Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Miles Trupp"'
Publikováno v:
Particle and Fibre Toxicology, Vol 19, Iss 1, Pp 1-12 (2022)
Abstract While it is known that air borne ultrafine particulate matter (PM) may pass through the pulmonary circulation of blood at the alveolar level between lung and heart and cross the air-blood barrier, the mechanism and effects are not completely
Externí odkaz:
https://doaj.org/article/c44edb95a90d4e8dbc1258d69e331b41
Autor:
William J. Griffiths, Jonas Abdel-Khalik, Sarah F. Moore, Ruwani S. Wijeyekoon, Peter J. Crick, Eylan Yutuc, Krista Farrell, David P. Breen, Caroline H. Williams-Gray, Spyridon Theofilopoulos, Ernest Arenas, Miles Trupp, Roger A. Barker, Yuqin Wang
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Disordered cholesterol metabolism is linked to neurodegeneration. In this study we investigated the profile of cholesterol metabolites found in the cerebrospinal fluid (CSF) of Parkinson’s disease (PD) patients. When adjustments were made for confo
Externí odkaz:
https://doaj.org/article/abaae19036454c66a3664ff79c96a45e
Autor:
Rima Kaddurah-Daouk, Rebecca A. Baillie, Hongjie Zhu, Zhao-Bang Zeng, Michelle M. Wiest, Uyen Thao Nguyen, Katie Wojnoonski, Steven M. Watkins, Miles Trupp, Ronald M. Krauss
Publikováno v:
PLoS ONE, Vol 8, Iss 5 (2013)
Externí odkaz:
https://doaj.org/article/a95c407dd9d64353acf6ddc958b6b283
Autor:
Miles Trupp, Hongjie Zhu, William R Wikoff, Rebecca A Baillie, Zhao-Bang Zeng, Peter D Karp, Oliver Fiehn, Ronald M Krauss, Rima Kaddurah-Daouk
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e38386 (2012)
Statins are widely prescribed for reducing LDL-cholesterol (C) and risk for cardiovascular disease (CVD), but there is considerable variation in therapeutic response. We used a gas chromatography-time-of-flight mass-spectrometry-based metabolomics pl
Externí odkaz:
https://doaj.org/article/7e9ff2a16e33412c8b31b63447616a9f
Autor:
Rima Kaddurah-Daouk, Rebecca A Baillie, Hongjie Zhu, Zhao-Bang Zeng, Michelle M Wiest, Uyen Thao Nguyen, Katie Wojnoonski, Steven M Watkins, Miles Trupp, Ronald M Krauss
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e25482 (2011)
Although statins are widely prescribed medications, there remains considerable variability in therapeutic response. Genetics can explain only part of this variability. Metabolomics is a global biochemical approach that provides powerful tools for map
Externí odkaz:
https://doaj.org/article/158850f23f9c42c4aecd23114443f7cd
While it is known that air borne particulate matter (PM2.5) may pass through the pulmonary circulation of blood at the alveolar level between lung and heart and cross the air-blood barrier, the mechanism and effects are not completely clear. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6226f58976b5686820e148bee06105e1
https://doi.org/10.21203/rs.3.rs-1503565/v1
https://doi.org/10.21203/rs.3.rs-1503565/v1
Autor:
David Bäckström, Gabriel Granåsen, Susanna Jakobson Mo, Katrine Riklund, Miles Trupp, Henrik Zetterberg, Kaj Blennow, Lars Forsgren, Magdalena Eriksson Domellöf
The progression of cognitive decline is heterogeneous in the three most common idiopathic parkinsonian diseases: Parkinson disease, multiple system atrophy and progressive supranuclear palsy. The causes for this heterogeneity are not fully understood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d88ab970cfa9dc9a4d94919e79cfc92c
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-196241
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-196241
Autor:
Miles Trupp, Lars Forsgren, Anders Öhman, Anna Wuolikainen, Peter M. Andersen, Junfang Wu, Gunnar Wingsle, Shaochun Zhu, Thomas Moritz
Publikováno v:
Journal of Molecular Neuroscience
The neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and Parkinson’s disease (PD) share some common molecular deficits including disruption of protein homeostasis leading to disease-specific protein aggregation. While insoluble protei
Autor:
Peter E. Clayton, Miles Trupp, Anders Öhman, Youssef Khalil, Buket Dalgic, Paul R.S. Baker, William J. Griffiths, Yuqin Wang, Manuela Pacciarini, Silvia Vilarinho, Sinan Sari, Lars Forsgren, Alison Dickson, Eylan Yutuc, Ludger Schöls, Philip Höflinger, Lisa Connell, Lauren Griffiths
Publikováno v:
Analytica Chimica Acta
Analytica chimica acta 1154, 338259-(2021). doi:10.1016/j.aca.2021.338259
Analytica chimica acta 1154, 338259-(2021). doi:10.1016/j.aca.2021.338259
Both plasma and cerebrospinal fluid (CSF) are rich in cholesterol and its metabolites. Here we describe in detail a methodology for the identification and quantification of multiple sterols including oxysterols and sterol-acids found in these fluids.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b05c1e9077836fb6b8692fbf73b5dbb
https://avesis.gazi.edu.tr/publication/details/9a0486fb-2afc-4a87-9560-7f976912332c/oai
https://avesis.gazi.edu.tr/publication/details/9a0486fb-2afc-4a87-9560-7f976912332c/oai
Autor:
Thomas Moritz, Henrik Antti, Peter M. Andersen, Miles Trupp, Pär Jonsson, Stefan L. Marklund, Lars Forsgren, Anna Wuolikainen, Maria Ahnlund
Publikováno v:
Molecular BioSystems. 12:1287-1298
Amyotrophic lateral sclerosis (ALS) and Parkinson's disease (PD) are protein-aggregation diseases that lack clear molecular etiologies. Biomarkers could aid in diagnosis, prognosis, planning of care, drug target identification and stratification of p