Výsledky vyhledávání - "Milagros Pinilla"

Akademický článek

Identification of new splice sites used for generation of rev transcripts in human immunodeficiency virus type 1 subtype C primary isolates.

Autor: Elena Delgado, Cristina Carrera, Paloma Nebreda, Aurora Fernández-García, Milagros Pinilla, Valentina García, Lucía Pérez-Álvarez, Michael M Thomson

Publikováno v: PLoS ONE, Vol 7, Iss 2, p e30574 (2012)

The HIV-1 primary transcript undergoes a complex splicing process by which more than 40 different spliced RNAs are generated. One of the factors contributing to HIV-1 splicing complexity is the multiplicity of 3' splice sites (3'ss) used for generati

Externí odkaz: https://doaj.org/article/4deffcb05f724616ac36a38de0ec3273

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Improvement of HIV-1 coreceptor tropism prediction by employing selected nucleotide positions of the env gene in a Bayesian network classifier

Autor: Aurora Fernández-García, Lucía Pérez-Álvarez, Elena Delgado, Valentina García, Francisco Díez-Fuertes, María Teresa Cuevas, Yolanda Vega, Milagros Pinilla, Michael M. Thomson

Publikováno v: Journal of Antimicrobial Chemotherapy. 68:1471-1485

OBJECTIVES This study aimed to develop a genotypic method to predict HIV-1 coreceptor usage by employing the nucleotide sequence of the env gene in a tree-augmented naive Bayes (TAN) classifier, and to evaluate its accuracy in prediction compared wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6ad68c357aa902ab93b521ddd976db0
https://doi.org/10.1093/jac/dkt077

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Development of a Panel of Well-Characterized Human Immunodeficiency Virus Type 1 Isolates from Newly Diagnosed Patients Including Acute and Recent Infections

Autor: Mercedes Muñoz-Nieto, Thomson Mm, E. Serrano-Bengoechea, G. Contreras, Elena Delgado, Rafael Nájera, Lucía Pérez-Álvarez, María Teresa Cuevas, Antonio Ocampo, M. González-Galeano, Aurora Fernández-García, Valentina García, Milagros Pinilla, María Jesús Lezaun

Publikováno v: AIDS Research and Human Retroviruses. 25:93-102

The aim of this study was the development of a panel constituted by well-defined HIV-1 strains of different genetic forms, with a particular focus on isolates from acute and recent infections. Fourteen HIV-1 isolates, including four from acute and fi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aab9a31f2b60936f6f7484ea48491e45
https://doi.org/10.1089/aid.2008.0174

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Long-term monitoring of genotypic and phenotypic resistance to T20 in treated patients infected with HIV-1

Autor: Rocío Carmona, Rafael Nájera, Taboada Ja, S. Pérez de Castro, Lucía Pérez-Álvarez, Milagros Pinilla, Antonio Ocampo, Celia Miralles, G. Contreras, A. Asorey

Publikováno v: Journal of Medical Virology. 78:141-147

The aim of this study was to investigate the susceptibility to T20 and the dynamics of amino acid changes in HR1 and HR2 of gp41 of HIV-1 obtained from plasma, peripheral blood mononuclear cells (PBMC), and primary isolates (PI) in four highly antire

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::511a899ae888959fdc4a06c8bc467c67
https://doi.org/10.1002/jmv.20520

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Evaluation of genotypic tropism prediction tests compared with in vitro co-receptor usage in HIV-1 primary isolates of diverse subtypes

Autor: Ana Maria Sánchez, Valentina García, Michael M. Thomson, Lucía Pérez-Álvarez, Yolanda Vega, María José Cazorla González, Aurora Fernández-García, Mónica Sánchez, Teresa Cuevas, Milagros Pinilla, Elena Delgado

Publikováno v: The Journal of antimicrobial chemotherapy. 67(1)

To evaluate the sensitivity and specificity of genotypic methods for predicting the co-receptor usage of subtypes B and non-B HIV-1 primary isolates, using as gold standard the infectivity of each primary isolate in GHOST cells stably expressing HIV-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16dac2a63508b52ea8067142cde5e86e
https://pubmed.ncbi.nlm.nih.gov/22010208

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Identification of unusual and novel HIV type 1 spliced transcripts generated in vivo

Autor: Lucía Pérez-Álvarez, Milagros Pinilla, Cristina Carrera, Michael M. Thomson

Publikováno v: AIDS research and human retroviruses. 26(7)

HIV-1 transcripts are generated through a complex alternative splicing mechanism, resulting in the production of multiple RNAs coding for each viral protein. HIV-1 RNA splicing has been analyzed mostly in in vitro assays, and in vivo data are scarce.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::597271dd2a718a350bce87c2f01aa993
https://pubmed.ncbi.nlm.nih.gov/20624070

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Identification of a new HIV type 1 circulating BF intersubtype recombinant form (CRF47_BF) in Spain

Autor: Ana Maria Sánchez, Aurora Fernández-García, José Antonio Iribarren, Lucía Pérez-Álvarez, Valentina García, Matilde Trigo, Mercedes Muñoz-Nieto, Antonio Ocampo, Gustavo Cilla, Michael M. Thomson, Celia Miralles, Milagros Pinilla, Sonia Pérez-Castro, María Teresa Cuevas, M. González-Galeano, Rafael Ojea de Castro, Elena Delgado

Publikováno v: AIDS research and human retroviruses. 26(7)

We report the identification of a new HIV-1 circulating recombinant form (CRF47_BF) derived from subtypes B and F. It was initially identified in protease-reverse transcriptase sequences from nine individuals from three separate regions of Spain who

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0928bed3985695ea13a84e9df9fa5159
https://pubmed.ncbi.nlm.nih.gov/20618102

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Molecular epidemiology of HIV-1 in St Petersburg, Russia: predominance of subtype A, former Soviet Union variant, and identification of intrasubtype subclusters

Autor: Aleksey Yakovlev, María Teresa Cuevas, Aza Rakhmanova, Rafael Nájera, Milagros Pinilla, Yolanda Vega, Anna Vinogradova, Lucía Pérez-Álvarez, Mercedes Muñoz, Saladin Osmanov, Elena Delgado, Michael M. Thomson

Publikováno v: Journal of acquired immune deficiency syndromes (1999). 51(3)

Objectives: To examine HIV-1 genetic diversity in St. Petersburg. Methods: Partial HIV-1 pol sequences from 102 plasma samples collected in 2006 were analyzed with a Bayesian phylogeny inference method. Results: Subtype A, former Soviet Union (FSU) v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14edfe655f295791c930e75bebdef8d4
https://pubmed.ncbi.nlm.nih.gov/19363451

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