Construction and application of fetal loss risk model in systemic lupus erythematosus patients with mild disease severity

Autor: Yanran Chen, Yanjuan Chen, Bo Li, Wengyi Xu, Peipei Lei, Hongyang Liu, Dongzhou Liu, Xiaoping Hong

Publikováno v: BMC Pregnancy and Childbirth, Vol 24, Iss 1, Pp 1-13 (2024)

Abstract Background This dynamic nomogram model was developed to predict the probability of fetal loss in pregnant patients with systemic lupus erythematosus (SLE) with mild disease severity before conception. Methods An analysis was conducted on 314

Externí odkaz: https://doaj.org/article/624f954b693d4a55abc9f90bed120e4b

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

SMN1 c.5C>G (p.Ala2Gly) missense variant, a challenging molecular SMA diagnosis associated with mild disease, preserves SMN nuclear gems in patient-specific fibroblasts

Autor: Sara L. Cook, Christian Stout, Lindsey Kirkeby, Noemi Vidal-Folch, Devin Oglesbee, Linda Hasadsri, Duygu Selcen, Margherita Milone, Daniel Anderson, Nathan P. Staff

Publikováno v: Frontiers in Genetics, Vol 15 (2024)

IntroductionSpinal muscular atrophy (SMA) is caused by homozygous loss of the SMN1 gene with SMN2 gene copy number correlating with disease severity. Rarely SMA is caused by a deletion on one allele and a pathogenic variant on the other. The pathogen

Externí odkaz: https://doaj.org/article/3774c76d9a0d4d369a9106ee899bec86

Post-COVID fatigue: Reduced quality-of-life associated with clinically relevant fatigue in mild disease courses.

Autor: Biserni C; Department of Clinical and Developmental Neuropsychology, University of Groningen, Groningen, The Netherlands., De Groot BO; Department of Clinical and Developmental Neuropsychology, University of Groningen, Groningen, The Netherlands., Fuermaier ABM; Department of Clinical and Developmental Neuropsychology, University of Groningen, Groningen, The Netherlands., de Waard D; Department of Clinical and Developmental Neuropsychology, University of Groningen, Groningen, The Netherlands., Enriquez-Geppert S; Department of Clinical and Developmental Neuropsychology, University of Groningen, Groningen, The Netherlands.; Department of Biomedical Sciences of Cells & Systems, University Medical Center Groningen, Groningen, The Netherlands.

Publikováno v: Neuropsychological rehabilitation [Neuropsychol Rehabil] 2024 Oct; Vol. 34 (9), pp. 1302-1326. Date of Electronic Publication: 2024 Feb 21.

Effectiveness of inactivated COVID-19 vaccines against mild disease, pneumonia, and severe disease among persons infected with SARS-CoV-2 Omicron variant: real-world study in Jilin Province, China

Autor: Hongqin Xu, Hongyan Li, Hailong You, Peng Zhang, Nan Li, Nan Jiang, Yang Cao, Ling Qin, Guixiang Qin, Hongbo Qu, Heyuan Wang, Bo Zou, Xia He, Dan Li, Huazhong Zhao, Gang Huang, Yang Li, Hefeng Zhang, Liping Zhu, Hongmei Qiao, Hongjun Li, Shurong Liu, Lina Gu, Guidong Yin, Ye Hu, Songbai Xu, Weiying Guo, Nanya Wang, Chaoying Liu, Pujun Gao, Jie Cao, Yang Zheng, Kaiyu Zhang, Yang Wang, Hui Chen, Jian Zhang, Dongmei Mu, Junqi Niu

Publikováno v: Emerging Microbes and Infections, Vol 12, Iss 1 (2023)

ABSTRACTIt is critical to determine the real-world performance of vaccines against coronavirus disease 2019 (COVID-19) so that appropriate treatments and policies can be implemented. There was a rapid wave of infections by the Omicron variant in Jili

Externí odkaz: https://doaj.org/article/dc026477967446e7a000bd2774724d06