Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Milena Kosic"'
Autor:
Stephane Angers, Kusumika Saha, Jane E. Findlay, Evelyne Lima-Fernandes, Michel Bouvier, Justine S. Paradis, Stefano Marullo, Cédric Auffray, George S. Baillie, Hervé Enslen, Mark G.H. Scott, Alessia Zamborlini, Anne Poupon, Elodie Blondel-Tepaz, Badr Sokrat, Milena Kosic, Louis Gaboury, Marie Leverve
Publikováno v:
Oncogene
Oncogene, Nature Publishing Group, 2021, 40 (12), pp.2243-2257. ⟨10.1038/s41388-021-01704-w⟩
Oncogene, 2021, 40 (12), pp.2243-2257. ⟨10.1038/s41388-021-01704-w⟩
Oncogene, Nature Publishing Group, 2021, 40 (12), pp.2243-2257. ⟨10.1038/s41388-021-01704-w⟩
Oncogene, 2021, 40 (12), pp.2243-2257. ⟨10.1038/s41388-021-01704-w⟩
International audience; Mdm2 antagonizes the tumor suppressor p53. Targeting the Mdm2-p53 interaction represents an attractive approach for the treatment of cancers with functional p53. Investigating mechanisms underlying Mdm2-p53 regulation is there
Autor:
Nishani Rajakulendran, Molaei F, Zachary Steinhart, Stephane Angers, Nicole I. Park, Moloud Ahmadi, Milena Kosic, Gregory T. Macleod, Sichun Lin, Peter B. Dirks, Andy Yang
Glioblastoma stem cells (GSCs) exhibit latent neuronal lineage differentiation potential governed by the proneural transcription factor Achaete-scute homolog 1 (ASCL1) and harnessing and promoting terminal neuronal differentiation has been proposed a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccb456eacdde2c28b0d18c4bd8ae86eb
https://doi.org/10.1101/2021.05.04.442579
https://doi.org/10.1101/2021.05.04.442579
Publikováno v:
Ann Biomed Eng
The development of novel 3D tissue culture systems has enabled the in vitro study of in vivo processes, thereby overcoming many of the limitations of previous 2D tissue culture systems. Advances in biomaterials, including the discovery of novel synth
High-throughput screening in niche-based assay identifies compounds to target preleukemic stem cells
Autor:
Milena Kosic, Anne Marinier, Julianne Ouellette, Elizabeth Ottoni, Diogo F.T. Veiga, Dominique Geoffrion, Philippe P. Roux, Mathieu Tremblay, Bastien Gerby, Paul S. Maddox, Sami Nourreddine, Geneviève Lavoie, Joel Ryan, André Haman, Josée Hébert, Iman Fares, Benjamin H. Kwok, Guy Sauvageau, Trang Hoang, Véronique Litalien, Jana Krosl, Jalila Chagraoui
Publikováno v:
Journal of Clinical Investigation
Journal of Clinical Investigation, American Society for Clinical Investigation, 2016, 126 (12), pp.4569-4584. ⟨10.1172/JCI86489⟩
Journal of Clinical Investigation, American Society for Clinical Investigation, 2016, 126 (12), pp.4569-4584. ⟨10.1172/JCI86489⟩
International audience; Current chemotherapies for T cell acute lymphoblastic leukemia (T-ALL) efficiently reduce tumor mass. Nonetheless, disease relapse attributed to survival of preleukemic stem cells (pre-LSCs) is associated with poor prognosis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cbcccda187174556b63854a00ba6fb3
https://hal.archives-ouvertes.fr/hal-02353313/document
https://hal.archives-ouvertes.fr/hal-02353313/document
Autor:
Dominique Geoffrion, Bastien Gerby, Milena Kosic, Véronique Litalien, Joel Ryan, Anne Marinier, Philippe P. Roux, André Haman, Elizabeth Ottoni, Julianne Ouellette, Benjamin H. Kwok, Jalila Chagraoui, Paul S. Maddox, Geneviève Lavoie, Jana Krosl, Mathieu Tremblay, Guy Sauvageau, Diogo F.T. Veiga, Trang Hoang, Josée Hébert, Iman Fares
Publikováno v:
ResearcherID
Current chemotherapy of pediatric T cell acute lymphoblastic leukemia (T-ALL) efficiently reduces the tumor mass with, however, undesirable long term consequences and remains ineffective in adolescent and adult T-ALL. Furthermore, relapse can be caus