Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Mildred J Unti"'
Autor:
Richard A. Morgan, Feiyang Ma, Mildred J. Unti, Devin Brown, Paul George Ayoub, Curtis Tam, Lindsay Lathrop, Bamidele Aleshe, Ryo Kurita, Yukio Nakamura, Shantha Senadheera, Ryan L. Wong, Roger P. Hollis, Matteo Pellegrini, Donald B. Kohn
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss , Pp 999-1013 (2020)
Hematopoietic stem cell gene therapy is a promising approach for treating disorders of the hematopoietic system. Identifying combinations of cis-regulatory elements that do not impede packaging or transduction efficiency when included in lentiviral v
Externí odkaz:
https://doaj.org/article/ccffc6e5ef60491090a5500bcef71424
Autor:
Christopher M. Bourne, Leila Peraro, David A. Scheinberg, Megan M. Dacek, Kristen C Vogt, Thomas J. Gardner, Pedro C. Silberman, Manish Malviya, Mildred J Unti, Keifer Kurtz, Renier Brentjens
Publikováno v:
Cancers, Vol 12, Iss 2175, p 2175 (2020)
Cancers
Cancers
The recent emergence of engineered cellular therapies, such as Chimeric antigen receptor (CAR) CAR T and T cell receptor (TCR) engineered T cells, has shown great promise in the treatment of various cancers. These agents aggregate and expand exponent
Autor:
Ryo Kurita, Donald B. Kohn, Matteo Pellegrini, Devin Brown, Shantha Senadheera, Bamidele Aleshe, Curtis Tam, Ryan L. Wong, Roger P. Hollis, Feiyang Ma, Mildred J. Unti, Paul G. Ayoub, Yukio Nakamura, Richard A. Morgan, Lindsay Lathrop
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss, Pp 999-1013 (2020)
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss, Pp 999-1013 (2020)
Hematopoietic stem cell gene therapy is a promising approach for treating disorders of the hematopoietic system. Identifying combinations of cis-regulatory elements that do not impede packaging or transduction efficiency when included in lentiviral v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5023da47317e2dab073d8adb26b5ba3f
https://escholarship.org/uc/item/4sh7x4pq
https://escholarship.org/uc/item/4sh7x4pq
Autor:
Kyle Osborne, Shantha Senadheera, Jason P. Quintos, Devin Brown, Marlene Ruiz, Paul G. Ayoub, Eric Miyahira, Rachel O’Brien, Oliver B. Smith, Bamidele Aleshe, Curtis Tam, Mildred J. Unti, Richard A. Morgan, Colin Koziol, Donald B. Kohn, Roger P. Hollis
Publikováno v:
Mol Ther
Molecular therapy : the journal of the American Society of Gene Therapy, vol 28, iss 1
Molecular therapy : the journal of the American Society of Gene Therapy, vol 28, iss 1
β-globin lentiviral vectors (β-LV) have faced challenges in clinical translation for gene therapy of sickle cell disease (SCD) due to low titer and sub-optimal gene transfer to hematopoietic stem and progenitor cells (HSPCs). To overcome the challe