Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Milena Mlakić"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7401 (2024)
The targeted compounds in this research, resveratrol analogs 1–14, were synthesized as mixtures of isomers by the Wittig reaction using heterocyclic triphenylphosphonium salts and various benzaldehydes. The planned compounds were those possessing t
Externí odkaz:
https://doaj.org/article/34a4d77e864b4bf9b936f8f2790102c1
Publikováno v:
Biomolecules, Vol 14, Iss 6, p 679 (2024)
New furan, thiophene, and triazole oximes were synthesized through several-step reaction paths to investigate their potential for the development of central nervous systems (CNS)-active and cholinesterase-targeted therapeutics in organophosphorus com
Externí odkaz:
https://doaj.org/article/74cbd348dc0a4a4eb4cc9bf339daea3b
Autor:
Milena Mlakić, Danijela Barić, Ana Ratković, Ivana Šagud, Ivona Čipor, Ivo Piantanida, Ilijana Odak, Irena Škorić
Publikováno v:
Molecules, Vol 29, Iss 7, p 1622 (2024)
Triazoles and triazolium salts are very common subunits in the structures of various drugs. Medicaments with a characteristic 1,2,3-triazole core are also being developed to treat neurodegenerative disorders associated with cholinesterase enzyme acti
Externí odkaz:
https://doaj.org/article/e771056477db42798fb85ba5b4eddc6f
Autor:
Milena Mlakić, Hana Perinić, Vitomir Vušak, Ottó Horváth, Diego Sampedro, Raúl Losantos, Ilijana Odak, Irena Škorić
Publikováno v:
Molecules, Vol 29, Iss 1, p 201 (2023)
Previous biological tests have shown that some resveratrol analogs exhibited significant antioxidative and cholinesterase inhibitory potential, as evidenced by lower IC50 values compared to the established standards, resveratrol and galantamine, resp
Externí odkaz:
https://doaj.org/article/5d459576a69e4fa8871981c2072de62b
Autor:
Milena Mlakić, Ivan Faraho, Ilijana Odak, Borislav Kovačević, Anamarija Raspudić, Ivana Šagud, Martina Bosnar, Irena Škorić, Danijela Barić
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14676 (2023)
New 1,2,3-triazolo(thieno)stilbenes were synthesized as mixtures of isomers and efficiently photochemically transformed to their corresponding substituted thienobenzo/naphtho-triazoles in high isolated yields. The resulting photoproducts were studied
Externí odkaz:
https://doaj.org/article/426e3847138e48e6baa6390e4bbe2a9a
Autor:
Milena Mlakić, Ivona Čipor, Petra Kovačec, Goran Kragol, Ana Ratković, Tatjana Kovačević, Rahela Zadravec, Valentina Milašinović, Krešimir Molčanov, Ivo Piantanida, Irena Škorić
Publikováno v:
Molecules, Vol 28, Iss 11, p 4499 (2023)
A new series of 4H-1,3-benzothiazine dyes were prepared and fully characterized in an aqueous medium. Benzothiazine salts were synthesized either through the classical synthetic pathway using Buchwald–Hartwig amination or through economical and env
Externí odkaz:
https://doaj.org/article/e5cfef5af24e4d14811d3e615a1f1907
Autor:
Milena Mlakić, Ema Đurčević, Ilijana Odak, Danijela Barić, Ines Juričević, Ivana Šagud, Franko Burčul, Zlata Lasić, Željko Marinić, Irena Škorić
Publikováno v:
Molecules, Vol 28, Iss 9, p 3781 (2023)
Naphtho-triazoles and thienobenzo-triazoles have so far proven to be very potent inhibitors of the enzyme butyrylcholinesterase (BChE). Based on these results, in this work, new thienobenzo-thiazoles were designed and synthesized, and their potential
Externí odkaz:
https://doaj.org/article/535a8299ef4a4d399c4ecf303c5a8912
Autor:
Milena Mlakić, Ida Selec, Irena Ćaleta, Ilijana Odak, Danijela Barić, Ana Ratković, Krešimir Molčanov, Irena Škorić
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5879 (2023)
This study aims to test the inhibition potency of new thienobenzo/naphtho-triazoles toward cholinesterases, evaluate their inhibition selectivity, and interpret the obtained results by molecular modeling. The synthesis of 19 new thienobenzo/naphtho-t
Externí odkaz:
https://doaj.org/article/009485afb207410f87b9bfa14ca1e74b
Autor:
Milena Mlakić, Ilijana Odak, Ivan Faraho, Martina Bosnar, Mihailo Banjanac, Zlata Lasić, Željko Marinić, Danijela Barić, Irena Škorić
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 610 (2022)
In this research, the synthesis, photochemistry, and computational study of new cis- and trans-isomers of amino-thienostilbenes is performed to test the efficiency of their production and acid resistance, and to investigate their electronic structure
Externí odkaz:
https://doaj.org/article/ed3addafde30443296e872e45b97d86f
Autor:
Milena Mlakić, Anabela Ljubić, Anita Šalić, Bruno Zelić, Ottó Horváth, Valentina Milašinović, Martin Gojun, Krešimir Molčanov, Irena Škorić
Publikováno v:
Catalysts, Vol 12, Iss 12, p 1510 (2022)
A simple and efficient protocol is utilized for the transformation studies of a thiophene analog of E-resveratrol by photocatalytic oxygenation using an anionic and a cationic free-base porphyrin, as well as their manganese(III) complexes. The starti
Externí odkaz:
https://doaj.org/article/3e7b2ca530d3450da3d014409f19f77a