Zobrazeno 1 - 10
of 2 364
pro vyhledávání: '"Miles, W."'
Autor:
Alison K. Barrett, Manisha R. Shingare, Andreas Rechtsteiner, Kelsie M. Rodriguez, Quynh N. Le, Tilini U. Wijeratne, Corbin E. Mitchell, Miles W. Membreno, Seth M. Rubin, Gerd A. Müller
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Histone deacetylases (HDACs) play a crucial role in transcriptional regulation and are implicated in various diseases, including cancer. They are involved in histone tail deacetylation and canonically linked to transcriptional repression. Pr
Externí odkaz:
https://doaj.org/article/7a712aae55e44cccbb9dbbd6c0a5b6e1
Autor:
Joseph Akoi Boré, Joseph W. S. Timothy, Tom Tipton, Ifono Kekoura, Yper Hall, Grace Hood, Stephanie Longet, Kimberly Fornace, Millimono S. Lucien, Sarah Katarina Fehling, Beatrice K. Koivogui, Si’Ana A. Coggins, Eric D. Laing, Christopher C. Broder, N’ Faly Magassouba, Thomas Strecker, Jeremy Rossman, Kader Konde, Miles W. Carroll
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Human Ebola virus (EBOV) outbreaks caused by persistent EBOV infection raises questions on the role of zoonotic spillover in filovirus epidemiology. To characterise filovirus zoonotic exposure, we collected cross-sectional serum samples from
Externí odkaz:
https://doaj.org/article/35c6500c6d7f4be4b990a51854c1a341
Autor:
Helen Ratcliffe, Karen S. Tiley, Stephanie Longet, Claire Tonry, Cathal Roarty, Chris Watson, Gayatri Amirthalingam, Iason Vichos, Ella Morey, Naomi L. Douglas, Spyridoula Marinou, Emma Plested, Parvinder K. Aley, Eva Galiza, Saul N. Faust, Stephen Hughes, Clare Murray, Marion R. Roderick, Fiona Shackley, Sam Oddie, Tim W.R. Lee, David P.J. Turner, Mala Raman, Stephen Owens, Paul J. Turner, Helen Cockerill, Jamie Lopez Bernal, Samreen Ijaz, John Poh, Justin Shute, Ezra Linley, Ray Borrow, Katja Hoschler, Kevin E. Brown, Miles W. Carroll, Paul Klenerman, Susanna J. Dunachie, Mary Ramsay, Merryn Voysey, Thomas Waterfield, Matthew D. Snape
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108500- (2023)
Summary: SARS-CoV-2 infections in children are generally asymptomatic or mild and rarely progress to severe disease and hospitalization. Why this is so remains unclear. Here we explore the potential for protection due to pre-existing cross-reactive s
Externí odkaz:
https://doaj.org/article/d001144b1e95484bbbfeb1677546d166
Autor:
Ratcliffe, Helen, Tiley, Karen S., Longet, Stephanie, Tonry, Claire, Roarty, Cathal, Watson, Chris, Amirthalingam, Gayatri, Vichos, Iason, Morey, Ella, Douglas, Naomi L., Marinou, Spyridoula, Plested, Emma, Aley, Parvinder K., Galiza, Eva, Faust, Saul N., Hughes, Stephen, Murray, Clare, Roderick, Marion R., Shackley, Fiona, Oddie, Sam, Lee, Tim W.R., Turner, David P.J., Raman, Mala, Owens, Stephen, Turner, Paul J., Cockerill, Helen, Lopez Bernal, Jamie, Ijaz, Samreen, Poh, John, Shute, Justin, Linley, Ezra, Borrow, Ray, Hoschler, Katja, Brown, Kevin E., Carroll, Miles W., Klenerman, Paul, Dunachie, Susanna J., Ramsay, Mary, Voysey, Merryn, Waterfield, Thomas, Snape, Matthew D.
