Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Milena M. V. F. Carvalho"'
Autor:
Margaret H Magdesian, Matthias Gralle, Luiz H Guerreiro, Paulo José I Beltrão, Milena M V F Carvalho, Luís Eduardo da S Santos, Fernando G de Mello, Ricardo A M Reis, Sérgio T Ferreira
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22857 (2011)
The amyloid precursor protein (APP) is well known for giving rise to the amyloid-β peptide and for its role in Alzheimer's disease. Much less is known, however, on the physiological roles of APP in the development and plasticity of the central nervo
Externí odkaz:
https://doaj.org/article/f79b5e71009f43b2a9cfc8411a12416d
Autor:
Fabio A. Mendes, Margaret H. Magdesian, Sergio T. Ferreira, Maria A. Juliano, Leonardo M. Saraiva, Luiz Juliano, José Garcia-Abreu, Milena M. V. F. Carvalho
Publikováno v:
Journal of Biological Chemistry. 283:9359-9368
The amyloid-beta peptide (Abeta) plays a major role in neuronal dysfunction and neurotoxicity in Alzheimer disease. However, the signal transduction mechanisms involved in Abeta-induced neuronal dysfunction remain to be fully elucidated. A major curr