Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Mila Lamb"'
Autor:
Erin C. Yang, Robby Divine, Marcos C. Miranda, Andrew J. Borst, Will Sheffler, Jason Z Zhang, Justin Decarreau, Amijai Saragovi, Mohamad Abedi, Nicolas Goldbach, Maggie Ahlrichs, Craig Dobbins, Alexis Hand, Suna Cheng, Mila Lamb, Paul M. Levine, Sidney Chan, Rebecca Skotheim, Jorge Fallas, George Ueda, Joshua Lubner, Masaharu Somiya, Alena Khmelinskaia, Neil P. King, David Baker
Publikováno v:
bioRxiv
Programming protein nanomaterials to respond to changes in environmental conditions is a current challenge for protein design and important for targeted delivery of biologics. We describe the design of octahedral non-porous nanoparticles with the thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08485ba26a36e4b67dd39fd83b59e0cd
https://doi.org/10.1101/2023.04.17.537263
https://doi.org/10.1101/2023.04.17.537263
Autor:
Paul M. Levine, Timothy W. Craven, Xinting Li, Aaron T. Balana, Gregory H. Bird, Marina Godes, Patrick J. Salveson, Patrick W. Erickson, Mila Lamb, Maggie Ahlrichs, Michael Murphy, Cassandra Ogohara, Meerit Y. Said, Loren D. Walensky, Matthew R. Pratt, David Baker
Publikováno v:
ACS Chem Biol
Peptide and protein bioconjugation technologies have revolutionized our ability to site-specifically or chemoselectively install a variety of functional groups for applications in chemical biology and medicine, including the enhancement of bioavailab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b694595cf409370fd01594d28a8eb682
https://pubmed.ncbi.nlm.nih.gov/35319882
https://pubmed.ncbi.nlm.nih.gov/35319882
Autor:
Florian Praetorius, Philip J. Y. Leung, Maxx H. Tessmer, Adam Broerman, Cullen Demakis, Acacia F. Dishman, Arvind Pillai, Abbas Idris, David Juergens, Justas Dauparas, Xinting Li, Paul M. Levine, Mila Lamb, Ryanne K. Ballard, Stacey R. Gerben, Hannah Nguyen, Alex Kang, Banumathi Sankaran, Asim K. Bera, Brian F. Volkman, Jeff Nivala, Stefan Stoll, David Baker
Proteins that switch between two structural states as a function of environmental stimuli are widespread in nature. These proteins structurally transduce biochemical information in a manner analogous to how transistors control information flow in com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ffd869139e74a9969afeb1fde7c1d01
https://doi.org/10.1101/2023.01.27.525968
https://doi.org/10.1101/2023.01.27.525968
Autor:
Danny D. Sahtoe, Ewa A. Andrzejewska, Hannah L. Han, Enrico Rennella, Matthias M. Schneider, Georg Meisl, Maggie Ahlrichs, Justin Decarreau, Hannah Nguyen, Alex Kang, Paul Levine, Mila Lamb, Xinting Li, Asim K. Bera, Lewis E. Kay, Tuomas P.J. Knowles, David Baker
Segments of proteins with β-strand propensity can self associate to form amyloid fibrils associated with many diseases. These regions often adopt alternative structures in their folded states, or are intrinsically disordered in solution, making it d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e438a9b349f9863535f67448f91f321
https://doi.org/10.1101/2023.01.13.523785
https://doi.org/10.1101/2023.01.13.523785
Autor:
Susana Vázquez Torres, Philip J. Y. Leung, Isaac D. Lutz, Preetham Venkatesh, Joseph L. Watson, Fabian Hink, Huu-Hien Huynh, Andy Hsien-Wei Yeh, David Juergens, Nathaniel R. Bennett, Andrew N. Hoofnagle, Eric Huang, Michael J MacCoss, Marc Expòsit, Gyu Rie Lee, Paul M. Levine, Xinting Li, Mila Lamb, Elif Nihal Korkmaz, Jeff Nivala, Lance Stewart, Joseph M. Rogers, David Baker
Many peptide hormones form an alpha-helix upon binding their receptors1–4, and sensitive detection methods for them could contribute to better clinical management.De novoprotein design can now generate binders with high affinity and specificity to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1f71e8af52449b591ee281d1a65d41b
https://doi.org/10.1101/2022.12.10.519862
https://doi.org/10.1101/2022.12.10.519862
Autor:
Neville P. Bethel, Andrew J. Borst, Fabio Parmeggiani, Matthew J. Bick, TJ Brunette, Hannah Nguyen, Alex Kang, Asim K. Bera, Lauren Carter, Marcos C. Miranda, Ryan Kibler, Mila Lamb, Xinting Li, Banumathi Sankaran, David Baker
Molecular systems with coincident cyclic and superhelical symmetry axes have considerable advantages for materials design as they can be readily lengthened or shortened by changing the length of the constituent monomers. Among proteins, alpha helical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::979e13b368bbe7502885eee453b2b36b
https://doi.org/10.1101/2022.10.14.511843
https://doi.org/10.1101/2022.10.14.511843