Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Milda M. Burbuliene"'
Publikováno v:
ARKIVOC, Vol 2016, Iss 3, Pp 374-386 (2016)
Publikováno v:
Journal of Sulfur Chemistry. 33:403-411
Novel 1,3,4-oxadiazoles, 1,3,4-thiadiazoles and 1,2,4-triazole-3-thiones bearing the pyrimidinylthio- moiety were synthesized by cyclization of a substituted-thiosemicarbazide precursor under different conditions. The thiosemicarbazide intermediates
Publikováno v:
Journal of Heterocyclic Chemistry. 49:737-741
6-Methyl-2-methylthio-4-oxopyrimidin-3(4H)-yl)acetohydrazide on heating in benzylamine undergo cyclization to 8-methyl-2H-pyrimido[2,1-c][1,2,4]triazine-3,6(1H, 4H)-dione, which under treatment with bromine in glacial acetic acid was converted to 7-b
Publikováno v:
ARKIVOC, Vol 2010, Iss 11, Pp 39-48 (2010)
On nitrosation of (pyrimidin-4-yloxy)and (pyrimidin-3-yl)acetohydrazides 2, 3 with sodium nitrite in diluted hydrochloric acid at 0-5 °C the corresponding (pyrimidinyl)acetyl azides 5, 6 were prepared. Azides 5, 6 undergo Curtius rearrangement in th
Publikováno v:
Arkivoc. 2009:281-289
New 1,2,4-triazoles 3a,b, 4a,b, 1,3,4-oxadiazoles 5a,b, 1,3,4-thiadiazoles 6a,b and 4thiazolidinones 7a,b were synthesized by cyclization of N-substituted 2-[2-(6-methyl-2morpholinopyrimidin-4-ylthio)acetyl]hydrazinecarbothioamides 2a,b under differe
Publikováno v:
Journal of Heterocyclic Chemistry. 45:1391-1395
[2-Alkylthio-6-methyl-4-oxopyrimidin-3(4H)-yl]acetonitriles (3-5) treated with sodium methoxide in methanol followed by ammonium chloride were cyclized to 2-imino-7-methyl-2,3-dihydroimidazo[1,2-a]-pyrimidin-5(1H)-ones (6-8). Under acid or base-catal
Autor:
Romualdas Smicius, Milda M. Burbuliene, Virginija Jakubkienė, Emilija Udrwėnaitė, Povilas Vainilavicius
Publikováno v:
Journal of Heterocyclic Chemistry. 44:279-284
Various 4-amino-2,3-dihydro-4H-triazoles with aromatic, aliphatic and heterocyclic substituents at the C(5) position were synthesized from corresponding esters and thiocarbohydrazide. This method allows the synthesis these heterocycles in a short tim
Publikováno v:
Journal of Heterocyclic Chemistry. 43:43-47
Treatment of ambident sodium salt of 2-methylsulfanyl-4(3H)-quinazolinone with methyl bromoacetate resulted in N(3)-alkyl ester formation. Reaction of the resulted ester with hydrazine hydrate gave 2-methylsulfanyl-4-oxo-3(4H)-quinazolinyl)acetohydra
Autor:
E. Udrenaite, Romualdas Smicius, Virginija Jakubkiene, G. Mekuskiene, Povilas Vainilavicius, Milda M. Burbuliene
Publikováno v:
Il Farmaco. 59:767-774
Synthesis and results of anti-inflammatory activity in vivo of 5-[(2-disubstitutedamino-6-methyl-pyrimidin-4-yl)-sulfanylmethyl]-3H-1,3,4-oxadiazole-2-thiones and their S -alkyl-, N 3 -acyl- and N 3 -aminomethyl derivatives are described. All the tes
Publikováno v:
Phosphorus, Sulfur, and Silicon and the Related Elements. 178:2431-2440
Alkylation of 5-(4,6-dimethyl-2-pyrimidinylsulfanyl)methyl-1,2,4-triazole-3-thione (2) with various alkyl halides, 4-chlorophenacyl bromide, chloroacetic acid, and α-chloroacetanilide afforded S-substituted 1,2,4-triazoles (3–11). 3-Carboxymethyls