Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Mildred Felder"'
Autor:
Alexander L. Rakhmilevich, Noah W. Tsarovsky, Mildred Felder, Jen Zaborek, Sritha Moram, Amy K. Erbe, Alexander A. Pieper, Dan V. Spiegelman, Emily M. Cheng, Cole M. Witt, Willem W. Overwijk, Zachary S. Morris, Paul M. Sondel
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundThe majority of experimental approaches for cancer immunotherapy are tested against relatively small tumors in tumor-bearing mice, because in most cases advanced cancers are resistant to the treatments. In this study, we asked if even late-
Externí odkaz:
https://doaj.org/article/29d00bafc93a4a5eba1dd4bd66f05425
Autor:
Noah Tsarovsky, Mildred Felder, Mackenzie Heck, Jacob Slowinski, Kayla Rasmussen, Sabrina VandenHeuvel, Jen Zaborek, Zachary S. Morris, Amy K. Erbe, Paul M. Sondel, Alexander L. Rakhmilevich
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionWe have previously shown that an intratumoral (IT) injection of the hu14.18-IL2 immunocytokine (IC), an anti-GD2 antibody linked to interleukin 2, can serve as an in situ vaccine and synergize with local radiotherapy (RT) to induce T cell
Externí odkaz:
https://doaj.org/article/31fc084eb860409982966059be52b354
Autor:
Paul Sondel, Alexander Rakhmilevich, Anna Hoefges, Mildred Felder, Zachary Morris, Amy Erbe, Arika Feils, Luke Zangl, Ravi Patel, Jacquelyn Hank, Dan Spiegelman, Alexander Pieper, Sritha Moram
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/ba7ea0b6a9b349449d5ef3b343985367
Autor:
Paul Sondel, Alexander Rakhmilevich, Mildred Felder, Zachary Morris, Amy Erbe, Mackenzie Heck, Noah Tsarovsky, Jacob Slowinski, Kayla Rasmussen, Sabrina VandenHeuvel
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/1435c8d8deb44fa4bb6db9f8c7677292
Plumbagin-induced oxidative stress leads to inhibition of Na+/K+-ATPase (NKA) in canine cancer cells
Autor:
Yousef Alharbi, Arvinder Kapur, Mildred Felder, Lisa Barroilhet, Timothy Stein, Bikash R. Pattnaik, Manish S. Patankar
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Abstract The Na+/K+-ATPase (NKA) complex is the master regulator of membrane potential and a target for anti-cancer therapies. Here, we investigate the effect of drug-induced oxidative stress on NKA activity. The natural product, plumbagin increases
Externí odkaz:
https://doaj.org/article/711cb0ad0da842b3aed61841711db73e
Autor:
Arvinder Kapur, Pooja Mehta, Aaron D Simmons, Spencer S. Ericksen, Geeta Mehta, Sean P. Palecek, Mildred Felder, Zach Stenerson, Amruta Nayak, Jose Maria Ayuso Dominguez, Manish Patankar, Lisa M. Barroilhet
Publikováno v:
Cancers, Vol 14, Iss 9, p 2297 (2022)
Oxidative phosphorylation is an active metabolic pathway in cancer. Atovaquone is an oral medication that inhibits oxidative phosphorylation and is FDA-approved for the treatment of malaria. We investigated its potential anti-cancer properties by mea
Externí odkaz:
https://doaj.org/article/e72fa9a2fafb4b76b5a5fa756edeb127
Autor:
Jose M. Ayuso, Regan Truttschel, Max M. Gong, Mouhita Humayun, Maria Virumbrales-Munoz, Ross Vitek, Mildred Felder, Stephen D. Gillies, Paul Sondel, Kari B. Wisinski, Manish Patankar, David J. Beebe, Melissa C. Skala
Publikováno v:
OncoImmunology, Vol 8, Iss 3 (2019)
Immunotherapies against solid tumors face additional challenges compared with hematological cancers. In solid tumors, immune cells and antibodies need to extravasate from vasculature, find the tumor, and migrate through a dense mass of cells. These m
Externí odkaz:
https://doaj.org/article/6a17234ddcc64c4faa63fe3776ab750c
Autor:
Mian M K Shahzad, Mildred Felder, Kai Ludwig, Hannah R Van Galder, Matthew L Anderson, Jong Kim, Mark E Cook, Arvinder K Kapur, Manish S Patankar
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0189524 (2018)
The goal of this study was to investigate the anti-cancer effects of Trans10,cis12 conjugated linoleic acid (t10,c12 CLA). MTT assays and QCM™ chemotaxis 96-wells were used to test the effect of t10,c12 CLA on the proliferation and migration and in
Externí odkaz:
https://doaj.org/article/1393d9ac57394cd1afb5e6e5335b6917
Autor:
Yang Liu, Rebecca J Whelan, Bikash R Pattnaik, Kai Ludwig, Enkateswar Subudhi, Helen Rowland, Nick Claussen, Noah Zucker, Shitanshu Uppal, David M Kushner, Mildred Felder, Manish S Patankar, Arvinder Kapur
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e53178 (2012)
Novel strategies are necessary to improve chemotherapy response in advanced and recurrent endometrial cancer. Here, we demonstrate that terpenoids present in the Steam Distilled Extract of Ginger (SDGE) are potent inhibitors of proliferation of endom
Externí odkaz:
https://doaj.org/article/af28e86b6aa54ab8b87e3ae4a9a1f045
Autor:
Arvinder Kapur, Jose M Ayuso, Shujah Rehman, Santosh Kumari, Mildred Felder, Zach Stenerson, Melisa C Skala, Dave Beebe, Lisa Barroilhet, Manish S Patankar
Publikováno v:
Reproduction. 165:617-628
In brief Developing novel therapies to cure and manage endometriosis is a major unmet need that will benefit over 180 million women worldwide. Results from the current study suggest that inhibitors of oxidative phosphorylation may serve as novel agen