Publikováno v:
In iScience 15 December 2023 26(12)
Autor:
Hannah Goldswain, Xiaofeng Dong, Rebekah Penrice-Randal, Muhannad Alruwaili, Ghada T. Shawli, Tessa Prince, Maia Kavanagh Williamson, Jayna Raghwani, Nadine Randle, Benjamin Jones, I’ah Donovan-Banfield, Francisco J. Salguero, Julia A. Tree, Yper Hall, Catherine Hartley, Maximilian Erdmann, James Bazire, Tuksin Jearanaiwitayakul, Malcolm G. Semple, Peter J. M. Openshaw, J. Kenneth Baillie, ISARIC4C Investigators, Stevan R. Emmett, Paul Digard, David A. Matthews, Lance Turtle, Alistair C. Darby, Andrew D. Davidson, Miles W. Carroll, Julian A. Hiscox
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-23 (2023)
Abstract Background The mutational landscape of SARS-CoV-2 varies at the dominant viral genome sequence and minor genomic variant population. During the COVID-19 pandemic, an early substitution in the genome was the D614G change in the spike protein,
Externí odkaz:
https://doaj.org/article/b3d75d58548e46f4b79481a60a9b08d2
Autor:
Stephanie Longet, Cristina Leggio, Joseph Akoi Bore, Stephanie Key, Tom Tipton, Yper Hall, Fara Raymond Koundouno, Hilary Bower, Tapan Bhattacharyya, N’Faly Magassouba, Stephan Günther, Ana-Maria Henao-Restrapo, Jeremy S. Rossman, Mandy Kader Konde, Kimberly Fornace, Miles W. Carroll
Publikováno v:
Emerging Infectious Diseases, Vol 29, Iss 2, Pp 304-313 (2023)
Lassa fever virus (LASV) is the causative agent of Lassa fever, a disease endemic in West Africa. Exploring the relationships between environmental factors and LASV transmission across ecologically diverse regions can provide crucial information for
Externí odkaz:
https://doaj.org/article/45154d73b7f74ba986ea9966f3c980a3
Autor:
Napier, Jarred, Batool, Farwa, Sundararaghavan, Vikram L., Jackson, Miles W., Vely, Aela, Khorfan, Rhami, Hance, LaWaun, Jones, Diane J., Heidenreich, Michael J., Aziz, Abdulhameed
Publikováno v:
In Annals of Vascular Surgery July 2023 93:268-274
Autor:
I’ah Donovan-Banfield, Rebekah Penrice-Randal, Hannah Goldswain, Aleksandra M. Rzeszutek, Jack Pilgrim, Katie Bullock, Geoffrey Saunders, Josh Northey, Xiaofeng Dong, Yan Ryan, Helen Reynolds, Michelle Tetlow, Lauren E. Walker, Richard FitzGerald, Colin Hale, Rebecca Lyon, Christie Woods, Shazaad Ahmad, Dennis Hadjiyiannakis, Jimstan Periselneris, Emma Knox, Calley Middleton, Lara Lavelle-Langham, Victoria Shaw, William Greenhalf, Thomas Edwards, David G. Lalloo, Christopher J. Edwards, Alistair C. Darby, Miles W. Carroll, Gareth Griffiths, Saye H. Khoo, Julian A. Hiscox, Thomas Fletcher
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Molnupiravir is an antiviral that forces lethal error catastrophe in SARS-CoV-2 RNAs. Here, the authors confirm the mechanism of action of molnupiravir in humans using samples obtained from the UK’s AGILE phase IIa clinical trial investigating the
Externí odkaz:
https://doaj.org/article/ce55d33708154cc1b4167b313d922661
Autor:
Bojkova, Denisa, Reus, Philipp, Panosch, Leona, Bechtel, Marco, Rothenburger, Tamara, Kandler, Joshua D., Pfeiffer, Annika, Wagner, Julian U.G., Shumliakivska, Mariana, Dimmeler, Stefanie, Olmer, Ruth, Martin, Ulrich, Vondran, Florian W.R., Toptan, Tuna, Rothweiler, Florian, Zehner, Richard, Rabenau, Holger F., Osman, Karen L., Pullan, Steven T., Carroll, Miles W., Stack, Richard, Ciesek, Sandra, Wass, Mark N., Michaelis, Martin, Cinatl, Jindrich, Jr.
Publikováno v:
In iScience 17 February 2023 26(2)
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