Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Milan, Zachrdla"'
Autor:
Nicolas Bolik-Coulon, Milan Zachrdla, Guillaume Bouvignies, Philippe Pelupessy, Fabien Ferrage
Relaxometry consists in measuring relaxation rates over orders of magnitude of magnetic fields to probe motions of complex systems. High-resolution relaxometry (HRR) experiments can be performed on conventional high-field NMR magnets equipped with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72ef2f5164f4449e4a8c7c62cf98dcba
https://doi.org/10.26434/chemrxiv-2023-b8qn6
https://doi.org/10.26434/chemrxiv-2023-b8qn6
Autor:
Nicola, Salvi, Vojtěch, Zapletal, Zuzana, Jaseňáková, Milan, Zachrdla, Petr, Padrta, Subhash, Narasimhan, Thorsten, Marquardsen, Jean-Max, Tyburn, Lukáš, Žídek, Martin, Blackledge, Fabien, Ferrage, Pavel, Kadeřávek
Publikováno v:
Biophysical Journal
Biophysical Journal, 2022, 121 (20), pp.3785-3794. ⟨10.1016/j.bpj.2022.09.016⟩
Biophysical Journal, 2022, 121 (20), pp.3785-3794. ⟨10.1016/j.bpj.2022.09.016⟩
International audience; Intrinsically disordered proteins (IDPs) or intrinsically disordered regions (IDRs) is a class of biologically important proteins exhibiting specific biophysical characteristics. They lack a hydrophobic core, and their conform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5898807fff2dd8639a7294778ef9a36
https://hal.science/hal-03861375/file/Salvi_BJ_text_preaccepted_4FF.pdf
https://hal.science/hal-03861375/file/Salvi_BJ_text_preaccepted_4FF.pdf
Autor:
Milan Zachrdla, Adriana Savastano, Alain Ibáñez de Opakua, Maria‐Sol Cima‐Omori, Markus Zweckstetter
Publikováno v:
Protein science 31(9), e4409 (2022). doi:10.1002/pro.4409
Protein Science
Protein Science
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleocapsid protein is an essential structural component of mature virions, encapsulating the genomic RNA and modulating RNA transcription and replication. Several of its activities might
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aa0ec06e52896c342e00805d62e582e
https://pubmed.ncbi.nlm.nih.gov/36040256
https://pubmed.ncbi.nlm.nih.gov/36040256
Autor:
Nicolas Bolik-Coulon, Olivier Languin-Cattoën, Diego Carnevale, Milan Zachrdla, Damien Laage, Fabio Sterpone, Guillaume Stirnemann, Fabien Ferrage
Publikováno v:
Physical Review Letters
Physical Review Letters, 2022, 129 (20), pp.203001. ⟨10.1103/PhysRevLett.129.203001⟩
Physical Review Letters, 2022, 129 (20), pp.203001. ⟨10.1103/PhysRevLett.129.203001⟩
International audience; Nuclear magnetic relaxation is widely used to probe protein dynamics. For decades, most analyses of relaxation in proteins have relied successfully on the model-free approach, forgoing mechanistic descriptions of motions. Mode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::860bef531d5d3dbacc1ac41f601adf08
http://arxiv.org/abs/2204.05813
http://arxiv.org/abs/2204.05813
Autor:
Milan Zachrdla, Adriana Savastano, Alain Ibáñez de Opakua, Maria-Sol Cima-Omori, Markus Zweckstetter
SARS-CoV-2 nucleocapsid protein is an essential structural component of mature virions, encapsulating the genomic RNA and modulating RNA transcription and replication. Several of its activities might be associated with the protein’s ability to unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7e645cc411669b1133a330f236f7f48
https://doi.org/10.1101/2022.03.30.486418
https://doi.org/10.1101/2022.03.30.486418
Autor:
Christopher A MacRaild, Milan Zachrdla, Dean Andrew, Bankala Krishnarjuna, Jiří Nováček, Lukáš Žídek, Vladimír Sklenář, Jack S Richards, James G Beeson, Robin F Anders, Raymond S Norton
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119899 (2015)
