Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Miles C Duncan"'
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171406 (2017)
Infection of human cells with Yersinia pseudotuberculosis expressing a functional type III secretion system (T3SS) leads to activation of host NF-κB. We show that the Yersinia T3SS activates distinct NF-κB pathways dependent upon bacterial subcellu
Externí odkaz:
https://doaj.org/article/989e23cf033a4f0dae2187fc3de56355
Autor:
Miles C. Duncan, John C. Forbes, Y Nguyen, Lauren M. Shull, Rebecca K. Gillette, David W. Lazinski, Afsar Ali, Robert M. Q. Shanks, Daniel E. Kadouri, Andrew Camilli
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Prey bacteria have evolved different strategies to counteract predation but the genetic basis remains unclear. Here, Duncan et al. identify key genes involved in Vibrio cholerae sensitivity to Bdellovibrio bacteriovorus predation, providing new insig
Externí odkaz:
https://doaj.org/article/9dd47cd48290412ab43fa62a59005ef4
Autor:
Miles C. Duncan, Rebecca K. Gillette, Micah A. Maglasang, Elizabeth A. Corn, Albert K. Tai, David W. Lazinski, Robert M. Q. Shanks, Daniel E. Kadouri, Andrew Camilli
Publikováno v:
mBio, Vol 10, Iss 3 (2019)
ABSTRACT Bdellovibrio bacteriovorus is a bacterial predator capable of killing and replicating inside most Gram-negative bacteria, including antibiotic-resistant pathogens. Despite growing interest in this organism as a potential therapeutic, many of
Externí odkaz:
https://doaj.org/article/b8b6d2cbea3546999ddf7be7c9bfba0d
Autor:
Jessica M. Morgan, Miles C. Duncan, Kevin S. Johnson, Andreas Diepold, Hanh Lam, Allison J. Dupzyk, Lexi R. Martin, Weng Ruh Wong, Judith P. Armitage, Roger G. Linington, Victoria Auerbuch
Publikováno v:
mSphere, Vol 2, Iss 1 (2017)
ABSTRACT The type III secretion system (T3SS) is a bacterial virulence factor expressed by dozens of Gram-negative pathogens but largely absent from commensals. The T3SS is an attractive target for antimicrobial agents that may disarm pathogenic bact
Externí odkaz:
https://doaj.org/article/74f6ceb0df4a419da1d4d7f0ac24f76e
Autor:
Lauren M Shull, Daniel E. Kadouri, Andrew Camilli, Afsar Ali, Y Nguyen, Robert M. Q. Shanks, John C. Forbes, Rebecca K. Gillette, Miles C. Duncan, David W. Lazinski
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Nature Communications
Nature Communications
The bacterial predator Bdellovibrio bacteriovorus is evolved to attack and kill other bacteria, including the human intestinal pathogen Vibrio cholerae. Although B. bacteriovorus exhibit a broad prey range, little is known about the genetic determina
Autor:
David W. Lazinski, Elizabeth A. Corn, Miles C. Duncan, Daniel E. Kadouri, Albert K. Tai, Rebecca K. Gillette, Robert M. Q. Shanks, Micah A. Maglasang, Andrew Camilli
Publikováno v:
mBio
mBio, Vol 10, Iss 3, p e01040-19 (2019)
mBio, Vol 10, Iss 3 (2019)
mBio, Vol 10, Iss 3, p e01040-19 (2019)
mBio, Vol 10, Iss 3 (2019)
Bdellovibrio bacteriovorus is a predatory bacterium that can kill a wide range of Gram-negative bacteria, including many human pathogens. Given the global rise of antibiotic resistance and dearth of new antibiotics discovered in the past 30 years, th
Autor:
Jessica M, Morgan, Miles C, Duncan, Kevin S, Johnson, Andreas, Diepold, Hanh, Lam, Allison J, Dupzyk, Lexi R, Martin, Weng Ruh, Wong, Judith P, Armitage, Roger G, Linington, Victoria, Auerbuch
Publikováno v:
mSphere
The bacterial type III secretion system (T3SS) is widely used by both human and animal pathogens to cause disease yet remains incompletely understood. Deciphering how some natural products, such as the microbial metabolite piericidin, inhibit type II
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171406 (2017)
PloS one, vol 12, iss 2
PLoS ONE
PloS one, vol 12, iss 2
PLoS ONE
Infection of human cells with Yersinia pseudotuberculosis expressing a functional type III secretion system (T3SS) leads to activation of host NF-κB. We show that the Yersinia T3SS activates distinct NF-κB pathways dependent upon bacterial subcellu
Autor:
Weng Ruh Wong, Allison J. Dupzyk, Victoria Auerbuch, Roger G. Linington, Walter M. Bray, Miles C. Duncan
Publikováno v:
Antimicrobial Agents and Chemotherapy. 58:1118-1126
The type III secretion system (T3SS) is a bacterial appendage used by dozens of Gram-negative pathogens to subvert host defenses and cause disease, making it an ideal target for pathogen-specific antimicrobials. Here, we report the discovery and init
Publikováno v:
Antimicrobial agents and chemotherapy, vol 56, iss 11
The recent and dramatic rise of antibiotic resistance among bacterial pathogens underlies the fear that standard treatments for infectious disease will soon be largely ineffective. Resistance has evolved against nearly every clinically used antibioti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c356741c9e88e6338fdf9514c0b005c5
https://escholarship.org/uc/item/0r00h55k
https://escholarship.org/uc/item/0r00h55k