Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Milena Denkiewicz"'
Autor:
Michal Dmowski, Karolina Makiela-Dzbenska, Malgorzata Jedrychowska, Milena Denkiewicz-Kruk, Iwona J. Fijalkowska
Publikováno v:
Data in Brief, Vol 42, Iss , Pp 108223- (2022)
DNA replication in Saccharomyces cerevisiae and other eukaryotes is performed mainly by polymerase epsilon (Pol ε) on the leading strand and polymerase delta (Pol δ) on the lagging strand. Using a mutant form of a DNA polymerase enables tracking it
Externí odkaz:
https://doaj.org/article/88de81f1b82d4166a1e15732575526bb
Autor:
Malgorzata Jedrychowska, Milena Denkiewicz-Kruk, Malgorzata Alabrudzinska, Adrianna Skoneczna, Piotr Jonczyk, Michal Dmowski, Iwona J Fijalkowska
Publikováno v:
PLoS Genetics, Vol 15, Iss 12, p e1008494 (2019)
Faithful replication and repair of DNA lesions ensure genome maintenance. During replication in eukaryotic cells, DNA is unwound by the CMG helicase complex, which is composed of three major components: the Cdc45 protein, Mcm2-7, and the GINS complex
Externí odkaz:
https://doaj.org/article/4e4502278d9841618e31147cc67f253b
Autor:
Milena Denkiewicz-Kruk, Malgorzata Jedrychowska, Shizuko Endo, Hiroyuki Araki, Piotr Jonczyk, Michal Dmowski, Iwona J. Fijalkowska
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 24, p 9484 (2020)
The CMG complex (Cdc45, Mcm2–7, GINS (Psf1, 2, 3, and Sld5)) is crucial for both DNA replication initiation and fork progression. The CMG helicase interaction with the leading strand DNA polymerase epsilon (Pol ε) is essential for the preferential
Externí odkaz:
https://doaj.org/article/1d51698a3dec486b88aafcd83c7c442d
Autor:
Hiroyuki Araki, Shizuko Endo, Piotr Jonczyk, Milena Denkiewicz-Kruk, Malgorzata Jedrychowska, Michał Dmowski, Iwona J. Fijalkowska
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 9484, p 9484 (2020)
Volume 21
Issue 24
International Journal of Molecular Sciences, Vol 21, Iss 9484, p 9484 (2020)
Volume 21
Issue 24
The CMG complex (Cdc45, Mcm2&ndash
7, GINS (Psf1, 2, 3, and Sld5)) is crucial for both DNA replication initiation and fork progression. The CMG helicase interaction with the leading strand DNA polymerase epsilon (Pol &epsilon
) is essential
7, GINS (Psf1, 2, 3, and Sld5)) is crucial for both DNA replication initiation and fork progression. The CMG helicase interaction with the leading strand DNA polymerase epsilon (Pol &epsilon
) is essential
Autor:
Michal Dmowski, Malgorzata Jedrychowska, Karolina Makiela-Dzbenska, Milena Denkiewicz-Kruk, Sushma Sharma, Andrei Chabes, Hiroyuki Araki, Iwona J. Fijalkowska
Publikováno v:
DNA Repair. 110:103272
DNA replication is performed by replisome proteins, which are highly conserved from yeast to humans. The CMG [Cdc45-Mcm2–7-GINS(Psf1–3, Sld5)] helicase unwinds the double helix to separate the leading and lagging DNA strands, which are replicated
Autor:
Tomasz Koper, Jerzy Ciarkowski, Agnieszka Polit, Anna Sobiecka-Szkatula, Artur Giełdoń, Joanna Skorko-Glonek, Bogdan Banecki, Barbara Lipinska, Adam Lesner, Milena Denkiewicz, Donata Figaj
Publikováno v:
Journal of Biological Chemistry. 289:15880-15893
Bacterial HtrAs are serine proteases engaged in extracytoplasmic protein quality control and are required for the virulence of several pathogenic species. The proteolytic activity of HtrA (DegP) from Escherichia coli, a model prokaryotic HtrA, is sti
Autor:
Iwona J. Fijalkowska, Urszula Wronska, Malgorzata Alabrudzinska, Catherine Suski, Aleksandra Respondek, Milena Denkiewicz, Karolina Makiela-Dzbenska, Piotr Jonczyk, Malgorzata Jaszczur, Ewa Grabowska
Publikováno v:
Molecular Microbiology. 92:659-680
Summary The role of replicative DNA polymerases in ensuring genome stability is intensively studied, but the role of other components of the replisome is still not fully understood. One of such component is the GINS complex (comprising the Psf1, Psf2
Autor:
Donata, Figaj, Artur, Gieldon, Agnieszka, Polit, Anna, Sobiecka-Szkatula, Tomasz, Koper, Milena, Denkiewicz, Bogdan, Banecki, Adam, Lesner, Jerzy, Ciarkowski, Barbara, Lipinska, Joanna, Skorko-Glonek
Publikováno v:
The Journal of biological chemistry. 289(22)
Bacterial HtrAs are serine proteases engaged in extracytoplasmic protein quality control and are required for the virulence of several pathogenic species. The proteolytic activity of HtrA (DegP) from Escherichia coli, a model prokaryotic HtrA, is sti