Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Milan Reiniš"'
Autor:
Zofia Chrienova, David Rysanek, Patrik Oleksak, Dorota Stary, Marek Bajda, Milan Reinis, Romana Mikyskova, Ondrej Novotny, Rudolf Andrys, Adam Skarka, Pavla Vasicova, Josef Novak, Martin Valis, Kamil Kuca, Zdenek Hodny, Eugenie Nepovimova
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
To date, the most studied drug in anti-aging research is the mTOR inhibitor – rapamycin. Despite its almost perfect anti-aging profile, rapamycin exerts one significant limitation – inappropriate physicochemical properties. Therefore, we have dec
Externí odkaz:
https://doaj.org/article/2138141c119d4080852852773bb5684e
Autor:
Patrik Oleksak, Miroslav Psotka, Marketa Vancurova, Olena Sapega, Jana Bieblova, Milan Reinis, David Rysanek, Romana Mikyskova, Katarina Chalupova, David Malinak, Jana Svobodova, Rudolf Andrys, Helena Rehulkova, Vojtech Skopek, Pham Ngoc Lam, Jiri Bartek, Zdenek Hodny, Kamil Musilek
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 410-424 (2021)
Twelve novel analogs of STAT3 inhibitor BP-1-102 were designed and synthesised with the aim to modify hydrophobic fragments of the molecules that are important for interaction with the STAT3 SH2 domain. The cytotoxic activity of the reference and nov
Externí odkaz:
https://doaj.org/article/cfac0c0e4320428ab38cfae14e7c28f8
Autor:
Romana Mikyskova, Marie Indrova, Ivan Stepanek, Ivan Kanchev, Jana Bieblova, Sarka Vosahlikova, Irena Moserova, Iva Truxova, Jitka Fucikova, Jirina Bartunkova, Radek Spisek, Radislav Sedlacek, Milan Reinis
Publikováno v:
OncoImmunology, Vol 6, Iss 12 (2017)
Dendritic cell (DC)-based vaccines pulsed with high hydrostatic pressure (HHP)-inactivated tumor cells have recently been shown to be a promising tool for prostate cancer chemoimmunotherapy. In this study, DC-based vaccines, both pulsed and unpulsed,
Externí odkaz:
https://doaj.org/article/006b9b47062f4a4db63aa21dfef94d7d
Autor:
Martina Koncošová, Michaela Rumlová, Romana Mikyšková, Milan Reiniš, Jaroslav Zelenka, Tomáš Ruml, Kaplan Kirakci, Kamil Lang
Publikováno v:
Journal of Materials Chemistry B. 10:3303-3310
X-Ray-induced photodynamic therapy represents a suitable modality for the treatment of various malignancies. It is based on the production of reactive oxygen species by radiosensitizing nanoparticles activated by X-rays. Hence, it allows overcoming t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::107777b0ef87d34f1af50cc247572823
https://doi.org/10.1039/d2tb00141a
https://doi.org/10.1039/d2tb00141a
Autor:
Filip Novotny, Rastislav Dzijak, Ivan Stepanek, Filip Havel, Andrea Babelova, Michal Sramek, Monika Zarska, Kamil Musilek, Jiri Bartek, Ondrej Novak, J. Proska, Blanka Mrazkova, Monika Ursinyova, Zdenek Hodny, Oldrich Benada, Milan Reiniš, Kamil Kuca
Publikováno v:
Biomaterials
The exceptionally high cellular uptake of gold nanorods (GNRs) bearing cationic surfactants makes them a promising tool for biomedical applications . Given the known specific toxic and stress effects of some preparations of cationic nanoparticles, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::854ea23bbe563622456754704e48c231
https://doi.org/10.1016/j.biomaterials.2017.10.044
https://doi.org/10.1016/j.biomaterials.2017.10.044
Autor:
Jiri Bartek, Jana Símová, Romana Mikyšková, Lenka Kyjacova, Terezie Imrichova, Olena Sapega, Jana Bieblová, Marie Indrová, Zdenek Hodny, Ivan Stepanek, Milan Reiniš, Jan Bubenik
Publikováno v:
Oncotarget
// Jana Simova 1 , Olena Sapega 1 , Terezie Imrichova 2 , Ivan Stepanek 1 , Lenka Kyjacova 2 , Romana Mikyskova 1 , Marie Indrova 1 , Jana Bieblova 1 , Jan Bubenik 3 , Jiri Bartek 2, 4, 5 , Zdenek Hodny 2 , Milan Reinis 1 1 Immunology Unit, Czech Cen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0471a7abff977f8d8d4a9906fd45fec
https://doi.org/10.18632/oncotarget.10712
https://doi.org/10.18632/oncotarget.10712
Autor:
Guy de Martynoff, Nada Hradilova, David Bechard, Romana Mikyšková, Ulrich Moebius, Milan Reiniš, Radek Spisek, Irena Adkins
Publikováno v:
Cancer Research. 80:6686-6686
SO-C101 (RLI-15) is a superagonist fusion protein of interleukin (IL)-15 and the IL-15 receptor α (IL-15Rα) sushi+ domain designed to bypass the need of endogenous IL-15Rα, thereby leveraging the activity of IL-15 in vivo on target immune cells an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7dd49acfe3e1579be72d34c9c098e7c
https://doi.org/10.1158/1538-7445.am2020-6686
https://doi.org/10.1158/1538-7445.am2020-6686
Autor:
Sarka Vosahlikova, Jarmila Králová, Milan Reiniš, Irena Moserova, Romana Mikyšková, Jitka Fucikova
Publikováno v:
Cancer Immunology Research. 8:B35-B35
Photodynamic therapy (PDT) has attracted great attention in cancer treatment. Porphyrin derivative with ethylene glycol chains linked to meta position of meso-tetraphenylporphyrin, mTPP(EG)4, is one of assumed compounds that can be used for treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f11ff9c4fa844f78491b8480d9fc7521
https://doi.org/10.1158/2326-6074.tumimm18-b35
https://doi.org/10.1158/2326-6074.tumimm18-b35
Autor:
Pavla Bilkova, Lorenzo Galluzzi, Michal Hensler, Peter Holicek, Milan Reiniš, Xiufen Chen, Monika Holubova, Marek Kovar, Barbora Tomalova, Justin Kline, Iva Truxova, Radek Spisek, Daniel Lysák, Jitka Fucikova, Lenka Kasikova, Cyril Salek, Romana Mikyšková
Publikováno v:
Cancer Immunology Research. 8:B96-B96
In some settings, cancer cells responding to treatment undergo an immunogenic form of cell death that is associated with the abundant emission of danger signals in the form of damage-associated molecular patterns (DAMPs). Accumulating preclinical and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd60c409c11f54f237f7e353b187094d
https://doi.org/10.1158/2326-6074.tumimm19-b96
https://doi.org/10.1158/2326-6074.tumimm19-b96
Publikováno v:
International Journal of Oncology
Cellular senescence is the process of the permanent proliferative arrest of cells in response to various inducers. It is accompanied by typical morphological changes, in addition to the secretion of bioactive molecules, including proinflammatory cyto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c79db5e2b2acf288f046ebc3e10e8374
https://doi.org/10.3892/ijo.2018.4553
https://doi.org/10.3892/ijo.2018.4553