Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Miles H Linde"'
Autor:
Miles H. Linde, Amy C. Fan, Thomas Köhnke, Aaron C. Trotman-Grant, Sarah F. Gurev, Paul Phan, Feifei Zhao, Naomi L. Haddock, Kevin A. Nuno, Eric J. Gars, Melissa Stafford, Payton L. Marshall, Christopher G. Dove, Ian L. Linde, Niklas Landberg, Lindsay P. Miller, Robbie G. Majzner, Tian Yi Zhang, Ravindra Majeti
Publikováno v:
Cancer Discovery. 13:1164-1185
Therapeutic cancer vaccination seeks to elicit activation of tumor-reactive T cells capable of recognizing tumor-associated antigens (TAA) and eradicating malignant cells. Here, we present a cancer vaccination approach utilizing myeloid-lineage repro
Autor:
June Ho Shin, Uriel Y. Moreno-Nieves, Luhua H. Zhang, Chen Chen, Amera L. Dixon, Miles H. Linde, Emily M. Mace, John B. Sunwoo
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Natural killer (NK) cells are effector cells of the innate immune system involved in defense against virus-infected and transformed cells. The effector function of NK cells is linked to their ability to migrate to sites of inflammation or damage. The
Externí odkaz:
https://doaj.org/article/1050bd20455f4979aa2639d0ae1c8b72
Autor:
Nathaniel W. Mabe, Min Huang, Guillermo N. Dalton, Gabriela Alexe, Daniel A. Schaefer, Anna C. Geraghty, Amanda L. Robichaud, Amy S. Conway, Delan Khalid, Marius M. Mader, Julia A. Belk, Kenneth N. Ross, Michal Sheffer, Miles H. Linde, Nghi Ly, Winnie Yao, Maria Caterina Rotiroti, Benjamin A. H. Smith, Marius Wernig, Carolyn R. Bertozzi, Michelle Monje, Constantine S. Mitsiades, Ravindra Majeti, Ansuman T. Satpathy, Kimberly Stegmaier, Robbie G. Majzner
Publikováno v:
Nature Cancer. 3:976-993
Immunotherapy with anti-GD2 antibodies has advanced the treatment of children with high-risk neuroblastoma, but nearly half of patients relapse, and little is known about mechanisms of resistance to anti-GD2 therapy. Here, we show that reduced GD2 ex
Autor:
Ravindra Majeti, Tian Yi Zhang, Robbie G. Majzner, Lindsay P. Miller, Niklas Landberg, Ian L. Linde, Christopher G. Dove, Payton L. Marshall, Melissa Stafford, Eric J. Gars, Kevin A. Nuno, Naomi L. Haddock, Feifei Zhao, Paul Phan, Sarah F. Gurev, Aaron C. Trotman-Grant, Thomas Köhnke, Amy C. Fan, Miles H. Linde
Primary B-ALL TR-APCs can be generated via exogenous cytokine stimulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ac3a0c5c5fd89e0d40657f493952de5
https://doi.org/10.1158/2159-8290.22758813.v1
https://doi.org/10.1158/2159-8290.22758813.v1
Autor:
Ravindra Majeti, Tian Yi Zhang, Robbie G. Majzner, Lindsay P. Miller, Niklas Landberg, Ian L. Linde, Christopher G. Dove, Payton L. Marshall, Melissa Stafford, Eric J. Gars, Kevin A. Nuno, Naomi L. Haddock, Feifei Zhao, Paul Phan, Sarah F. Gurev, Aaron C. Trotman-Grant, Thomas Köhnke, Amy C. Fan, Miles H. Linde
Therapeutic cancer vaccination seeks to elicit activation of tumor-reactive T cells capable of recognizing tumor-associated antigens (TAA) and eradicating malignant cells. Here, we present a cancer vaccination approach utilizing myeloid-lineage repro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14b925c26948e5a4cde02ebc0fbbb822
https://doi.org/10.1158/2159-8290.c.6615886.v2
https://doi.org/10.1158/2159-8290.c.6615886.v2
