Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Miles Hacker"'
Publikováno v:
Clinical Neuropharmacology. 39:102-111
OBJECTIVE This study aimed to present anthracenedione agents that have been used to treat multiple sclerosis (MS), problems related to their use, and knowledge gained from our experiences using these agents to develop more efficacious drugs with fewe
Autor:
William T. Gunning, Boyd M. Koffman, Anthony Quinn, Alex J. Kiraly, Sarah Rasche, Miles Hacker
Publikováno v:
Clinical Immunology. 141:304-316
Mitoxantrone is one of the few FDA-approved drugs available to treat rapidly progressing forms of multiple sclerosis; however, its utilization is compromised by a cardiotoxic potential and the risk of mitoxantrone-induced leukemia. BBR3378, a novel a
Autor:
Kenneth Alexander, Kenneth Bachmann, James Bigelow, William Bress, James P. Byers, Edward Calabrese, Jen-Fu Chiu, Paul Erhardt, Aaron Grabovich, Martin Holcik, Miles Hacker, Lori Hazlehurst, Qing-Yu He, Terry Kenakin, Eric C. LaCasse, John S. Lazo, Markos Leggas, Karen Lounsberry, Patrick J. McNamara, Georgi V. Petkov, George S. Robertson, Jeffrey G. Sarver, David R. Taft, Pei Tang, William R. Taylor, Tommy S. Tillman, Ying Wang, Yan Xu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ad8a8a9483d33517e712850ee5cea52
https://doi.org/10.1016/b978-0-12-369521-5.00024-5
https://doi.org/10.1016/b978-0-12-369521-5.00024-5
Autor:
Miles Hacker
Publisher Summary This chapter discusses various types of adverse drug reactions (ADRs) using specific examples to demonstrate the types of ADRs that can be encountered when drugs are administered as well as factors that may impact the incidence or s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29ab69e7686eb0a5230d459d7ab7d743
https://doi.org/10.1016/b978-0-12-369521-5.00013-0
https://doi.org/10.1016/b978-0-12-369521-5.00013-0
Autor:
Miles Hacker
Publisher Summary This chapter discusses the progression of pharmacology from the science of testing crude extracts of plants, animals, and minerals for their medicinal properties, to the science it is today, in which isolated chemicals are examined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07ea1fae9f535d9416087800d766648e
https://doi.org/10.1016/b978-0-12-369521-5.00001-4
https://doi.org/10.1016/b978-0-12-369521-5.00001-4
Pharmacology meets the rapidly emerging needs of programs training pharmacologic scientists seeking careers in basic research and drug discovery rather than such applied fields as pharmacy and medicine. While the market is crowded with many clinical
Publikováno v:
JNCI: Journal of the National Cancer Institute.
Inasmuch as solid tumor growth and some intervention methods for tumor control have often been related to the low oxygen levels in tumor tissue, and a special role for hypoxia, perhaps even in oncogenesis, has been suggested by observations of unexpe