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Autor:
Alexander A. Pieper, Dan V. Spiegelman, Mildred A. R. Felder, Arika S. Feils, Noah W. Tsarovsky, Jen Zaborek, Zachary S. Morris, Amy K. Erbe, Alexander L. Rakhmilevich, Paul M. Sondel
Publikováno v:
Cancer Immunology, Immunotherapy.
Background The in-situ vaccine using CpG oligodeoxynucleotide combined with OX40 agonist antibody (CpG + OX40) has been shown to be an effective therapy activating an anti-tumor T cell response in certain settings. The roles of tumor volume, tumor mo