Zobrazeno 1 - 10
of 160
pro vyhledávání: '"Milan Raska"'
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-16 (2024)
Abstract Human immunodeficiency virus type 1 (HIV-1) vaccine immunogens capable of inducing broadly neutralizing antibodies (bNAbs) remain obscure. HIV-1 evades immune responses through enormous diversity and hides its conserved vulnerable epitopes o
Externí odkaz:
https://doaj.org/article/188eec09a91b4c02873a0e0284bafd18
Autor:
Kristyna Sloupenska, Barbora Koubkova, Pavel Horak, Jana Dolezilkova, Beata Hutyrova, Mojmir Racansky, Martina Miklusova, Jan Mares, Milan Raska, Michal Krupka
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Borrelia burgdorferi sensu lato is a species complex of pleomorphic spirochetes, including species that cause Lyme disease (LD) in humans. In addition to classic spiral forms, these bacteria are capable of creating morphological forms referr
Externí odkaz:
https://doaj.org/article/21933d397dca45289db44ab2d440c04a
Autor:
Leona Raskova Kafkova, Joanna M. Mierzwicka, Prosenjit Chakraborty, Petr Jakubec, Ondrej Fischer, Jozef Skarda, Petr Maly, Milan Raska
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Non-small cell lung cancer (NSCLC) is largely promoted by a multistep tumorigenesis process involving various genetic and epigenetic alterations, which essentially contribute to the high incidence of mortality among patients with NSCLC. Clinical obse
Externí odkaz:
https://doaj.org/article/9ea9c310c79145f588c8e0fcd68b2a5b
Autor:
Jana Jemelkova, Milada Stuchlova Horynova, Petr Kosztyu, Katerina Zachova, Josef Zadrazil, Dana Galuszkova, Kazuo Takahashi, Jan Novak, Milan Raska
Publikováno v:
Kidney International Reports, Vol 8, Iss 5, Pp 1068-1075 (2023)
Introduction: Immunoglobulin A1 (IgA1) with galactose-deficient O-glycans (Gd-IgA1) play a key role in the pathogenesis of IgA nephropathy (IgAN). Mucosal-tissue infections increase IL-6 production and, in patients with IgAN, are often associated wit
Externí odkaz:
https://doaj.org/article/9f298502b83846878de889d7aa0b4ecc
Autor:
Maryna Golovchenko, Jakub Opelka, Marie Vancova, Hana Sehadova, Veronika Kralikova, Martin Dobias, Milan Raska, Michal Krupka, Kristyna Sloupenska, Natalie Rudenko
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 16906 (2023)
Lyme disease (LD) spirochetes are well known to be able to disseminate into the tissues of infected hosts, including humans. The diverse strategies used by spirochetes to avoid the host immune system and persist in the host include active immune supp
Externí odkaz:
https://doaj.org/article/58a8a6dace67427588f77d2f88c1c3a6
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IgA nephropathy (IgAN) is an autoimmune disease in which poorly galactosylated IgA1 is the antigen recognized by naturally occurring anti-glycan antibodies, leading to formation of nephritogenic circulating immune complexes. Incidence of IgAN display
Externí odkaz:
https://doaj.org/article/bb7e6d959cc84ddbb8726035db2e82cc
Autor:
Eva Kriegova, Regina Fillerova, Milan Raska, Jirina Manakova, Martin Dihel, Ondrej Janca, Pavel Sauer, Martina Klimkova, Petra Strakova, Petr Kvapil
Publikováno v:
Virology Journal, Vol 18, Iss 1, Pp 1-9 (2021)
Abstract The early identification of asymptomatic yet infectious cases is vital to curb the 2019 coronavirus (COVID-19) pandemic and to control the disease in the post-pandemic era. In this paper, we propose a fast, inexpensive and high-throughput ap
Externí odkaz:
https://doaj.org/article/eca14eaa4ae64780966cf675d2e4ca26
Publikováno v:
Pathology and Oncology Research, Vol 28 (2022)
Colorectal cancer (CRC) is one of the most common cancers worldwide. The patient’s prognosis largely depends on the tumor stage at diagnosis. The pathological TNM Classification of Malignant Tumors (pTNM) staging of surgically resected cancers repr
Externí odkaz:
https://doaj.org/article/0514f6572afe4a9fb8c4ee358319dcae
Autor:
Kristyna Sloupenska, Barbora Koubkova, Pavel Horak, Beata Hutyrova, Mojmir Racansky, Jan Mares, Martina Miklusova, Jan Schovanek, Jana Zapletalova, Milan Raska, Michal Krupka
Publikováno v:
Life, Vol 13, Iss 2, p 527 (2023)
Most patients suffering from Lyme disease are effectively treated with antibiotics. In some patients, however, problems persist for a long time despite appropriate therapy. The term post-treatment Lyme disease syndrome (PTLDS) is currently used for t
Externí odkaz:
https://doaj.org/article/875f1e6c99a645c2b1849e827d407852
Autor:
Katerina Zachova, Petr Kosztyu, Josef Zadrazil, Karel Matousovic, Karel Vondrak, Petr Hubacek, Klara Kostovcikova, Helena Tlaskalova Hogenova, Jiri Mestecky, Milan Raska
Publikováno v:
Biomedical Papers, Vol 164, Iss 3, Pp 247-254 (2020)
Aims: Epstein-Barr virus (EBV) targets predominantly B cells and these cells could acquire new phenotype characteristics. Here we analyzed whether EBV-infected and -uninfected B cells from healthy subjects differ in proportion of dominant phenotypes,
Externí odkaz:
https://doaj.org/article/c79a8d1ab0aa4c6e86eb7fbfa9d9721e