Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Mildred Ugozzoli"'
Autor:
Brunella Brunelli, Silvia Senesi, Michele Pallaoro, Mildred Ugozzoli, Derek T. O'Hagan, Francesca Ferlicca, Annalisa Colaprico
Publikováno v:
Vaccine. 38(19)
Aluminum based adjuvants are widely used in commercial vaccines, since they are known to be safe and effective with a variety of antigens. The effect of antigen adsorption onto Aluminum Hydroxide is a complex area, since several mechanisms are involv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c09721f3d201404b7822f0bb5cff3c1
https://pubmed.ncbi.nlm.nih.gov/32063436
https://pubmed.ncbi.nlm.nih.gov/32063436
Autor:
Derek T. O'Hagan, Stephanie Kay Dodd, Mildred Ugozzoli, Mansoor M. Amiji, Ruchi Rudraprasad Shah, Mary Schaefer, Gillis R. Otten, Luis Brito, Manmohan Singh
Publikováno v:
Journal of Pharmaceutical Sciences. 104:1352-1361
Microfluidization is an established technique for preparing emulsion adjuvant formulations for use in vaccines. Although this technique reproducibly yields high-quality stable emulsions, it is complex, expensive, and requires proprietary equipment. F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce28b41c36869e663db19000354d0754
https://doi.org/10.1002/jps.24337
https://doi.org/10.1002/jps.24337
Autor:
Oliver Koeberling, George Santos, John J. Donnelly, Mildred Ugozzoli, Dan M. Granoff, Anja Seubert, Annalisa Colaprico
Publikováno v:
Vaccine. 29:4728-4734
We previously investigated immunogenicity of meningococcal native outer membrane vesicle (NOMV) vaccines prepared from recombinant strains with attenuated endotoxin (ΔLpxL1) and over-expressed factor H binding protein (fHbp) in a mouse model. The va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8046c6267f4a82a5ff15fdfacabc27b8
https://doi.org/10.1016/j.vaccine.2011.04.095
https://doi.org/10.1016/j.vaccine.2011.04.095
Autor:
Manmohan Singh, Jina Kazzaz, Mildred Ugozzoli, Claire Madden, James Chesko, Derek T. O'Hagan, Nikin Patel, Mark Perkins
Publikováno v:
Journal of Pharmaceutical Sciences. 97:1443-1453
The chemical composition of the surface of anionic PLG microparticles before and after adsorption of vaccine antigens was measured using X-ray photoelectron spectroscopy (XPS) and time-of-flight secondary ion mass spectrometry (TOF-SIMS). The interfa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b74e1e734c965475c8917325e4cc9d1
https://doi.org/10.1002/jps.21040
https://doi.org/10.1002/jps.21040
Autor:
Mildred Ugozzoli, Simona Tavarini, Sandra Nuti, Manmohan Singh, Emanuele Montomoli, Barbara Baudner, Hanno Scheffczik, Jina Kazzaz, Rino Rappuoli, Andreas Wack, Ilaria Manini, Derek T. O'Hagan, Giuseppe Del Giudice, Anne Katrin Hilbert
Publikováno v:
Vaccine. 26:552-561
Influenza is controlled by protective titres of neutralizing antibodies, induced with the help of CD4 T-cells, and by antiviral T-cell effector function. Adjuvants are essential for the efficient vaccination of a naïve population against avian influ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed041173efa6f0829c750c51ad6ebc12
https://doi.org/10.1016/j.vaccine.2007.11.054
https://doi.org/10.1016/j.vaccine.2007.11.054
Autor:
Rebecca Wei, Jina Kazzaz, Raj Dhaliwal, Derek T. O'Hagan, James Chesko, Maninder S. Hora, Mildred Ugozzoli, Jia-Hwa Fang, Manmohan Singh, Padma Malyala
Publikováno v:
International Journal of Pharmaceutics. 327:1-5
We have previously shown that cationic polylactide-co-glycolide (PLG) microparticles can be effectively used to adsorb DNA and generate potent immune responses in vivo. We now describe a modified and easier process containing a single lyophilization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd9350c929e41fc77e3f87bfaf6cce66
https://doi.org/10.1016/j.ijpharm.2006.07.033
https://doi.org/10.1016/j.ijpharm.2006.07.033
Autor:
James Chesko, Manmohan Singh, Jina Kazzaz, Mildred Ugozzoli, Elawati Soenawan, Derek T. O'Hagan
Publikováno v:
Journal of Controlled Release. 110:566-573
Purpose: Monophosphoryl lipid A (MPL) and the synthetic LPS mimetic RC529, encapsulated in poly(lactide-co-glycolide) (PLG) microparticles, were evaluated as immune potentiators in the presence of either HIV-1 gp120 protein or antigen from Neisseria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dad2d103d7a20c4e71b7b036ea053cef
https://doi.org/10.1016/j.jconrel.2005.10.010
https://doi.org/10.1016/j.jconrel.2005.10.010
Autor:
Elawati Soenawan, Elena Pushnova, Amarjit Pannu, Mildred Ugozzoli, Derek T. O'Hagan, Manmohan Singh, Judith Allen
Publikováno v:
American Journal of Drug Delivery. 4:195-199
Plasmid DNA is currently being considered for immunization as an alternative approach to protein-based vaccines. The prevailing opinion is that the linear and open-circular forms of plasmid DNA are less effective than the supercoiled isoform in induc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6425bff9f58f9abfcba836264ea9492
https://doi.org/10.2165/00137696-200604040-00002
https://doi.org/10.2165/00137696-200604040-00002
Autor:
Derek T. O'Hagan, James Chesko, Mildred Ugozzoli, Jina Kazzaz, Manmohan Singh, Indresh K. Srivastava, Elaine Kan
Publikováno v:
Pharmaceutical Research. 21:2148-2152
To evaluate the delivery of a novel HIV-1 antigen (gp120dV2 SF162) by surface adsorption or encapsulation within polylactide-co-glycolide microparticles and to compare both the formulations for their ability to preserve functional activity as measure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19a1a2d04b91ea3fc8443430fb6f618b
https://doi.org/10.1007/s11095-004-7666-6
https://doi.org/10.1007/s11095-004-7666-6
Publikováno v:
Expert Opinion on Biological Therapy. 4:483-491
Polymeric microparticles with encapsulated antigens have become well-established in the last decade as potent antigen delivery systems and adjuvants, with experience being reported from many groups. However, the authors have recently shown that an al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3168ce6351fda01ce679242edf09ab24
https://doi.org/10.1517/14712598.4.4.483
https://doi.org/10.1517/14712598.4.4.483