John B Cowgill
Publikováno v:
The Journal of General Physiology
Cowgill and Chanda discuss the importance of voltage clamp fluorometry to the functional interpretation of ion channel and transporter structures.
Key advances in single particle cryo-EM methods in the past decade have ushered in a resolution re
Key advances in single particle cryo-EM methods in the past decade have ushered in a resolution re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6501f5af09644b83bcde396b569b58b0
https://doi.org/10.1085/jgp.201912372
https://doi.org/10.1085/jgp.201912372
Autor:
Richard L. Moss, R. John Solaro
Publikováno v:
The Journal of General Physiology
Introduction There are many notable examples of physiological processes for which current mechanistic understanding seems obvious but in past times were unknown or at best faintly suggested by isolated correlative observations. The systematic determi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9470255bb8d139a55047c2522cb583ef
http://europepmc.org/articles/PMC6504292
http://europepmc.org/articles/PMC6504292
Autor:
Harris, Andrew L.
Publikováno v:
The Journal of General Physiology
Harris explores the development of our current understanding of electrical coupling between cells and the channels that mediate it, highlighting the contributions of the Journal of General Physiology.
As the physiology of synapses began to be ex
As the physiology of synapses began to be ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6033e0a7b9e8adc6c168683f517398ce
https://doi.org/10.1085/jgp.201812203
https://doi.org/10.1085/jgp.201812203
Carriers, exchangers, and cotransporters in the first 100 years of the Journal of General Physiology
Autor:
Jennings, Michael L.
Publikováno v:
The Journal of General Physiology
Jennings reviews the many contributions of JGP articles to our current understanding of solute transporter mechanisms.
Transporters, pumps, and channels are proteins that catalyze the movement of solutes across membranes. The single-solute carri
Transporters, pumps, and channels are proteins that catalyze the movement of solutes across membranes. The single-solute carri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74a1d0820c56bc9cc9f3d1fac22a9c4c
https://doi.org/10.1085/jgp.201812078
https://doi.org/10.1085/jgp.201812078
Autor:
Eduardo Ríos
Publikováno v:
The Journal of General Physiology
Ríos relates the history of Ca2+-induced Ca2+ release and how its contribution to skeletal muscle physiology was determined.
Ryanodine-sensitive intracellular Ca2+ channels (RyRs) open upon binding Ca2+ at cytosolic-facing sites. This results i
Ryanodine-sensitive intracellular Ca2+ channels (RyRs) open upon binding Ca2+ at cytosolic-facing sites. This results i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7f7221b55ed2eb415a626d2968e2355
https://doi.org/10.1085/jgp.201711959
https://doi.org/10.1085/jgp.201711959
Autor:
Edward N. Pugh
Publikováno v:
The Journal of General Physiology
A retrospective on the scientific importance and impact of Hecht, Shlaer, and Pirenne’s classic 1942 paper, “Energy, Quanta, and Vision.”
Vertebrate rod photoreceptors evolved the astonishing ability to respond reliably to single photons.
Vertebrate rod photoreceptors evolved the astonishing ability to respond reliably to single photons.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::623367ec81de67951a9f7193ae68832e
http://europepmc.org/articles/PMC5839725
http://europepmc.org/articles/PMC5839725
Autor:
Francisco Bezanilla
Publikováno v:
The Journal of General Physiology
A voltage change across a membrane protein moves charges or dipoles producing a gating current that is an electrical expression of a conformational change.
Many membrane proteins sense the voltage across the membrane where they are inserted, and
Many membrane proteins sense the voltage across the membrane where they are inserted, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b6732586ab82731861dbaf1eadc1a35
http://europepmc.org/articles/PMC6028497
http://europepmc.org/articles/PMC6028497
Publikováno v:
The Journal of General Physiology
Armstrong and Hollingworth discuss inactivation in the light of modern structural data from K and Na channels.
We are wired with conducting cables called axons that rapidly transmit electrical signals (e.g., “Ouch!”) from, for example, the t
We are wired with conducting cables called axons that rapidly transmit electrical signals (e.g., “Ouch!”) from, for example, the t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34d4fbac695d51c1327e93a7680977f1
https://doi.org/10.1085/jgp.201711835
https://doi.org/10.1085/jgp.201711835
Autor:
Osvaldo Alvarez, Ramon Latorre
Publikováno v:
Journal Of General Physiology
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
The Journal of General Physiology
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
The Journal of General Physiology
Alvarez and Latorre describe the long-lasting contribution of Goldman’s equation to our understanding of membrane transport.
In 1943, David Goldman published a seminal paper in The Journal of General Physiology that reported a concise expressi
In 1943, David Goldman published a seminal paper in The Journal of General Physiology that reported a concise expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0adab707f71061e4648862fd6b671a76
https://doi.org/10.1085/jgp.201711839
https://doi.org/10.1085/jgp.201711839
Autor:
Allan H. Bretag
Publikováno v:
The Journal of General Physiology
Bretag traces the history of glass microelectrodes back to the 17th century.
Soon after the glass micropipette was invented as a micro-tool for manipulation of single bacteria and the microinjection and microsurgery of living cells, it was seen
Soon after the glass micropipette was invented as a micro-tool for manipulation of single bacteria and the microinjection and microsurgery of living cells, it was seen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c894c8cc6462810c83d977edc32f86
https://doi.org/10.1085/jgp.201611634
https://doi.org/10.1085/jgp.201611634