Zobrazeno 1 - 10
of 169
pro vyhledávání: '"Milan Remko"'
Autor:
Joanna Bojarska, Roger New, Paweł Borowiecki, Milan Remko, Martin Breza, Izabela D. Madura, Andrzej Fruziński, Anna Pietrzak, Wojciech M. Wolf
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
Targeting the polyamine biosynthetic pathway by inhibiting ornithine decarboxylase (ODC) is a powerful approach in the fight against diverse viruses, including SARS-CoV-2. Difluoromethylornithine (DFMO, eflornithine) is the best-known inhibitor of OD
Externí odkaz:
https://doaj.org/article/63a96163d06546e89cb8ea59e6288086
Autor:
Vasso Apostolopoulos, Joanna Bojarska, Tsun-Thai Chai, Sherif Elnagdy, Krzysztof Kaczmarek, John Matsoukas, Roger New, Keykavous Parang, Octavio Paredes Lopez, Hamideh Parhiz, Conrad O. Perera, Monica Pickholz, Milan Remko, Michele Saviano, Mariusz Skwarczynski, Yefeng Tang, Wojciech M. Wolf, Taku Yoshiya, Janusz Zabrocki, Piotr Zielenkiewicz, Maha AlKhazindar, Vanessa Barriga, Konstantinos Kelaidonis, Elham Mousavinezhad Sarasia, Istvan Toth
Publikováno v:
Molecules, Vol 26, Iss 2, p 430 (2021)
Peptides are fragments of proteins that carry out biological functions. They act as signaling entities via all domains of life and interfere with protein-protein interactions, which are indispensable in bio-processes. Short peptides include fundament
Externí odkaz:
https://doaj.org/article/d2137ab22429462d894e99915a48f3f4
Autor:
Joanna Bojarska, Milan Remko, Martin Breza, Izabela Madura, Andrzej Fruziński, Wojciech M. Wolf
Publikováno v:
Pharmaceuticals, Vol 13, Iss 11, p 338 (2020)
Proline is a unique, endogenous amino acid, prevalent in proteins and essential for living organisms. It is appreciated as a tecton for the rational design of new bio-active substances. Herein, we present a short overview of the subject. We analyzed
Externí odkaz:
https://doaj.org/article/b4194ff8819840ad8bbcd2a3550f18fa
Autor:
Joanna Bojarska, Milan Remko, Martin Breza, Izabela D. Madura, Krzysztof Kaczmarek, Janusz Zabrocki, Wojciech M. Wolf
Publikováno v:
Molecules, Vol 25, Iss 5, p 1135 (2020)
The success of innovative drugs depends on an interdisciplinary and holistic approach to their design and development. The supramolecular architecture of living systems is controlled by non-covalent interactions to a very large extent. The latter are
Externí odkaz:
https://doaj.org/article/d778c51bf54c4fe0bfa2f182f417c111
Publikováno v:
Molecules, Vol 21, Iss 2, p 185 (2016)
The geometries and energies of factor Xa inhibitors edoxaban, eribaxaban, fidexaban, darexaban, letaxaban, and the dual factor Xa and thrombin inhibitors tanogitran and SAR107375 in both the gas-phase and aqueous solution were studied using the Becke
Externí odkaz:
https://doaj.org/article/7d2edf1e296040abb76eec66e1671683
Autor:
Joanna Bojarska, Martin Breza, Milan Remko, Ye Yuan, Zyta M. Ziora, Tsun-Thai Chai, Izabela D. Madura, Krzysztof Kaczmarek, Mark A.T. Blaskovich, Wojciech M. Wolf
Publikováno v:
Journal of Molecular Structure. 1288:135732
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::957abbc5f74fcfd2bf69b80c2a31d1f9
https://doi.org/10.1016/j.molstruc.2023.135732
https://doi.org/10.1016/j.molstruc.2023.135732
Autor:
Joanna Bojarska, Martin Breza, Milan Remko, Paweł Borowiecki, Andrzej Fruziński, Izabela D. Madura, Krzysztof Kaczmarek, Zbigniew Leśnikowski, Agata Kraj, Piotr Zielenkiewicz, Wojciech M. Wolf
Publikováno v:
CrystEngComm. 24:8372-8389
Experimental–computational study of five novel cyclopropyl-containing peptide-derived compounds is focussed on the synthons preferences in (bio)supramolecular architecture. As a bonus, the promising activity of new molecules against prostate cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3fd25414f89c374d3e710d89aaecdba
https://doi.org/10.1039/d2ce01231f
https://doi.org/10.1039/d2ce01231f
Autor:
Joanna Bojarska, Martin Breza, Milan Remko, Malgorzata Czyz, Anna Gajos-Michniewicz, Michał Zimecki, Krzysztof Kaczmarek, Izabela D. Madura, Jakub M. Wojciechowski, Wojciech M. Wolf
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 13; Pages: 7173
Short peptides have great potential as safe and effective anticancer drug leads. Herein, the influence of short cyclic peptides containing the Pro-Pro-Phe-Phe sequence on patient-derived melanoma cells was investigated. Cyclic peptides such as cyclo(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7e6fb2dd89847fdac7175f1f703177b
Autor:
Bojarska Joanna, Anna Anna Gajos-Michniewicz, Malgorzata Czyz, Piotr Zielenkiewicz, Krzysztof Kaczmarek, Michał Zimecki, Milan Remko, Martin Breza, Izabela Madura, Jakub Wojciechowski, Wojciech Wolf
Publikováno v:
Proceedings of 7th International Electronic Conference on Medicinal Chemistry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02705af58c809300839a7189c693f4a7
https://doi.org/10.3390/ecmc2021-11599
https://doi.org/10.3390/ecmc2021-11599
Autor:
Joanna Bojarska, Janusz Zabrocki, Krzysztof Kaczmarek, Andrzej Olczak, Jakub Wojciechowski, Izabela D. Madura, Wojciech M. Wolf, Milan Remko
Publikováno v:
Journal of Molecular Structure. 1190:11-22
The title compound, N-benzoyl-2′-hydroxy-3-methylisovaline, representing synthon polymorphism, can be interesting inter alia from the point of view of modern supramolecular biofunctional materials. A novel crystalline phase (1) was successfully syn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37629ae153da1c3ac58f8abf3cb79b30
https://doi.org/10.1016/j.molstruc.2019.04.045
https://doi.org/10.1016/j.molstruc.2019.04.045