Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Milena Hristova"'
Autor:
David E. Heppner, Christopher M. Dustin, Chenyi Liao, Milena Hristova, Carmen Veith, Andrew C. Little, Bethany A. Ahlers, Sheryl L. White, Bin Deng, Ying-Wai Lam, Jianing Li, Albert van der Vliet
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
The activity of several protein kinases is increased upon cellular production of reactive oxygen species, which can cause cysteine oxidation. Here the authors show that sulfenylation of specific cysteine residues within Src induce local structural ch
Externí odkaz:
https://doaj.org/article/224ec0c26833440495e8da4a22aecfde
Autor:
Caspar Schiffers, Cheryl van de Wetering, Robert A. Bauer, Aida Habibovic, Milena Hristova, Christopher M. Dustin, Sara Lambrichts, Pamela M. Vacek, Emiel F.M. Wouters, Niki L. Reynaert, Albert van der Vliet
Publikováno v:
JCI Insight, Vol 6, Iss 2 (2021)
Chronic obstructive pulmonary disease (COPD) is a chronic respiratory disease characterized by small airway remodeling and alveolar emphysema due to environmental stresses such as cigarette smoking (CS). Oxidative stress is commonly implicated in COP
Externí odkaz:
https://doaj.org/article/ca13401081aa4805b072e1b3e5465641
Autor:
David E. Heppner, Milena Hristova, Tomoaki Ida, Ana Mijuskovic, Christopher M. Dustin, Virág Bogdándi, Jon M. Fukuto, Tobias P. Dick, Péter Nagy, Jianing Li, Takaaki Akaike, Albert van der Vliet
Publikováno v:
Redox Biology, Vol 14, Iss , Pp 379-385 (2018)
The reversible oxidation of protein cysteine residues (Cys-SH) is a key reaction in cellular redox signaling involving initial formation of sulfenic acids (Cys-SOH), which are commonly detected using selective dimedone-based probes. Here, we report t
Externí odkaz:
https://doaj.org/article/898f22d00edd48fb8263a51951fa70c8
Autor:
Tianxin Miao, Andrew C. Little, Alexander Aronshtam, Taylor Marquis, Spencer L. Fenn, Milena Hristova, Dimitry N. Krementsov, Albert van der Vliet, Jeffrey L. Spees, Rachael A. Oldinski
Publikováno v:
Nanomaterials, Vol 10, Iss 4, p 612 (2020)
Innovative cancer treatments, which improve adjuvant therapy and reduce adverse events, are desperately needed. Nanoparticles provide controlled intracellular biomolecule delivery in the absence of activating external cell surface receptors. Prior re
Externí odkaz:
https://doaj.org/article/f6c1e94a56d84c578b00509c501f5603
Autor:
Milena Hristova, Carmen Veith, Aida Habibovic, Ying-Wai Lam, Bin Deng, Miklos Geiszt, Yvonne M.W. Janssen-Heininger, Albert van der Vliet
Publikováno v:
Redox Biology, Vol 2, Iss C, Pp 436-446 (2014)
The NADPH oxidase homolog dual oxidase 1 (DUOX1) plays an important role in innate airway epithelial responses to infection or injury, but the precise molecular mechanisms are incompletely understood and the cellular redox-sensitive targets for DUOX1
Externí odkaz:
https://doaj.org/article/bb6d59741ab349b6869f3d4788daf266
Publikováno v:
Redox Biology, Vol 1, Iss 1, Pp 265-275 (2013)
Cigarette smoking remains a major health concern worldwide, and many of the adverse effects of cigarette smoke (CS) can be attributed to its abundant electrophilic aldehydes, such as acrolein (2-propenal). Previous studies indicate that acrolein read
Externí odkaz:
https://doaj.org/article/142586c60b7b406f82c034df28d3ad1f
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54391 (2013)
The respiratory epithelium is subject to continuous environmental stress and its responses to injury or infection are largely mediated by transactivation of the epidermal growth factor receptor (EGFR) and downstream signaling cascades. Based on previ
Externí odkaz:
https://doaj.org/article/2763b16c5dea40f68fae7e3648c530eb
Akademický článek
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Autor:
Aida Habibovic, Milena Hristova, Carolyn R. Morris, Miao-Chong Joy Lin, Litiele C. Cruz, Jennifer L. Ather, Miklós Geiszt, Vikas Anathy, Yvonne M. W. Janssen-Heininger, Matthew E. Poynter, Anne E. Dixon, Albert van der Vliet
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 324:L228-L242
More than 50% of people with asthma in the United States are obese, and obesity often worsens symptoms of allergic asthma and impairs response to treatment. Based on previously established roles of the epithelial NADPH oxidase DUOX1 in allergic airwa
Akademický článek
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