Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Milagros N Wong"'
Autor:
Patricia Bartsch, Christoph Kilian, Malte Hellmig, Hans-Joachim Paust, Alina Borchers, Amirrtavarshni Sivayoganathan, Leon Enk, Yu Zhao, Nikhat Shaikh, Henning Büttner, Milagros N Wong, Victor G Puelles, Thorsten Wiech, Richard Flavell, Tobias B Huber, Jan-Eric Turner, Stefan Bonn, Samuel Huber, Nicola Gagliani, Hans-Willi Mittrücker, Holger Rohde, Ulf Panzer, Christian F Krebs
Publikováno v:
PLoS Pathogens, Vol 18, Iss 4, p e1010430 (2022)
Staphylococcus aureus is frequently detected in patients with sepsis and thus represents a major health burden worldwide. CD4+ T helper cells are involved in the immune response to S. aureus by supporting antibody production and phagocytosis. In part
Externí odkaz:
https://doaj.org/article/380fd4269d2449729d87e44af873b2c2
Autor:
Fabian Braun, Ahmed Abed, Dominik Sellung, Manuel Rogg, Mathias Woidy, Oysten Eikrem, Nicola Wanner, Jessica Gambardella, Sandra D. Laufer, Fabian Haas, Milagros N. Wong, Bernhard Dumoulin, Paula Rischke, Anne Mühlig, Wiebke Sachs, Katharina von Cossel, Kristina Schulz, Nicole Muschol, Sören W. Gersting, Ania C. Muntau, Oliver Kretz, Oliver Hahn, Markus M. Rinschen, Michael Mauer, Tillmann Bork, Florian Grahammer, Wei Liang, Thorsten Eierhoff, Winfried Römer, Arne Hansen, Catherine Meyer-Schwesinger, Guido Iaccarino, Camilla Tøndel, Hans-Peter Marti, Behzad Najafian, Victor G. Puelles, Christoph Schell, Tobias B. Huber
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 11 (2023)
Current therapies for Fabry disease are based on reversing intracellular accumulation of globotriaosylceramide (Gb3) by enzyme replacement therapy (ERT) or chaperone-mediated stabilization of the defective enzyme, thereby alleviating lysosomal dysfun
Externí odkaz:
https://doaj.org/article/c82d0427278d4ae092a98644e9de535c
Autor:
Anna Woestemeier, Pasquale Scognamiglio, Yu Zhao, Jonas Wagner, Franziska Muscate, Christian Casar, Francesco Siracusa, Filippo Cortesi, Theodora Agalioti, Simone Müller, Adrian Sagebiel, Leonie Konczalla, Ramez Wahib, Karl-Frederick Karstens, Anastasios D. Giannou, Anna Duprée, Stefan Wolter, Milagros N. Wong, Anne K. Mühlig, Agata A. Bielecka, Vikas Bansal, Tianran Zhang, Oliver Mann, Victor G. Puelles, Tobias B. Huber, Ansgar W. Lohse, Jakob R. Izbicki, Noah W. Palm, Stefan Bonn, Samuel Huber, Nicola Gagliani
Publikováno v:
JCI Insight, Vol 8, Iss 1 (2023)
A role of CD4+ T cells during the progression from nonalcoholic fatty liver disease (NAFLD) to nonalcoholic steatohepatitis (NASH) has been suggested, but which polarization state of these cells characterizes this progression and the development of f
Externí odkaz:
https://doaj.org/article/bd1ff2fbaac043e9a2e870f55d257c09
Autor:
Marina Zimmermann, Martin Klaus, Milagros N. Wong, Ann-Katrin Thebille, Lukas Gernhold, Christoph Kuppe, Maurice Halder, Jennifer Kranz, Nicola Wanner, Fabian Braun, Sonia Wulf, Thorsten Wiech, Ulf Panzer, Christian F. Krebs, Elion Hoxha, Rafael Kramann, Tobias B. Huber, Stefan Bonn, Victor G. Puelles
Publikováno v:
JCI Insight, Vol 6, Iss 7 (2021)
Morphologic examination of tissue biopsies is essential for histopathological diagnosis. However, accurate and scalable cellular quantification in human samples remains challenging. Here, we present a deep learning–based approach for antigen-specif
Externí odkaz:
https://doaj.org/article/3c08e835153e4f5397578a86dbdc44f5
Autor:
Georg R. Herrnstadt, Christoph B. Niehus, Torben Ramcke, Julia Hagenstein, Laura-Isabell Ehnold, Anna Nosko, Matthias T. Warkotsch, Frederic C. Feindt, Simon Melderis, Hans-Joachim Paust, Varshi Sivayoganathan, Saskia-Larissa Jauch-Speer, Milagros N. Wong, Daniela Indenbirken, Christian F. Krebs, Tobias B. Huber, Ulf Panzer, Victor G. Puelles, Malte A. Kluger, Oliver M. Steinmetz
Publikováno v:
Kidney International.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a00e6e868d25cce4ec06aa3c4b43a15
https://doi.org/10.1016/j.kint.2023.02.027
https://doi.org/10.1016/j.kint.2023.02.027
Autor:
Nicola Wanner, Geoffroy Andrieux, Pau Badia-i-Mompel, Carolin Edler, Susanne Pfefferle, Maja T. Lindenmeyer, Christian Schmidt-Lauber, Jan Czogalla, Milagros N. Wong, Yusuke Okabayashi, Fabian Braun, Marc Lütgehetmann, Elisabeth Meister, Shun Lu, Maria L. M. Noriega, Thomas Günther, Adam Grundhoff, Nicole Fischer, Hanna Bräuninger, Diana Lindner, Dirk Westermann, Fabian Haas, Kevin Roedl, Stefan Kluge, Marylyn M. Addo, Samuel Huber, Ansgar W. Lohse, Jochen Reiser, Benjamin Ondruschka, Jan P. Sperhake, Julio Saez-Rodriguez, Melanie Boerries, Salim S. Hayek, Martin Aepfelbacher, Pietro Scaturro, Victor G. Puelles, Tobias B. Huber
