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pro vyhledávání: '"Milda Bartkeviciute"'
Autor:
Thomas Thibault, Daniel L. Rathbone, Milda Bartkeviciute, Colin E. Murdoch, Said El Alaoui, Eduard Badarau, Zhuo Wang, Martin Griffin, Andrea Costanzi
Publikováno v:
Chemistry & Biology. 22(10):1347-1361
SummaryPotent-selective peptidomimetic inhibitors of tissue transglutaminase (TG2) were developed through a combination of protein-ligand docking and molecular dynamic techniques. Derivatives of these inhibitors were made with the aim of specific TG2
Autor:
Sophie Broadway-Stringer, Camilla Siciliano, Colin E. Murdoch, Milda Bartkeviciute, Roberta Altobelli, Elena De Falco
Publikováno v:
Recent Patents on Regenerative Medicine. 4:149-167
Myocardial infarction results in loss of cardiac muscle and deficiency in cardiac performance. Likewise, peripheral artery disease can result in critical limb ischemia leading to reduced mobility, non-healing ulcers, gangrene and amputation. Both of
Publikováno v:
Free Radical Biology and Medicine. 108:S51
Introduction High soluble Flt1 (sFlt1) is pivotal in the development of ‘preeclampsia phenotype’ of hypertension and proteinuria. Disruption of endogenous protective pathways and increased oxidative stress are hallmarks.of preeclampsia. Yet the u