Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Milada Horynová"'
Publikováno v:
Cellular and Molecular Life Sciences. 70:829-839
Glycosylation abnormalities have been observed in autoimmune diseases and cancer. Here, we compare mechanisms of aberrant O-glycosylation, i.e., formation of Tn and sialyl-Tn structures, on MUC1 in breast cancer, and on IgA1 in an autoimmune disease,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25d3f7a98c7d1031ef0c821a3ad543b3
https://doi.org/10.1007/s00018-012-1082-6
https://doi.org/10.1007/s00018-012-1082-6
Publikováno v:
Protein Expression and Purification. 81:175-180
The human UDP-N-acetyl-α-D-galactosamine:polypeptide N-acetylgalactosaminyl-transferase 2 (GalNAc-T2) is one of the key enzymes that initiate synthesis of hinge-region O-linked glycans of human immunoglobulin A1 (IgA1). We designed secreted soluble
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55913ff345f1fde21d835d1471f1872b
https://doi.org/10.1016/j.pep.2011.10.006
https://doi.org/10.1016/j.pep.2011.10.006
Autor:
Milan Raska, Marek Šebela, Jiri Kunert, Evzen Weigl, René Lenobel, Alena Kasperova, Milada Horynová
Publikováno v:
Mycoses. 54:e456-e462
Cysteine dioxygenase (CDO, EC 1.13.11.20) catalyses the oxygenation of cysteine to cysteine sulphinic acid leading to the production of sulphite, sulphate and taurine as the final metabolites of cysteine catabolism. Keratinolytic fungi secrete sulphi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d88881553f092277e940141cf2f3a9b2
https://doi.org/10.1111/j.1439-0507.2010.01948.x
https://doi.org/10.1111/j.1439-0507.2010.01948.x
Autor:
Hitoshi Suzuki, Milada Horynová, Matthew B. Renfrow, Kazuo Takahashi, Tyler J. Stewart, Alena Vrablikova, Jan Novak, Lydie Czernekova, Milan Raska, Bruce A. Julian, Koshi Yamada
Publikováno v:
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 30(2)
Galactose-deficient O-glycans in the hinge region (HR) of immunoglobulin A1 (IgA1) play a key role in the pathogenesis of IgA nephropathy (IgAN). O-Glycans of circulatory IgA1 consist of N-acetylgalactosamine (GalNAc) with a β1,3-linked galactose; b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8afa5c9348a00ed897f05448d6fca9e3
https://pubmed.ncbi.nlm.nih.gov/25281698
https://pubmed.ncbi.nlm.nih.gov/25281698
Autor:
Milan Raska, Jan Novak, Zina Moldoveanu, Mogens Kilian, Stacy Hall, Bruce A. Julian, Knud Poulsen, Yukio Yuzawa, Matthew B. Renfrow, Milada Horynová, Kazuo Takahashi, Yoshiyuki Hiki
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 2, p e99026 (2014)
Takahashi, K, Raska, M, Stuchlova Horynova, M, Hall, S D, Poulsen, K, Kilian, M, Hiki, Y, Yuzawa, Y, Moldoveanu, Z, Julian, B A, Renfrow, M B & Novak, J 2014, ' Enzymatic sialylation of IgA1 o-glycans : implications for studies of IgA nephropathy ', PLOS ONE, vol. 9, no. 2, pp. e99026 . https://doi.org/10.1371/journal.pone.0099026
PLoS ONE, Vol 9, Iss 2, p e99026 (2014)
Takahashi, K, Raska, M, Stuchlova Horynova, M, Hall, S D, Poulsen, K, Kilian, M, Hiki, Y, Yuzawa, Y, Moldoveanu, Z, Julian, B A, Renfrow, M B & Novak, J 2014, ' Enzymatic sialylation of IgA1 o-glycans : implications for studies of IgA nephropathy ', PLOS ONE, vol. 9, no. 2, pp. e99026 . https://doi.org/10.1371/journal.pone.0099026
