Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Milan Sencanski"'
Autor:
Vladimir Perovic, Kristina Stevanovic, Natalya Bukreyeva, Slobodan Paessler, Junki Maruyama, Sergi López-Serrano, Ayub Darji, Milan Sencanski, Draginja Radosevic, Simone Berardozzi, Bruno Botta, Mattia Mori, Sanja Glisic
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 9, p 4911 (2024)
The influenza A virus nonstructural protein 1 (NS1), which is crucial for viral replication and immune evasion, has been identified as a significant drug target with substantial potential to contribute to the fight against influenza. The emergence of
Externí odkaz:
https://doaj.org/article/9eea7d0871e047f4a013bed4a1c970c9
Publikováno v:
Biomolecules, Vol 14, Iss 4, p 423 (2024)
This study assessed the suitability of the complementarity-determining region 2 (CDR2) of the nanobody (Nb) as a template for the derivation of nanobody-derived peptides (NDPs) targeting active-state β2-adrenergic receptor (β2AR) conformation. Sequ
Externí odkaz:
https://doaj.org/article/a2834c4a3f96422ba8ccea76a859eb4b
Autor:
Sara Protić, Nevena Kaličanin, Milan Sencanski, Olivera Prodanović, Jelena Milicevic, Vladimir Perovic, Slobodan Paessler, Radivoje Prodanović, Sanja Glisic
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 1955 (2023)
Finding an effective drug to prevent or treat COVID-19 is of utmost importance in tcurrent pandemic. Since developing a new treatment takes a significant amount of time, drug repurposing can be an effective option for achieving a rapid response. This
Externí odkaz:
https://doaj.org/article/f71856b854ad4c3fb905a17a91ab95a8
Autor:
Ivana Đukić, Nevena Kaličanin, Milan Sencanski, Snezana B. Pajovic, Jelena Milicevic, Jelena Prljic, Slobodan Paessler, Radivoje Prodanović, Sanja Glisic
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 28, Iss 1, p 8 (2023)
Background: Drug resistance is a critical problem in health care that affects therapy outcomes and requires new approaches to drug design. SARS-CoV-2 Mpro mutations are of concern as they can potentially reduce therapeutic efficacy. Viral infections
Externí odkaz:
https://doaj.org/article/bf2eb6013eb24f28b6e4b60f0def1ec7
Publikováno v:
Molecules, Vol 27, Iss 9, p 2626 (2022)
Alzheimer’s disease (AD), a devastating neurodegenerative disease, is the focus of pharmacological research. One of the targets that attract the most attention for the potential therapy of AD is the serotonin 5HT6 receptor, which is the receptor si
Externí odkaz:
https://doaj.org/article/cbab41fdeee343c89c8815e7d10eb088
Autor:
Draginja Radosevic, Milan Sencanski, Vladimir Perovic, Nevena Veljkovic, Jelena Prljic, Veljko Veljkovic, Emily Mantlo, Natalya Bukreyeva, Slobodan Paessler, Sanja Glisic
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 9 (2019)
Influenza A virus (IAV) matrix protein 2 (M2), an ion channel, is crucial for virus infection, and therefore, an important anti-influenza drug target. Adamantanes, also known as M2 channel blockers, are one of the two classes of Food and Drug Adminis
Externí odkaz:
https://doaj.org/article/6a8f96f097784cfeadf7ed06de607062
Autor:
Milan Sencanski, Vladimir Perovic, Snezana B. Pajovic, Miroslav Adzic, Slobodan Paessler, Sanja Glisic
Publikováno v:
Molecules, Vol 25, Iss 17, p 3830 (2020)
The SARS-CoV-2 outbreak caused an unprecedented global public health threat, having a high transmission rate with currently no drugs or vaccines approved. An alternative powerful additional approach to counteract COVID-19 is in silico drug repurposin
Externí odkaz:
https://doaj.org/article/c8d943499c0f47ea91dcc967dce73365
Autor:
Vera M. S. Isca, Milan Sencanski, Nenad Filipovic, Daniel J. V. A. Dos Santos, Ana Čipak Gašparović, Lucília Saraíva, Carlos A. M. Afonso, Patrícia Rijo, Alfonso T. García-Sosa
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 10, p 3671 (2020)
Plants have been used for centuries to treat several illnesses. The Plectranthus genus has a vast variety of species that has allowed the isolation of cytotoxic compounds with notable activities. The abietane diterpenes 6,7-dehydroroyleanone (DeRoy,
Externí odkaz:
https://doaj.org/article/ef82fd7468684f2d8db3d364438524ea
Autor:
Strahinja Stevanovic, Milan Sencanski, Mathieu Danel, Christophe Menendez, Roumaissa Belguedj, Abdelmalek Bouraiou, Katarina Nikolic, Sandrine Cojean, Philippe M. Loiseau, Sanja Glisic, Michel Baltas, Alfonso T. García-Sosa
Publikováno v:
Molecules, Vol 24, Iss 7, p 1282 (2019)
Due to the lack of approved vaccines against human leishmaniasis and the limitations of the current chemotherapy inducing side effects and drug resistance, development of new, effective chemotherapeutic agents is essential. This study describes the s
Externí odkaz:
https://doaj.org/article/df39e0b494e14ea1ae0280a0c717ab36
Autor:
Veljko Veljkovic, Marco Goeijenbier, Sanja Glisic, Nevena Veljkovic, Vladimir R. Perovic, Milan Sencanski, Donald R. Branch, Slobodan Paessler
Publikováno v:
F1000Research, Vol 4 (2015)
The large 2014/2015 Ebola virus outbreak in West Africa points out the urgent need to develop new preventive and therapeutic approaches that are effective against Ebola viruses and can be rapidly utilized. Recently, a simple theoretical criterion for
Externí odkaz:
https://doaj.org/article/62ca646f485f44a9a186dc068e32852c