Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Milena Julia Szafraniec"'
Autor:
Małgorzata Szczygieł, Marcin Markiewicz, Milena Julia Szafraniec, Agnieszka Hojda, Leszek Fiedor, Krystyna Urbanska
Publikováno v:
Cancers
Cancers; Volume 14; Issue 2; Pages: 313
Cancers, Vol 14, Iss 313, p 313 (2022)
Cancers; Volume 14; Issue 2; Pages: 313
Cancers, Vol 14, Iss 313, p 313 (2022)
Simple Summary The drug efflux mediated by xenobiotic transporters is one of the best recognized mechanisms of multidrug resistance in cancer that leads to the failure of therapeutic approaches. The aim of our research was to examine the influence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0df581eeccffdf6aa622f711a21a5de4
https://pubmed.ncbi.nlm.nih.gov/35053477
https://pubmed.ncbi.nlm.nih.gov/35053477
Autor:
Milena Julia Szafraniec, Leszek Fiedor
Breast cancer resistance protein (BCRP, ABCG2) is a member of the ATP-binding-cassette (ABC) superfamily of membrane transporters. It is involved in the efflux of a broad range of xenobiotics of highly diverse structures. BCRP activity greatly influe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b9bae9361eb965e45a846dd8fcfdd4b
https://ruj.uj.edu.pl/xmlui/handle/item/285773
https://ruj.uj.edu.pl/xmlui/handle/item/285773
Autor:
Małgorzata Szczygieł, Roxana Zuziak, Milena Julia Szafraniec, Marcin Markiewicz, Krystyna Urbanska, Leszek Fiedor
Publikováno v:
Acta Biochimica Polonica. 64:437-443
All organisms are exposed to numerous stress factors, which include harmful xenobiotics. The diversity of these compounds is enormous, thus in the course of evolution diverse biological defense mechanisms at various levels of organization have develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e3914b13d807425e446a2214920294f
https://doi.org/10.18388/abp.2017_2299
https://doi.org/10.18388/abp.2017_2299
Publikováno v:
Drug metabolism reviews. 46(4)
The xenobiotic transporters are among the most important constituents of detoxification system in living organisms. Breast cancer resistance protein (BCRP/ABCG2) is one of the major transporters involved in the efflux of xenobiotics. To understand it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c628b7c732ccf0a9ad3edb7dd558d9a0
https://pubmed.ncbi.nlm.nih.gov/25036722
https://pubmed.ncbi.nlm.nih.gov/25036722
Autor:
Milena Julia Szafraniec, Małgorzata Szczygieł, Bożena Boroń, Leszek Fiedor, Dariusz Szczygiel, Zenon Matuszak, Krystyna Urbanska, Anna Susz
Efficient application of any therapeutic agent requires the knowledge of the time evolution of drug concentration in tissues. Usually, the collection of such pharmacokinetic data relies on sequential invasive measurements and sacrifice of many animal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f218f68fbf9be40a6a1a922c807f61d
http://ruj.uj.edu.pl/xmlui/handle/item/11834
http://ruj.uj.edu.pl/xmlui/handle/item/11834
Objective: Tacrolimus (FK506) and cyclosporin A (CsA), immunosuppressants widely used in post-transplantional therapy, have been reported to protect neurons in the injured brain. This effect can be exerted directly and indirectly via inflammatory cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23518b56cf72d02bfb2d1f4812e5f308
http://ruj.uj.edu.pl/xmlui/handle/item/31864
http://ruj.uj.edu.pl/xmlui/handle/item/31864