Analysis of memory B cells identifies conserved neutralizing epitopes on the N-terminal domain of variant SARS-Cov-2 spike proteins.

Autor: Wang Z; Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA., Muecksch F; Laboratory of Retrovirology, The Rockefeller University, New York, NY 10065, USA., Cho A; Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA., Gaebler C; Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA., Hoffmann HH; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY, USA., Ramos V; Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA., Zong S; Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA., Cipolla M; Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA., Johnson B; Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA., Schmidt F; Laboratory of Retrovirology, The Rockefeller University, New York, NY 10065, USA., DaSilva J; Laboratory of Retrovirology, The Rockefeller University, New York, NY 10065, USA., Bednarski E; Laboratory of Retrovirology, The Rockefeller University, New York, NY 10065, USA., Ben Tanfous T; Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA., Raspe R; Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA., Yao K; Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA., Lee YE; Department of Biology, Stanford University, Stanford, CA 94305, USA., Chen T; Department of Biology, Stanford University, Stanford, CA 94305, USA., Turroja M; Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA., Milard KG; Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA., Dizon J; Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA., Kaczynska A; Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA., Gazumyan A; Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA., Oliveira TY; Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA., Rice CM; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY, USA., Caskey M; Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA., Bieniasz PD; Laboratory of Retrovirology, The Rockefeller University, New York, NY 10065, USA; Howard Hughes Medical Institute, Chevy Chase, MD, USA. Electronic address: pbieniasz@rockefeller.edu., Hatziioannou T; Laboratory of Retrovirology, The Rockefeller University, New York, NY 10065, USA. Electronic address: thatziio@rockefeller.edu., Barnes CO; Department of Biology, Stanford University, Stanford, CA 94305, USA; Chan Zuckerberg Biohub, San Francisco, CA 94158, USA. Electronic address: cobarnes@stanford.edu., Nussenzweig MC; Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA; Howard Hughes Medical Institute, Chevy Chase, MD, USA. Electronic address: nussen@rockefeller.edu.

Publikováno v: Immunity [Immunity] 2022 Jun 14; Vol. 55 (6), pp. 998-1012.e8. Date of Electronic Publication: 2022 Apr 07.