Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Miles Fuller"'
Publikováno v:
Genomics Data, Vol 9, Iss C, Pp 10-17 (2016)
Emerging evidence suggests molecular chaperones have a role in the pathogenesis of obesity and diabetes. As αB-crystallin and HspB2 are molecular chaperones and data suggests their expression is elevated in the skeletal muscle of diabetic and obese
Externí odkaz:
https://doaj.org/article/2a4cbeb0754c41c28803c681c40a9079
Publikováno v:
Emerging Themes in Epidemiology, Vol 13, Iss 1, Pp 1-9 (2016)
Abstract The obesity epidemic has emerged over the past few decades and is thought to be a result of both genetic and environmental factors. A newly identified factor, the gut microbiota, which is a bacterial ecosystem residing within the gastrointes
Externí odkaz:
https://doaj.org/article/52bdfcd3e13743ba8f7f2eae845fbefc
Autor:
Miles Fuller, Xiaoran Li, Robert Fisch, Moneb Bughara, Barton Wicksteed, Petia Kovatcheva-Datchary, Brian T Layden
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167837 (2016)
During the insulin resistant phase of pregnancy, the mRNA expression of free fatty acid 2 receptor (Ffar2) is upregulated and as we recently reported, this receptor contributes to insulin secretion and pancreatic beta cell mass expansion in order to
Externí odkaz:
https://doaj.org/article/95d8ecb6db144fe2a6584f5b706cafbe
Autor:
Jack A. Gilbert, Medha Priyadarshini, Fredrik Bäckhed, Miles Fuller, Michael R. Brodsky, William L. Lowe, Sean M. Gibbons, Petia Kovatcheva-Datchary, M. Geoffrey Hayes, Anthony R. Angueira, Brian T. Layden
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 309:E840-E851
The structure of the human gastrointestinal microbiota can change during pregnancy, which may influence gestational metabolism; however, a mechanism of action remains unclear. Here we observed that in wild-type (WT) mice the relative abundance of Act
Autor:
Hamid R. Hoveyda, Carey Ann Gallini Comeau, Sydney Lavoie, Miles Fuller, Jonathan N. Glickman, Graeme L. Fraser, Monia Michaud, Brian T. Layden, Wendy S. Garrett, Diogo Fonseca-Pereira, Eunyoung Chun, Sena Bae
Publikováno v:
Immunity. 51:871-884.e6
Group 3 innate lymphoid cells (ILC3s) sense environmental signals that are critical for gut homeostasis and host defense. However, the metabolite-sensing G-protein-coupled receptors that regulate colonic ILC3s remain poorly understood. We found that
Autor:
Raghavendra G. Mirmira, Medha Priyadarshini, Charles R. Mackay, Thierry Alquier, Annette Gilchrist, Helena Mancebo, Barton Wicksteed, Vincent Poitout, Miles Fuller, Stephanie R. Villa, Brian T. Layden
Publikováno v:
Molecular Endocrinology. 29:1055-1066
G protein-coupled receptors have been well described to contribute to the regulation of glucose-stimulated insulin secretion (GSIS). The short-chain fatty acid-sensing G protein-coupled receptor, free fatty acid receptor 2 (FFAR2), is expressed in pa
Autor:
Medha Priyadarshini, Anthony R. Angueira, Maureen Gannon, Sarah A. Tersey, Miles Fuller, Bethany A. Carboneau, Tanya Bhardwaj, Annette Gilchrist, Raghavendra G. Mirmira, Rockann E. Mosser, Brian T. Layden, Michael R. Brodsky, Stephanie R. Villa, Helena Mancebo
Publikováno v:
Scientific Reports
The regulation of pancreatic β cell mass is a critical factor to help maintain normoglycemia during insulin resistance. Nutrient-sensing G protein-coupled receptors (GPCR) contribute to aspects of β cell function, including regulation of β cell ma
Autor:
Barton Wicksteed, Xiaoran Li, Robert Fisch, Brian T. Layden, Petia Kovatcheva-Datchary, Miles Fuller, Moneb Bughara
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 12, p e0167837 (2016)
PLoS ONE, Vol 11, Iss 12, p e0167837 (2016)
During the insulin resistant phase of pregnancy, the mRNA expression of free fatty acid 2 receptor (Ffar2) is upregulated and as we recently reported, this receptor contributes to insulin secretion and pancreatic beta cell mass expansion in order to
Publikováno v:
Emerging themes in epidemiology, vol 13, iss 1
Emerging Themes in Epidemiology
Emerging Themes in Epidemiology, Vol 13, Iss 1, Pp 1-9 (2016)
Emerging Themes in Epidemiology
Emerging Themes in Epidemiology, Vol 13, Iss 1, Pp 1-9 (2016)
The obesity epidemic has emerged over the past few decades and is thought to be a result of both genetic and environmental factors. A newly identified factor, the gut microbiota, which is a bacterial ecosystem residing within the gastrointestinal tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5cc592cf0cf95eaa7205d8b9d1b8d18
https://escholarship.org/uc/item/2vx9k9rn
https://escholarship.org/uc/item/2vx9k9rn
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer. 1806:108-121
Investigations over the last decade have established the essential role of growth factors and their receptors during angiogenesis and carcinogenesis. The vascular endothelial growth factor receptor (VEGFR) family in mammals contains three members, VE