Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Miles W Cloyd"'
Publikováno v:
Journal of Virology. 84:8348-8352
The clinical significance of persistent residual viremia in patients on prolonged highly active antiretroviral therapy (HAART) is not clear. Moreover, it remains to be demonstrated whether residual viremia consists of viruses capable of spreading inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1940d92fc417457b111d5d8560e8c7e5
https://doi.org/10.1128/jvi.00362-10
https://doi.org/10.1128/jvi.00362-10
Autor:
Melissa M. Smith, Miles W. Cloyd, Scott C. Weaver, Gautam K. Sahu, Simon D. W. Frost, David P. Paar
Publikováno v:
Journal of Medical Virology. 81:9-15
The cellular source(s) and the clinical significance of persistent low-level viremia, below 50 HIV RNA copies per ml of plasma, achieved in many patients with high adherence to highly active antiretroviral therapy (HAART) remain unclear. Also, it is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebb698f9913185c4e3f6e2cabcf332a0
https://doi.org/10.1002/jmv.21366
https://doi.org/10.1002/jmv.21366
Publikováno v:
Virology. 355(2):127-137
Studies of mechanisms of HIV-latency and its reactivation in long-lived resting CD4+ T-lymphocytes in patients have been limited due to the very low frequency of these cells ( approximately 1-10 cells per 10(6) CD4+ T-cells). To circumvent this obsta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22784d953378bf14c3b884f0740f9a84
Autor:
Jingzhi Pan, Joyce Poast, Miles W. Cloyd, Stephen K. Tyring, Samuel Baron, Gautam K. Sahu, Jianmin Chen, Hung Lee
Publikováno v:
Antiviral Research. 70:21-27
Very early detection of HIV infection could help decrease the spread of HIV, improve safety of the blood supply, and permit earlier treatment. Early detection was reported when native gp41 antigen was used to detect antibodies that occurred 2-6 weeks
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5107b5a7abcf266b5a3bbf389f1ac46c
https://doi.org/10.1016/j.antiviral.2005.12.008
https://doi.org/10.1016/j.antiviral.2005.12.008
Publikováno v:
International Immunology. 17:729-736
In HIV-infected patients, increased levels of IL-10, mainly produced by virally infected monocytes, were reported to be associated with impaired cell-mediated immune responses. In this study, we investigated how HIV-1 induces IL-10 production in huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cf93316f401c86820e8b4553ed252cb
https://doi.org/10.1093/intimm/dxh252
https://doi.org/10.1093/intimm/dxh252
Autor:
Miles W. Cloyd, E. G. Briscoe, Jenny J.-Y. Chen, Mark E. Shirtliff, Jason C. Huang, S. A. Ali, Fernando Cesani, David P. Paar
Publikováno v:
Journal of Leukocyte Biology. 72:271-278
The mechanism(s) by which human immunodeficiency virus (HIV) causes depletion of CD4 lymphocytes remains unknown. Evidence has been reported for a mechanism involving HIV binding to (and signaling) resting CD4 lymphocytes in lymphoid tissues, resulti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efdc7c2f13f4309192f4d650f3304094
https://doi.org/10.1189/jlb.72.2.271
https://doi.org/10.1189/jlb.72.2.271
Autor:
Gautam K. Sahu, Liqiang Wang, David P. Paar, Jianmin Chen, John R. Petersen, Keith M. Ramsey, Miles W. Cloyd, Stephen K. Tyring, Alexander J. Indrikovs, Jenny J.-Y. Chen
Publikováno v:
The Journal of Infectious Diseases. 186:321-331
On the basis of human immunodeficiency virus (HIV) needlestick studies, the time to seroconversion for anti-HIV antibodies is 1-9 months (mean, approximately 2-3 months). However, an earlier marker of an immune response to HIV often occurs-serum anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a542777f2edfcd40c4918816673d16a
https://doi.org/10.1086/341661
https://doi.org/10.1086/341661
Publikováno v:
Current Molecular Medicine. 1:545-550
HIV infection causes an acquired immunodeficiency, principally because of depletion of CD4 lymphocytes. The mechanism by which the virus depletes these cells, however, is not clearly understood. Since the virus predominantly infects CD4 lymphocytes i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1a255532d8f4c19dcf86223626dd882
https://doi.org/10.2174/1566524013363320
https://doi.org/10.2174/1566524013363320
Publikováno v:
The Journal of Infectious Diseases. 181:498-504
Salivary transmission by the 30 million human immunodeficiency virus (HIV) carriers is rare, despite kissing, aerosolization, and dental treatment. The main protective mechanism of saliva is reported to be inactivation of HIV-transmitting leukocytes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1811888736d087d6f386d156997f902
https://doi.org/10.1086/315251
https://doi.org/10.1086/315251
Publikováno v:
The Journal of Immunology. 162:268-276
Recently, we reported that abortive HIV infection of resting human T lymphocytes up-regulated expression of CD62L, the receptor for homing to lymph nodes (LNs), and enhanced homing of these cells from the blood into the LNs (Wang et al., 1997, Virolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d39e4959b0e4c021429369e7fe980dac
https://doi.org/10.4049/jimmunol.162.1.268
https://doi.org/10.4049/jimmunol.162.1.268