Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Milena Penkowa"'
Publikováno v:
Biomarker Insights, Vol 1, Pp 99-111 (2006)
Metallothionein (MT) is a highly conserved, low-molecular-weight, cysteine-rich protein that occurs in 4 isoforms (MT-I to MT-IV), of which MT-I+II are the major and best characterized proteins. This review will focus on mammalian MT-I+II and their f
Externí odkaz:
https://doaj.org/article/8d418bb3ffb34544948adfb198dc70ca
Autor:
Javier Carrasco, Milena Penkowa, Mercedes Giralt, Jordi Camats, Amalia Molinero, Iain L. Campbell, Richard D. Palmiter, Juan Hidalgo
Publikováno v:
Neurobiology of Disease, Vol 13, Iss 1, Pp 22-36 (2003)
We evaluated the physiological relevance of metallothionein-III (MT-III) in the central nervous system following damage caused by a focal cryolesion onto the cortex by studying Mt3-null mice. In normal mice, dramatic astrogliosis and microgliosis and
Externí odkaz:
https://doaj.org/article/8f9a25f27563409a83d67ccb1338e788
Autor:
Mercedes Giralt, Milena Penkowa, Joaquı́n Hernández, Amalia Molinero, Javier Carrasco, Natalia Lago, Jordi Camats, Iain L. Campbell, Juan Hidalgo
Publikováno v:
Neurobiology of Disease, Vol 9, Iss 3, Pp 319-338 (2002)
Transgenic expression of IL-6 under the control of the GFAP gene promoter (GFAP-IL6 mice) in the CNS causes significant damage and alters the expression of many genes, including the metallothionein (MT) family, especially in the cerebellum. The cross
Externí odkaz:
https://doaj.org/article/7be510ecd7cc4dd0886de28be7c8477e
Autor:
Peter Doering, Meredin Stoltenberg, Milena Penkowa, Jørgen Rungby, Agnete Larsen, Gorm Danscher
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10131 (2010)
Traumatic brain injury (TBI) is one of the leading causes of disability and death among young people. Although much is already known about secondary brain damage the full range of brain tissue responses to TBI remains to be elucidated. A population o
Externí odkaz:
https://doaj.org/article/b8e0e5f23da24e47b4ed785640e7297c
Autor:
Per Boye Hansen, Milena Penkowa
Publikováno v:
Supportive Care in Cancer. 29:533-534
Autor:
Milena Penkowa, Per Boye Hansen
Publikováno v:
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer. 25(4)
High-dose chemotherapy prior to autologous stem cell transplantation (ASCT) leads to adverse effects including mucositis, neutropenia and bacteremia. To reduce the toxicity, we treated myeloma and lymphoma patients with peroral bismuth as an adjuvant
Autor:
Meredin Stoltenberg, Bo Martin Bibby, Jørgen Rungby, Agnete Larsen, Milena Penkowa, Linda J. Locht, Mie Østergaard Pedersen, Sara Markholt
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 109:1-10
Silver is a metal with well-known antibacterial effects. This makes silver an attractive coating material for medical devices for use inside the body, e.g. orthopaedic prostheses and catheters used in neurosurgery as it has been found to reduce the h
Publikováno v:
CNS & Neurological Disorders - Drug Targets. 10:140-145
Neisseria meningitidis (N. meningitidis) causes sepsis, epidemic meningitis, and sometimes also meningoencephalitis. Despite early antibiotic treatment, mortality and morbidity remain significant. We present recent studies on meningococcal disease wi
Publikováno v:
Glia. 58:1220-1227
Neuroglobin (Ngb) is proposed to be a neuron-specific, hypoxia-responsive, neuroprotective protein. However, results are conflicting concerning both Ngb's physiological and pathological significance. This study was designed to investigate the in vivo
Publikováno v:
Pedersen, M Ø, Larsen, A, Stoltenberg, M & Penkowa, M 2010, ' Bio-released gold ions modulate expression of neuroprotective and hematopoietic factors after brain injury ', Brain Research, vol. 1307, pp. 1-13 . https://doi.org/10.1016/j.brainres.2009.10.028
Udgivelsesdato: 2010-Jan-11 The discovery of neural stem cells (NSCs) provides new therapeutic strategies for brain injury by means of endogenous cell renewal. In the injured mouse brain, bio-liberated gold ions from gold implants mediate anti-inflam