Patients with IgA nephropathy (IgAN) have elevated circulating levels of IgA1 with some O-glycans consisting of galactose (Gal)-deficient N-acetylgalactosamine (GalNAc) with or without N-acetylneuraminic acid (NeuAc). We have analyzed O-glycosylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32bf66f1812083710ed7287e03fd8aa1
https://pubmed.ncbi.nlm.nih.gov/24918438
https://pubmed.ncbi.nlm.nih.gov/24918438
Autor:
Eliška Bartheldyová, Milan Raska, Jana Plocková, Pavlína Turánek Knotigová, Marek Šebela, Josef Mašek, Miroslav Ledvina, Pavel Kulich, Ondřej Strouhal, Michal Křupka, Andrew D. Miller, Štěpán Koudelka, Jaroslav Turánek, Lýdie Czerneková, Kateřina Zachová, Milada Horynová, Zina Korvasová, Michaela Škrabalová
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 160(2)
Lyme disease caused by spirochete Borrelia burgdorferi sensu lato, is a tick-born illness. If the infection is not eliminated by the host immune system and/or antibiotics, it may further disseminate and cause severe chronic complications. The immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8a442e3f72688908090c4cd48b79bdf
https://pubmed.ncbi.nlm.nih.gov/22387453
https://pubmed.ncbi.nlm.nih.gov/22387453
Autor:
Štěpán Koudelka, Pavel Kulich, Jana Plocková, Milada Horynová, Milan Raska, Michal Křupka, Zina Korvasová, Pavlina Turanek-Knotigova, Irena Kratochvílová, Josef Mašek, Petra Škodová, Andrew D. Miller, Michaela Škrabalová, Miroslav Ledvina, Eliška Bartheldyová, Jaroslav Michálek, Jaroslav Turánek, Marek Šebela, Jana Vrbkova, Daniel Zýka, Lýdie Czerneková, Kateřina Zachová
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 151(2)
Hsp90-CA is present in cell wall of Candida pseudohyphae or hyphae-typical pathogenic morphotype for both systemic and mucosal Candida infections. Heat shock protein from Candida albicans (hsp90-CA) is an important target for protective antibodies du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6365b5416839018cf7e334e98f9bd3e
https://pubmed.ncbi.nlm.nih.gov/21256901
https://pubmed.ncbi.nlm.nih.gov/21256901
Autor:
Milada Horynová, Katerinat Zachova, Michal Krupka, Ivo Chamrad, Evzen Weigl, Milan Raska, Marek Šebela, Jana Belakova
Publikováno v:
Journal of Microbiology and Biotechnology.
Heat shock protein 70 kDa (hsp70), a molecular chaperone involved in folding of nascent proteins, has been studied for its ability to activate innate and specific immunity. High purity hsp70 preparation is generally required for immunization experime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8faa67e88b2146518b7008e1ffd5eca9
https://doi.org/10.4014/jmb.0810.570
https://doi.org/10.4014/jmb.0810.570
Publikováno v:
Scopus-Elsevier
Background: Borrelia burgdorferi sensu lato is a group of at least twelve closely related species some of which are responsible for Lyme disease, the most frequent zoonosis in Europe and the USA. Many of the biological features of Borrelia are unique
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2f3d85dfc2682f800450d4a7163703c
https://pubmed.ncbi.nlm.nih.gov/18345249
https://pubmed.ncbi.nlm.nih.gov/18345249
Publikováno v:
Archivum Immunologiae et Therapiae Experimentalis
Vaccination is historically one of the most successful strategies for the prevention of infectious diseases. For safety reasons, modern vaccinology tends toward the usage of inactivated or attenuated microorganisms and uses predominantly subunit vacc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::159b222ce5828cd40ddf1649dc2b55fb
http://europepmc.org/articles/PMC7079751
http://europepmc.org/articles/PMC7079751