Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Miles C Miller"'
Autor:
Sonia Podvin, Ana-Maria Gonzalez, Miles C Miller, Xitong Dang, Hannah Botfield, John E Donahue, Arwa Kurabi, Matthew Boissaud-Cooke, Ryan Rossi, Wendy E Leadbeater, Conrad E Johanson, Raul Coimbra, Edward G Stopa, Brian P Eliceiri, Andrew Baird
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24609 (2011)
By virtue of its ability to regulate the composition of cerebrospinal fluid (CSF), the choroid plexus (CP) is ideally suited to instigate a rapid response to traumatic brain injury (TBI) by producing growth regulatory proteins. For example, Esophagea
Externí odkaz:
https://doaj.org/article/d52375a279d04f549262994acb27c486
Autor:
Lara Cheslow, E. John Wherry, Molly E. Church, Richa Kapoor, M Andres Blanco, Jorge I. Alvarez, Miles C Miller, James Gesualdi, Mohamed S. Abdel-Hakeem, Naïl Benallegue, Alexis M. Crockett, Hania Kebir, Cen Li
Publikováno v:
Brain
The concerted actions of the CNS and the immune system are essential to coordinating the outcome of neuroinflammatory responses. Yet, the precise mechanisms involved in this crosstalk and their contribution to the pathophysiology of neuroinflammatory
Autor:
Molly E. Church, Charles H. Vite, Edward G. Stopa, Melissa D. Sánchez, Gary P. Swain, Guadalupe Ceja, Megan McGeehan, Charles-Antoine Assenmacher, Amit Bar-Or, Priscilla Farias, Jorge I. Alvarez, Miles C Miller
Publikováno v:
J Immunol
Multiple sclerosis (MS) is an idiopathic demyelinating disease in which meningeal inflammation correlates with accelerated disease progression. The study of meningeal inflammation in MS has been limited because of constrained access to MS brain/spina
Autor:
Alexei A. Podtelezhnikov, Conrad E. Johanson, Luiz M Camargo, Andrew Baird, John E. Donahue, David J. Stone, Gerald D. Silverberg, Eva M. Finney, Brian P. Eliceiri, Miles C. Miller, Lisan Parker, Elena Nikonova, Edward G. Stopa, Tara Torabi, Keith Q. Tanis, Ajay Verma
Publikováno v:
Fluids and Barriers of the CNS, Vol 15, Iss 1, Pp 1-10 (2018)
Fluids and Barriers of the CNS
Fluids and Barriers of the CNS
Background In Alzheimer’s disease, there are striking changes in CSF composition that relate to altered choroid plexus (CP) function. Studying CP tissue gene expression at the blood–cerebrospinal fluid barrier could provide further insight into t
Publikováno v:
Neurobiology of Aging. 57:178-185
Decreased clearance of potentially toxic metabolites, due to aging changes, likely plays a significant role in the accumulation of amyloid-beta (Aβ) peptides and other macromolecules in the brain of the elderly and in the patients with Alzheimer's d
Autor:
Miles C. Miller, Boram Kim, Ray H. Chen, Aparna Patra, Suzanne M. de la Monte, Barbara S. Stonestreet, Yow-Pin Lim, Virginia Hovanesian, Edward G. Stopa, Xiaodi Chen, Mehmet Halit Pinar
Publikováno v:
J Neurosci Res
Inter-alpha Inhibitor proteins (IAIPs) are naturally occurring immunomodulatory molecules found in most tissues. We have reported ontogenic changes in the expression of IAIPs in brain during development in sheep and abundant expression of IAIPs in fe
Autor:
Gerald D. Silverberg, Miles C. Miller, Conrad E. Johanson, Doreen P. Osgood, David Freestone, Russell M. Church, Arthur Messier, Jason T. Machan, Catharine Chiu
Publikováno v:
Behavioral Neuroscience. 128:523-536
The goals of this research were to describe age-related changes in brain biochemistry and behavior, and the relationships between them. The chronological ages of greatest change are particularly important for targeting interventions. In this experime
Autor:
Sonia, Podvin, Miles C, Miller, Ryan, Rossi, Jasmine, Chukwueke, John E, Donahue, Conrad E, Johanson, Andrew, Baird, Edward G, Stopa
Publikováno v:
JSM Alzheimer's disease and related dementia. 3(1)
Expression of the orphan C2orf40 gene is associated with the aggregation of the neurofibrillary tangle-protein tau in transgenic mice, tumor suppression, the induction of senescence in CNS, and the activation of microglia and peripheral mononuclear l
Autor:
E. E. Eklund, Miles C. Miller, John E. Donahue, Edward G. Stopa, N. L. Heath, Geralyn Lambert-Messerlian
Publikováno v:
Journal of Neuroendocrinology. 24:962-972
The inhibin/activin family of proteins is known to have a broad distribution of synthesis and expression in many species, as well as a variety of functions in reproductive and other physiological systems. Yet, our knowledge regarding the production a
Autor:
Robert W. Burgess, Miles C. Miller, Kathy Huen, Hira Chaudry, Melissa Lau, Conrad E. Johanson, Steven M. Rauch, Edward G. Stopa, Joshua R. Sanes
Publikováno v:
Journal of Neuropathology & Experimental Neurology. 70:1124-1137
Conditions that compromise the blood-brain barrier (BBB) have been increasingly implicated in the pathogenesis of Alzheimer disease (AD). AGRIN is a heparan sulfate proteoglycan found abundantly in basement membranes of the cerebral vasculature, wher