Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Miles J. Dixon"'
Publikováno v:
Advances in Biological Regulation. 52:205-213
Autor:
C. Peter Downes, Miles J. Dixon, Jeroen van der Kaay, Alexander Gray, Ian H. Batty, Joan F. Telfer
Publikováno v:
Biochemical Journal. 407:255-266
Activation of class Ia PI3K (phosphoinositide 3-kinase) produces PtdInsP3, a vital intracellular mediator whose degradation generates additional lipid signals. In the present study vanadate analogues that inhibit PTPs (protein tyrosine phosphatases)
IQGAP proteins reveal an atypical phosphoinositide (aPI) binding domain with a pseudo C2 domain fold
Autor:
Martijn Schenning, Daan M. F. van Aalten, Nick R. Leslie, Ian H. Batty, Miles J. Dixon, C. Peter Downes, Lyudmila Nedyalkova, Yufeng Tong, Mark Agacan, Alexander Gray, Hee-Won Park, Wolfram Tempel
Publikováno v:
The Journal of Biological Chemistry
Background: Phosphoinositide 3-kinase lipid signals exert important biological effects through proteins with specific recognition domains. Results: We identify a novel such protein domain in IQGAP proteins and define its crystal structure and phospho
Autor:
Robert Gourlay, Mark Agacan, Ian H. Batty, Nicholas A. Morrice, Alexander Gray, C. Peter Downes, Miles J. Dixon, Nick R. Leslie, François-Michel Boisvert
Publikováno v:
Molecularcellular proteomics : MCP. 10(4)
Class I phosphoinositide 3-kinases exert important cellular effects through their two primary lipid products, phosphatidylinositol 3,4,5-trisphosphate and phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P(2)). As few molecular targets for PtdIns(3,
Autor:
Ian H. Batty, Jeroen van der kaay, Alex Gray, Joan F. Telfer, Miles J. Dixon, C. Peter Downes
Publikováno v:
Biochemical Journal; 2007, Vol. 407 Issue 2, p255-266, 12p