Merozoite surface protein 2 (MSP2) of Plasmodium falciparum is an abundant, intrinsically disordered protein that is GPI-anchored to the surface of the invasive blood stage of the malaria parasite. Recombinant MSP2 has been trialled as a component of
Externí odkaz:
https://doaj.org/article/6ccae8c4810c405e905cd97c80ea7865
Autor:
Veronica Ghini, Pavel Kaderavek, Fabien Ferrage, Jean-Max Tyburn, Guillaume Bouvignies, Thorsten Marquardsen, Morgan Kazmierczak, Ziqing Wang, Claudio Luchinat, Philippe Pelupessy, Giacomo Parigi, Simone Pisano, Milan Zachrdla
Publikováno v:
ChemRxiv
In this manuscript, we introduce an NMR method to investigate the interaction of metabolites and other small molecules with proteins in biological fluids. Our approach, based on high-resolution relaxometry identifies the interaction of small molecule
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9037cf22d773f6470f49eeb112bdf146
https://doi.org/10.26434/chemrxiv.13603301
https://doi.org/10.26434/chemrxiv.13603301
Autor:
Jean-Max Tyburn, Simone Pisano, Ziqing Wang, Veronica Ghini, Philippe Pelupessy, Morgan Kazmierczak, Giacomo Parigi, Thorsten Marquardsen, Fabien Ferrage, Guillaume Bouvignies, Claudio Luchinat, Pavel Kadeřávek, Milan Zachrdla
Publikováno v:
Journal of the American Chemical Society
Journal of the American Chemical Society, 2021, 143 (25), pp.9393-9404. ⟨10.1021/jacs.1c01388⟩
Journal of the American Chemical Society, American Chemical Society, 2021, 143 (25), pp.9393-9404. ⟨10.1021/jacs.1c01388⟩
Journal of the American Chemical Society, 2021, 143 (25), pp.9393-9404. ⟨10.1021/jacs.1c01388⟩
Journal of the American Chemical Society, American Chemical Society, 2021, 143 (25), pp.9393-9404. ⟨10.1021/jacs.1c01388⟩
International audience; Metabolomics, the systematic investigation of metabolites in biological fluids, cells or tissues, reveals essential information about metabolism and diseases. Metabolites have functional roles in myriads of biological processe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e27d857dcf4ff404cd91fcd28b3f84c8
Autor:
Ivan V. Zhukov, Alexey S. Kiryutin, Ziqing Wang, Milan Zachrdla, Alexandra V. Yurkovskaya, Konstantin L. Ivanov, Fabien Ferrage
Publikováno v:
Magnetic Resonance
Magnetic Resonance, Copernicus Publications, 2020, 1 (2), pp.237-246. ⟨10.5194/mr-1-237-2020⟩
Magnetic Resonance, Copernicus Publications, 2020, 1 (2), pp.237-246. ⟨10.5194/mr-1-237-2020⟩
Strong coupling of nuclear spins, which is achieved when their scalar coupling 2πJ is greater than or comparable to the difference δω in their Larmor precession frequencies in an external magnetic field, gives rise to efficient coherent longitudin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::247758ced9ecca41e93ff58fce58f7dd
https://doi.org/10.5194/mr-2020-14
https://doi.org/10.5194/mr-2020-14
Autor:
Jean-Max Tyburn, Vojtěch Zapletal, Milan Zachrdla, Nicolas Bolik-Coulon, Pavel Kadeřávek, Petr Padrta, Zuzana Jaseňáková, Thorsten Marquardsen, Fabien Ferrage, Lukáš Žídek
Publikováno v:
Journal of Biomolecular NMR
Journal of Biomolecular NMR, 2020, 74 (2-3), pp.139-145. ⟨10.1007/s10858-019-00298-6⟩
Journal of Biomolecular NMR, Springer Verlag, 2020, 74 (2-3), pp.139-145. ⟨10.1007/s10858-019-00298-6⟩
Journal of Biomolecular NMR, 2020, 74 (2-3), pp.139-145. ⟨10.1007/s10858-019-00298-6⟩
Journal of Biomolecular NMR, Springer Verlag, 2020, 74 (2-3), pp.139-145. ⟨10.1007/s10858-019-00298-6⟩
Improving our understanding of nanosecond motions in disordered proteins requires the enhanced sampling of the spectral density function obtained from relaxation at low magnetic fields. High-resolution relaxometry and two-field NMR measurements of re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90dcc5a617604f244d5912c64a7b4cde
https://doi.org/10.1007/s10858-019-00298-6
https://doi.org/10.1007/s10858-019-00298-6