Publikováno v:
Nature metabolism. 4(3)
Extrapulmonary manifestations of COVID-19 have gained attention due to their links to clinical outcomes and their potential long-term sequelae1. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) displays tropism towards several organs, inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::971f14428e63c45878eeb5702e71f1c3
https://pubmed.ncbi.nlm.nih.gov/35513009
https://pubmed.ncbi.nlm.nih.gov/35513009
Publikováno v:
Cell and Tissue Research
Crescentic glomerulonephritis represents a group of kidney diseases characterized by rapid loss of kidney function and the formation of glomerular crescents. While the role of the immune system has been extensively studied in relation to the developm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97d39db2e41f7b59000bf87d90036e3a
https://pubmed.ncbi.nlm.nih.gov/34453566
https://pubmed.ncbi.nlm.nih.gov/34453566
Autor:
Francesco Siracusa, Ansgar W. Lohse, Dominik Kylies, Filippo Cortesi, Yu Zhao, Mascha Binder, Nicola Gagliani, Susanne Pfefferle, Milagros N. Wong, Victor G. Puelles, Marissa Herrmann, Lidia Bosurgi, Christoph Schultheiß, Leon U. B. Enk, Patricia Bartsch, Stefan Bonn, Malte Hellmig, Ulf Panzer, Kevin Roedl, Dominik Jarczak, Elisa Rosati, Samuel Huber, Petra Bacher, Jan-Eric Turner, Christoph Kilian, Christian Krebs, Jan-Peter Sperhake, Ann-Christin Gnirck, Marc Lütgehetmann, Julian Schulze Zur-Wiesch, Stefan Steurer, Alina Borchers, Nicola Scheibel, Stefan Kluge, Marylyn M. Addo, Hans-Joachim Paust, Tobias B. Huber, Fabian Hausmann
Publikováno v:
Science Immunology. 6
Hyperinflammation contributes to lung injury and subsequent acute respiratory distress syndrome (ARDS) with high mortality in patients with severe coronavirus disease 2019 (COVID-19). To understand the underlying mechanisms involved in lung pathology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed4a5ccddc6a55c72f86683a58fce8cc
https://doi.org/10.1126/sciimmunol.abf6692
https://doi.org/10.1126/sciimmunol.abf6692
Autor:
Yu, Zhao, Christoph, Kilian, Jan-Eric, Turner, Lidia, Bosurgi, Kevin, Roedl, Patricia, Bartsch, Ann-Christin, Gnirck, Filippo, Cortesi, Christoph, Schultheiß, Malte, Hellmig, Leon U B, Enk, Fabian, Hausmann, Alina, Borchers, Milagros N, Wong, Hans-Joachim, Paust, Francesco, Siracusa, Nicola, Scheibel, Marissa, Herrmann, Elisa, Rosati, Petra, Bacher, Dominik, Kylies, Dominik, Jarczak, Marc, Lütgehetmann, Susanne, Pfefferle, Stefan, Steurer, Julian Schulze, Zur-Wiesch, Victor G, Puelles, Jan-Peter, Sperhake, Marylyn M, Addo, Ansgar W, Lohse, Mascha, Binder, Samuel, Huber, Tobias B, Huber, Stefan, Kluge, Stefan, Bonn, Ulf, Panzer, Nicola, Gagliani, Christian F, Krebs
Publikováno v:
Science Immunology
Tissue-resident memory-like TH17 cells are clonally expanded in bronchoalveolar lavage fluid of patients with severe COVID-19.
TH17 cells in severe COVID-19 Generation of T helper 17 (TH17) cells has been associated with immunopathogenesis in mu
TH17 cells in severe COVID-19 Generation of T helper 17 (TH17) cells has been associated with immunopathogenesis in mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2675600f39770b9bd5c6379d64da008e
https://pubmed.ncbi.nlm.nih.gov/33622974
https://pubmed.ncbi.nlm.nih.gov/33622974
Autor:
Tim Magnus, Nicole Fischer, Maura Dandri, Adam Grundhoff, Tobias B. Huber, Thomas Guenther, M. Luetgehetmann, Fabian Heinrich, Dominik Noerz, Manja Czech-Sioli, Lisa Oestereich, Markus Glatzel, Klaus Pueschel, Martin Aepfelbacher, C. Edler, Susanne Pfefferle, Milagros N. Wong, Susanne Krasemann, Alexander Carstens, Ann-Sophie Schroeder, Victor G. Puelles, Lena Allweiss
Stroke and central nervous system dysfunction are cardinal symptoms in critically ill corona virus disease 19 (COVID-19) patients. In an autopsy series of 32 COVID-19 patients, we investigated whether carotid arteries were infected with SARS-CoV-2 by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2eda3a0382943d159ed9a092b6f9cec2
https://doi.org/10.1101/2020.10.10.334458
https://doi.org/10.1101/2020.10.10.334458
