Zobrazeno 1 - 10
of 182
pro vyhledávání: '"Milan Jirsa"'
Publikováno v:
Discover Nano, Vol 19, Iss 1, Pp 1-31 (2024)
Abstract In recent years, it has been recognized that mechanical forces play an important regulative role in living organisms and possess a direct impact on crucial cell functions, ranging from cell growth to maintenance of tissue homeostasis. Advanc
Externí odkaz:
https://doaj.org/article/d58b5e8832d5452fbd3b9affa545b131
Publikováno v:
Biomaterials and Biosystems, Vol 14, Iss , Pp 100093- (2024)
Recently, it has been recognized that physical abnormalities (e.g. elevated solid stress, elevated interstitial fluid pressure, increased stiffness) are associated with tumor progression and development. Additionally, these mechanical forces originat
Externí odkaz:
https://doaj.org/article/86b2fcf438c445768b98bc6786088965
Autor:
Kateryna Levada, Stanislav Pshenichnikov, Alexander Omelyanchik, Valeria Rodionova, Aleksey Nikitin, Alexander Savchenko, Igor Schetinin, Dmitry Zhukov, Maxim Abakumov, Alexander Majouga, Mariia Lunova, Milan Jirsa, Barbora Smolková, Mariia Uzhytchak, Alexandr Dejneka, Oleg Lunov
Publikováno v:
Nano Convergence, Vol 7, Iss 1, Pp 1-17 (2020)
Abstract Iron oxide nanoparticles (IONs) are frequently used in various biomedical applications, in particular as magnetic resonance imaging contrast agents in liver imaging. Indeed, number of IONs have been withdrawn due to their poor clinical perfo
Externí odkaz:
https://doaj.org/article/e2a10a901a284e2e8648dc717bffd2b0
Autor:
Dita Musalkova, Filip Majer, Ladislav Kuchar, Ondrej Luksan, Befekadu Asfaw, Hana Vlaskova, Gabriela Storkanova, Martin Reboun, Helena Poupetova, Helena Jahnova, Helena Hulkova, Jana Ledvinova, Lenka Dvorakova, Jakub Sikora, Milan Jirsa, Marie T. Vanier, Martin Hrebicek
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 15, Iss 1, Pp 1-12 (2020)
Abstract Background Niemann-Pick type C (NP-C) is a rare neurovisceral genetic disorder caused by mutations in the NPC1 or the NPC2 gene. NPC1 is a multipass-transmembrane protein essential for egress of cholesterol from late endosomes/lysosomes. To
Externí odkaz:
https://doaj.org/article/031fa5ce876346a8afddbb9efd991352
Autor:
Eva Sticova, Milan Jirsa
Publikováno v:
Annals of Hepatology, Vol 19, Iss 2, Pp 126-133 (2020)
ATP-binding cassette (ABC) subfamily B member 4 (ABCB4), also known as multidrug resistance protein 3 (MDR3), encoded by ABCB4, is involved in biliary phospholipid secretion, protecting hepatobiliary system from deleterious detergent and lithogenic p
Externí odkaz:
https://doaj.org/article/94ace5d8dd8c41c38d53594c46ad430b
Publikováno v:
Biomedical Papers, Vol 164, Iss 1, Pp 121-125 (2020)
Introduction: Progressive familial intrahepatic cholestasis type 3 (PFIC3) is a rare autosomal recessive cholestatic liver disorder caused by genetic deficiency of ATP-binding cassette subfamily B member 4 (ABCB4), a hepatocanalicular floppase transl
Externí odkaz:
https://doaj.org/article/bfb4f565e97844fe8144cda353d78d9c
Autor:
Barbora Smolková, Mariia Lunova, Anna Lynnyk, Mariia Uzhytchak, Olexander Churpita, Milan Jirsa, Šárka Kubinová, Oleg Lunov, Alexandr Dejneka
Publikováno v:
Cellular Physiology and Biochemistry, Vol 52, Iss 1, Pp 119-140 (2019)
Externí odkaz:
https://doaj.org/article/73bc96229e4046489b1a5d329884a1f1
Autor:
Sona Frankova, Mariia Lunova, Halima Gottfriedova, Renata Senkerikova, Magdalena Neroldova, Jozef Kovac, Eva Kieslichova, Vera Lanska, Petr Urbanek, Julius Spicak, Milan Jirsa, Jan Sperl
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0244934 (2021)
Liver stiffness is a reliable non-invasive predictor of Hepatic Venous Pressure Gradient (HVPG) above 10 mm Hg. However, it failed to predict higher thresholds of HVPG. Our aim was to investigate whether liver stiffness and selected previously publis
Externí odkaz:
https://doaj.org/article/15693fbee5f54d4c829a6be9e98c6fb3
Autor:
Zuzana Rabekova, Sona Frankova, Milan Jirsa, Magdalena Neroldova, Mariia Lunova, Ondrej Fabian, Martin Kveton, David Varys, Klara Chmelova, Vera Adamkova, Jaroslav A. Hubacek, Julius Spicak, Dusan Merta, Jan Sperl
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 19, p 10560 (2021)
Heterozygotes for Z or S alleles of alpha-1-antrypsin (AAT) have low serum AAT levels. Our aim was to compare the risk of hepatocellular carcinoma (HCC) in patients with liver cirrhosis carrying the SERPINA1 MM, MZ and MS genotypes. The study groups
Externí odkaz:
https://doaj.org/article/49eab070c381406e9edb45a152ff0b01
Autor:
Oleg Lunov, Vitalii Zablotskii, Olexander Churpita, Mariia Lunova, Milan Jirsa, Alexandr Dejneka, Šárka Kubinová
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Abstract A rigorous biochemical analysis of interactions between non-thermal plasmas (NTPs) and living cells has become an important research topic, due to recent developments in biomedical applications of non-thermal plasmas. Here, we decouple disti
Externí odkaz:
https://doaj.org/article/c61cc329adb748a786c91705bc13e614