Autor:
Ravindra Majeti, Tian Yi Zhang, Robbie G. Majzner, Lindsay P. Miller, Niklas Landberg, Ian L. Linde, Christopher G. Dove, Payton L. Marshall, Melissa Stafford, Eric J. Gars, Kevin A. Nuno, Naomi L. Haddock, Feifei Zhao, Paul Phan, Sarah F. Gurev, Aaron C. Trotman-Grant, Thomas Köhnke, Amy C. Fan, Miles H. Linde
Summary of clinical features of primary B-ALL specimens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::630e8f2118b951a8d89b9a985b46d580
https://doi.org/10.1158/2159-8290.22758810.v1
https://doi.org/10.1158/2159-8290.22758810.v1
Autor:
Crystal L. Mackall, John M. Maris, Poul H.B. Sorensen, Michelle Monje, Ravindra Majeti, Martha M. Quezado, Siddhartha S. Mitra, Ezio Bonvini, Alla Sekunova, Alberto Delaidelli, Brad St Croix, Zhongyu Zhu, Dimiter S. Dimitrov, Rimas J. Orentas, Daniel W. Lee, Louai Labanieh, Elena Sotillo, Christopher Rota, Peng Xu, Miles H. Linde, Skyler P. Rietberg, Christopher W. Mount, Yongzhi Cui, Sabine Heitzeneder, Anandani Nellan, Johanna L. Theruvath, Robbie G. Majzner
Supplementary Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57539fa5ed0cb1c256eb26d2382cbc0b
https://doi.org/10.1158/1078-0432.22472025.v1
https://doi.org/10.1158/1078-0432.22472025.v1
Autor:
Crystal L. Mackall, John M. Maris, Poul H.B. Sorensen, Michelle Monje, Ravindra Majeti, Martha M. Quezado, Siddhartha S. Mitra, Ezio Bonvini, Alla Sekunova, Alberto Delaidelli, Brad St Croix, Zhongyu Zhu, Dimiter S. Dimitrov, Rimas J. Orentas, Daniel W. Lee, Louai Labanieh, Elena Sotillo, Christopher Rota, Peng Xu, Miles H. Linde, Skyler P. Rietberg, Christopher W. Mount, Yongzhi Cui, Sabine Heitzeneder, Anandani Nellan, Johanna L. Theruvath, Robbie G. Majzner
Purpose:Patients with relapsed pediatric solid tumors and CNS malignancies have few therapeutic options and frequently die of their disease. Chimeric antigen receptor (CAR) T cells have shown tremendous success in treating relapsed pediatric acute ly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e4c51cc5835ce4d4215a2aaf914bc4b
https://doi.org/10.1158/1078-0432.c.6528090
https://doi.org/10.1158/1078-0432.c.6528090
Autor:
Joy Q He, Amira Latif-Hernandez, Makoto Suematsu, Miles H. Linde, Esha Gauba, Ling Liu, Ravi Majeti, Katrin I. Andreasson, Peter K. Moon, Yuki Sugiura, Joshua D. Rabinowitz, Irving L. Weissman, Amit Joshi, Aarooran Sivakumaran Durairaj, Amanda J. Rubin, Melanie R. McReynolds, Qian Wang, Paras S. Minhas, Daria Mochly-Rosen, Congcong Wang, Frank M. Longo
Publikováno v:
Nature. 590:122-128
Ageing is characterized by the development of persistent pro-inflammatory responses that contribute to atherosclerosis, metabolic syndrome, cancer and frailty1-3. The ageing brain is also vulnerable to inflammation, as demonstrated by the high preval
Autor:
Anupama Narla, Melissa Stafford, Ravindra Majeti, Raymond Yin, Eric Gars, Daniel Thomas, Tian Y. Zhang, Yusuke Nakauchi, Satinder Kaur, Armon Azizi, Ritika Dutta, Thomas Köhnke, Miles H. Linde
Publikováno v:
J Clin Invest
Cancer-related anemia is present in more than 60% of newly diagnosed cancer patients and is associated with substantial morbidity and high medical costs. Drugs that enhance erythropoiesis are urgently required to decrease transfusion rates and improv